Product References
Suppressive effect of environmental tobacco smoke on murine Th2 cell-mediated nasal eosinophilic inflammation.
Asia Pacific allergy
Nishimura T,Kaminuma O,Saeki M,Kitamura N,Mori A,Hiroi T
MM701 was used in T-Cell Activation to investigate the effect of ETS on allergen-immunized and allergen-specific Th2 cell-transferred murine eosinophilic inflammation models and that of cigarette smoke extract (CSE) and nicotine on allergen-induced Th2 cell proliferation and interleukin (IL)-4 production.
Wed Apr 01 00:00:00 EDT 2020
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.
Cell reports
Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP
MM701 was used in an ELISA assay to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.
Tue Apr 14 00:00:00 EDT 2020
NKG2A is a NK cell exhaustion checkpoint for HCV persistence.
Nature communications
Zhang C,Wang XM,Li SR,Twelkmeyer T,Wang WH,Zhang SY,Wang SF,Chen JZ,Jin X,Wu YZ,Chen XW,Wang SD,Niu JQ,Chen HR,Tang H
MM701 was used In vivo to investigate how exhaustion is induced during chronic hepatitis C virus (HCV) infection.
Wed Apr 03 00:00:00 EDT 2019
Ag85-focused T-cell immune response controls Mycobacterium avium chronic infection.
PloS one
Cerqueira-Rodrigues B,Mendes A,Correia-Neves M,Nobrega C
MM701 was used in an ELISA assay to investigate if a T cell receptor repertoire mostly, but not exclusively, directed at Ag85 is sufficient to mount a protective immune response against Mycobacterium avium.
Mon Jun 25 00:00:00 EDT 2018
Spirulina lipopolysaccharides inhibit tumor growth in a Toll-like receptor 4-dependent manner by altering the cytokine milieu from interleukin-17/interleukin-23 to interferon-γ.
Oncology reports
Okuyama H,Tominaga A,Fukuoka S,Taguchi T,Kusumoto Y,Ono S
MM701 was used in blocking or activating experiment to compare the antitumor effects of Spirulina LPS to E. coli LPS in an MH134 hepatoma model
Wed Feb 01 00:00:00 EST 2017
Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.
Scientific reports
Ahmad F,Chung YW,Tang Y,Hockman SC,Liu S,Khan Y,Huo K,Billings E,Amar MJ,Remaley AT,Manganiello VC
MM701 was used in western blot to analyze regulation of NLRP3 inflammasome in adipose tissue by phosphodiesterase 3B (PDE3B)
Mon Jun 20 00:00:00 EDT 2016
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation.
Nature communications
Bulla R,Tripodo C,Rami D,Ling GS,Agostinis C,Guarnotta C,Zorzet S,Durigutto P,Botto M,Tedesco F
MM701 was used in flow cytometry to suggest that locally synthesized C1q promotes tumor growth
Mon Feb 01 00:00:00 EST 2016
Treadmill exercise induces murine cardiac allograft survival and generates regulatory T cell.
Transplant international : official journal of the European Society for Organ Transplantation
Uchiyama M,Jin X,Yin E,Shimokawa T,Niimi M
MM701 was used in ELISA to analyze induction of murine cardiac allograft survival and regulatory T cells from treadmill exercise
Sun Mar 01 00:00:00 EST 2015
Anti-interleukin-10R1 monoclonal antibody in combination with bacillus Calmette--Guérin is protective against bladder cancer metastasis in a murine orthotopic tumour model and demonstrates systemic specific anti-tumour immunity.
Clinical and experimental immunology
Newton MR,Askeland EJ,Andresen ED,Chehval VA,Wang X,Askeland RW,O'Donnell MA,Luo Y
MM701 was used in ELISA to study the ability of a combination of an anti-IL-10R1 monoclonal antibody and BCG to protect against lung metastasis in bladder cancer patients
Tue Jul 01 00:00:00 EDT 2014
Inchingorei-san (TJ-117) and Artemisiae Capillaris Herba Induced Prolonged Survival of Fully Mismatched Cardiac Allografts and Generated Regulatory Cells in Mice.
