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IFN Omega Antibody (PA5-99819) in ICC/IF
Immunocytochemistry analysis of IFN Omega in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with IFN Omega polyclonal antibody (Product # PA5-99819) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated g... View More
Product Details
PA5-99819
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IFNW1(Accession P05000), corresponding to amino acid residues Y159-S195.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818752
Product Specific Information
Antibody detects endogenous levels of total IFNW1.
Target Information
IFN-omega is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds that are necessary for full biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IFN o; IFN ω; IFN-omega 1, interferon omega-1; IFNo; IFNomega; IFNW; IFNω; Interferon alpha-II-1; Interferon o; Interferon OMEGA; Interferon omega-1; Interferon ω; interferon, omega 1
Gene Aliases: IFNW1
UniProt ID: (Human) P05000
Entrez Gene ID: (Human) 3467
adaptive immune response
T cell activation involved in immune response
natural killer cell activation involved in immune response
humoral immune response
cell cycle arrest
response to virus
cytokine-mediated signaling pathway
B cell differentiation
positive regulation of peptidyl-serine phosphorylation of STAT protein
B cell proliferation
response to exogenous dsRNA
innate immune response
defense response to virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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