Evidence-based complementary and alternative medicine : eCAM
Jin X,Uchiyama M,Zhang Q,Hirai T,Niimi M
MM701 was used in ELISA to examine the effects of Inchingorei-san treatment on the alloimmune responses in a murine model of cardiac allograft transplantation
Thu Aug 23 00:00:00 EDT 2012
Auditory stimulation of opera music induced prolongation of murine cardiac allograft survival and maintained generation of regulatory CD4+CD25+ cells.
Journal of cardiothoracic surgery
Uchiyama M,Jin X,Zhang Q,Hirai T,Amano A,Bashuda H,Niimi M
MM701 was used in ELISA to assess the effect of sounds on alloimmune responses in a murine model of cardiac allograft transplantation
Fri Mar 23 00:00:00 EDT 2012
Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells.
Mucosal immunology
Liu W,Chen X,Evanoff DP,Luo Y
MM701 was used in ELISA to investigate the role of specific CD4+ T cells in bladder autoimmune inflammation
Fri Jul 01 00:00:00 EDT 2011
Triggering DTH and CTL activity by fd filamentous bacteriophages: role of CD4+ T cells in memory responses.
Journal of biomedicine & biotechnology
Del Pozzo G,Mascolo D,Sartorius R,Citro A,Barba P,D'Apice L,De Berardinis P
MM701 was used in ELISA to study the effect of fd filamentous bacteriophage infection on immune response
Tue Sep 14 00:00:00 EDT 2010
Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation.
Proceedings of the National Academy of Sciences of the United States of America
Hava DL,van der Wel N,Cohen N,Dascher CC,Houben D,León L,Agarwal S,Sugita M,van Zon M,Kent SC,Shams H,Peters PJ,Brenner MB
MM701 was used in ELISA to study the role of dendritic cells in antigen presentation
Tue Aug 12 00:00:00 EDT 2008
Immunotherapy of neuroblastoma by an Interleukin-21-secreting cell vaccine involves survivin as antigen.
Cancer immunology, immunotherapy : CII
Croce M,Meazza R,Orengo AM,Fabbi M,Borghi M,Ribatti D,Nico B,Carlini B,Pistoia V,Corrias MV,Ferrini S
MM701 was used in ELISA to study the therapeutic efficacy of IL-21-gene-modified cells in a syngeneic model of metastatic neuroblastoma
Sat Nov 01 00:00:00 EDT 2008
ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival.
Journal of immunology (Baltimore, Md. : 1950)
Akbari O,Stock P,Meyer EH,Freeman GJ,Sharpe AH,Umetsu DT,DeKruyff RH
MM701 was used in ELISA to study the role of ICOS/ICOSL interaction in CD4+ NKT cell function
Tue Apr 15 00:00:00 EDT 2008
Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy.
Journal of immunology (Baltimore, Md. : 1950)
Tian C,Ansari MJ,Paez-Cortez J,Bagley J,Godwin J,Donnarumma M,Sayegh MH,Iacomini J
MM701 was used in ELISA to determine whether the programmed death-1-programmed death ligand-1 pathway precipitates type 1 diabetes in young NOD mice
Thu Nov 15 00:00:00 EST 2007
Cytolysin-dependent escape of the bacterium from the phagosome is required but not sufficient for induction of the Th1 immune response against Listeria monocytogenes infection: distinct role of Listeriolysin O determined by cytolysin gene replacement.
Infection and immunity
Hara H,Kawamura I,Nomura T,Tominaga T,Tsuchiya K,Mitsuyama M
MM701 was used in ELISA to study the role of cytolysin-dependent escape of the bacterium from the phagosome in the induction of Th1 immune responses against Listeria monocytogenes infection
Wed Aug 01 00:00:00 EDT 2007
Oral attenuated Salmonella enterica serovar Typhimurium vaccine expressing codon-optimized HIV type 1 Gag enhanced intestinal immunity in mice.
AIDS research and human retroviruses
Tsunetsugu-Yokota Y,Ishige M,Murakami M
MM701 was used in ELISA to investigate the effect of oral attenuated Salmonella typhimurium vaccine
Thu Feb 01 00:00:00 EST 2007
IL-2 induces expression and secretion of IFN-gamma in murine peritoneal macrophages.
Journal of leukocyte biology
Puddu P,Carollo M,Pietraforte I,Spadaro F,Tombesi M,Ramoni C,Belardelli F,Gessani S
MM701 was used in ELISA to investigate the regulatory effect of interleukin 2 on the expression of interferon gamma in murine peritoneal macrophages
Thu Sep 01 00:00:00 EDT 2005
Independent protective effects for tumor necrosis factor and lymphotoxin alpha in the host response to Listeria monocytogenes infection.
Infection and immunity
Roach DR,Briscoe H,Saunders BM,Britton WJ
MM701 was used in ELISA to investigate the roles of tumor necrosis factor and lymphotoxin in host resistance to Listeria monocytogenes infection
Mon Aug 01 00:00:00 EDT 2005
Recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) expressing mouse IL-18 augments Th1 immunity and macrophage cytotoxicity.
Clinical and experimental immunology
Luo Y,Yamada H,Chen X,Ryan AA,Evanoff DP,Triccas JA,O'Donnell MA
MM701 was used in blocking/activating experiment to investigate the role of interleukin 18 during the regulation of immune response
Thu Jul 01 00:00:00 EDT 2004
T cell-derived tumour necrosis factor is essential, but not sufficient, for protection against Mycobacterium tuberculosis infection.
Clinical and experimental immunology
Saunders BM,Briscoe H,Britton WJ
MM701 was used in ELISA to investigate the effect of tumor necrosis factor for the prevention of M. tuberculosis infection
Sun Aug 01 00:00:00 EDT 2004
Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation
Aramaki O,Shirasugi N,Takayama T,Shimazu M,Kitajima M,Ikeda Y,Azuma M,Okumura K,Yagita H,Niimi M
MM701 was used in ELISA to determine the roles of PD-1 and its ligands in the induction of regulatory cells by intratracheal delivery of alloantigen
Thu Jan 15 00:00:00 EST 2004
Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells.
International immunology
Tokoyoda K,Tsujikawa K,Matsushita H,Ono Y,Hayashi T,Harada Y,Abe R,Kubo M,Yamamoto H
MM701 was used in ELISA to investigate the role of cAMP/PKA pathway for the modulation of interleukin 4 expression in T cells
Sat May 01 00:00:00 EDT 2004
Trypanosoma cruzi: the expansion of NK, T, and NKT cells in the experimental infection.
Experimental parasitology
Antúnez MI,Cardoni RL
MM701 was used in ELISA to investigate the expansion of natural killer, T, and natural killer T cells in the experimental infection
Wed Jul 07 00:00:00 EDT 2004
Induction of mucosal tolerance with recombinant Hev b 1 and recombinant Hev b 3 for prevention of latex allergy in BALB/c mice.
Clinical and experimental immunology
Hufnagl K,Wagner B,Winkler B,Baier K,Hochreiter R,Thalhamer J,Kraft D,Scheiner O,Breiteneder H,Wiedermann U
MM701 was used in ELISA to establish a mouse model of latex allergy using two major latex allergens Hev b 1 and Hev b 3 for sensitization
Fri Aug 01 00:00:00 EDT 2003
Human CD4+ T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950)
Hess SD,Egilmez NK,Bailey N,Anderson TM,Mathiowitz E,Bernstein SH,Bankert RB
MM701 was used in ELISA to study the interleukin 12 release mobilized CD4+ T cells present in human lung tumors and the role of interferon gamma in its anti-tumor efficacy
Wed Jan 01 00:00:00 EST 2003
The levels and patterns of cytokines produced by CD4 T lymphocytes of BALB/c mice infected with Leishmania major by inoculation into the ear dermis depend on the infectiousness and size of the inoculum.
Infection and immunity
Lang T,Courret N,Colle JH,Milon G,Antoine JC
MM701 was used in ELISA to investigate the cytokine profile after Leishmania major inoculation
Thu May 01 00:00:00 EDT 2003
Studies on the generation and maintenance of mucosal cytotoxic T lymphocytes against human immunodeficiency virus type 1 Gag in mice.
AIDS research and human retroviruses
Yoshizawa I,Mizuochi T,Ogata A,Murakami M,Yagita H,Takahashi Y,Mizuochi T,Takemori T,Tsunetsugu-Yokota Y
MM701 was used in ELISA to investigate the method of the mucosal immunity induction against HIV-1 in mice
Sun Jun 01 00:00:00 EDT 2003
Cancer immunotherapy with interleukin 12 and granulocyte-macrophage colony-stimulating factor-encapsulated microspheres: coinduction of innate and adaptive antitumor immunity and cure of disseminated disease.
Cancer research
Hill HC,Conway TF,Sabel MS,Jong YS,Mathiowitz E,Bankert RB,Egilmez NK
MM701 was used in ELISA to study the role of interleukin-12 and granulocyte macrophage colony-stimulating factor microspheres in both innate and adaptive antitumor immune responses
Sun Dec 15 00:00:00 EST 2002
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection.
Journal of immunology (Baltimore, Md. : 1950)
Roach DR,Bean AG,Demangel C,France MP,Briscoe H,Britton WJ
MM701 was used in ELISA to investigate the important roles of tumor necrosis factor in host resistance to mycobacterial infection
Wed May 01 00:00:00 EDT 2002
Dissociated linkage of cytokine-inducing activity and cytotoxicity to different domains of listeriolysin O from Listeria monocytogenes.
Infection and immunity
Kohda C,Kawamura I,Baba H,Nomura T,Ito Y,Kimoto T,Watanabe I,Mitsuyama M
MM701 was used in ELISA to study the linkage of cytokine-inducing activity and cytotoxicity to different domains of Listeria monocytogenes listeriolysin O
Fri Mar 01 00:00:00 EST 2002
The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo.
Journal of bacteriology
Smith RS,Harris SG,Phipps R,Iglewski B
MM701 was used in ELISA to investigate the effect of 3O-C12-HSL for inflammation induction in mice
Fri Feb 01 00:00:00 EST 2002
CD28-independent induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation
Chitnis T,Najafian N,Abdallah KA,Dong V,Yagita H,Sayegh MH,Khoury SJ
MM701 was used in ELISA to investigate the pathogenesis of experimental autoimmune encephalomyelitis
Thu Mar 01 00:00:00 EST 2001
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation
Chitnis T,Najafian N,Benou C,Salama AD,Grusby MJ,Sayegh MH,Khoury SJ
MM701 was used in ELISA to investigate the role of targeted disruption of STAT4 and STAT6
Sat Sep 01 00:00:00 EDT 2001
Immune response induced by airway sensitization after influenza A virus infection depends on timing of antigen exposure in mice.
Journal of virology
Yamamoto N,Suzuki S,Suzuki Y,Shirai A,Nakazawa M,Suzuki M,Takamasu T,Nagashima Y,Minami M,Ishigatsubo Y
MM701 was used in ELISA to characterize the airway immune response after influenza A virus infection
Mon Jan 01 00:00:00 EST 2001
Dietary ribonucleotides modulate type 1 and type 2 T-helper cell responses against ovalbumin in young BALB/cJ mice.
The Journal of nutrition
Jyonouchi H,Sun S,Winship T,Kuchan MJ
MM701 was used in ELISA to study the effect of dietary ribonucleotides obtained from yeast on the balance of Th1/Th2 responses against OVA in young BALB/cJ mice
Sun Apr 01 00:00:00 EST 2001
DNA encoding a single mycobacterial antigen protects against leprosy infection.
Vaccine
Martin E,Roche PW,Triccas JA,Britton WJ
MM701 was used in ELISA to investigate the effect of DNA encoding a single mycobacterial antigen for leprosy infection
Mon Jan 08 00:00:00 EST 2001
Partially TAP-independent protection against Listeria monocytogenes by H2-M3-restricted CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Rolph MS,Kaufmann SH
MM701 was used in ELISA to study the immune responses against Listeria monocytogenes
Sun Oct 15 00:00:00 EDT 2000
Protection against virulent Mycobacterium avium infection following DNA vaccination with the 35-kilodalton antigen is accompanied by induction of gamma interferon-secreting CD4(+) T cells.
Infection and immunity
Martin E,Kamath AT,Triccas JA,Britton WJ
MM701 was used in ELISA to investigate the effect of DNA vaccination with the 35-kDa antigen during M. avium infection.
Thu Jun 01 00:00:00 EDT 2000
Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity, but not protective efficacy against Mycobacterium tuberculosis.
Immunology
Kamath AT,Hanke T,Briscoe H,Britton WJ
MM701 was used in ELISA to investigate the effects of specific cytokines on immune response against Mycobacterium tuberculosis
Thu Apr 01 00:00:00 EST 1999
Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin.
Journal of immunology (Baltimore, Md. : 1950)
Bean AG,Roach DR,Briscoe H,France MP,Korner H,Sedgwick JD,Britton WJ
MM701 was used in ELISA to investigate the important roles of tumor necrosis factor in host susceptibility to Mycobacterium tuberculosis infection
Mon Mar 15 00:00:00 EST 1999
Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosis.
Infection and immunity
Kamath AT,Feng CG,Macdonald M,Briscoe H,Britton WJ
MM701 was used in ELISA to investigate the therapeutic potential of DNA vaccines against Mycobacterium tuberculosis infection
Thu Apr 01 00:00:00 EST 1999
Endogenous myelin basic protein inactivates the high avidity T cell repertoire.
The Journal of experimental medicine
Targoni OS,Lehmann PV
MM701 was used in ELISA to study the effect of myelin basic protein on high avidity T cells
Mon Jun 15 00:00:00 EDT 1998
Immunization of mice with phosphatidylcholine drastically reduces the parasitaemia of subsequent Plasmodium chabaudi chabaudi blood-stage infections.
Immunology
Bordmann G,Rudin W,Favre N
MM701 was used in ELISA to investigate the effect of phosphatidylcholine immunization on the parasitaemia of subsequent Plasmodium chabaudi infections
Fri May 01 00:00:00 EDT 1998
Generation, persistence, and modulation of Th0 effector cells: role of autocrine IL-4 and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950)
Miner KT,Croft M
MM701 was used in ELISA to investigate the roles of IL-4 and IFN-gamma on Th0 effector cells
Mon Jun 01 00:00:00 EDT 1998
Immune response against large tumors eradicated by treatment with cyclophosphamide and IL-12.
Journal of immunology (Baltimore, Md. : 1950)
Tsung K,Meko JB,Tsung YL,Peplinski GR,Norton JA
MM701 was used in immunohistochemistry to study the effect of cyclophosphamide and interleukin 12 on the immune responses against large tumors
Sun Feb 01 00:00:00 EST 1998
Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4.
Journal of immunology (Baltimore, Md. : 1950)
Assenmacher M,Löhning M,Scheffold A,Richter A,Miltenyi S,Schmitz J,Radbruch A
MM701 was used in ELISA to study the mechanism for T cell differentiation
Tue Sep 15 00:00:00 EDT 1998
CD40 ligation prevents neonatal induction of transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Flamand V,Donckier V,Demoor FX,Le Moine A,Matthys P,Vanderhaeghen ML,Tagawa Y,Iwakura Y,Billiau A,Abramowicz D,Goldman M
MM701 was used in blocking/activating experiment to study the effect of CD40 ligation on neonatal transplantation tolerance
Fri May 15 00:00:00 EDT 1998
CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.
The Journal of experimental medicine
Chu RS,Targoni OS,Krieg AM,Lehmann PV,Harding CV
MM701 was used in ELISA to study the effect of CpG oligodeoxynucleotides on T helper 1 immunity
Mon Nov 17 00:00:00 EST 1997
Humoral and cellular immunity in secondary infection due to murine Chlamydia trachomatis.
Infection and immunity
Williams DM,Grubbs BG,Pack E,Kelly K,Rank RG
MM701 was used in ELISA to study the role of murine Chlamydia trachomatis in secondary infection
Tue Jul 01 00:00:00 EDT 1997
Modulation of murine cytokine responses to mycobacterial antigens by helminth-induced T helper 2 cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Pearlman E,Kazura JW,Hazlett FE,Boom WH
MM701 was used in blocking/activating experiment to investigate the role of T helper 2 cell in murine cytokine immune responses
Mon Nov 01 00:00:00 EST 1993
Analysis of Th1 and Th2 cells in murine gut-associated tissues. Frequencies of CD4+ and CD8+ T cells that secrete IFN-gamma and IL-5.
Journal of immunology (Baltimore, Md. : 1950)
Taguchi T,McGhee JR,Coffman RL,Beagley KW,Eldridge JH,Takatsu K,Kiyono H
MM701 was used in ELISA to investigate the characteristics of Th1 and Th2 cells in mouse gut-associated tissues
Sun Jul 01 00:00:00 EDT 1990