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IFNGR1 Antibody (PA5-96413) in IHC (P)
Immunohistochemistry analysis of IFNGR1 in paraffin-embedded mouse spleen. Samples were incubated with IFNGR1 Polyclonal antibody (Product # PA5-96413) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
PA5-96413
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 270-489 of human IFNGR1 (NP_0004071)
Conjugate
Form
Liquid
Concentration
0.46 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808215
Product Specific Information
Immunogen sequence: IKKINPLKEK SIILPKSLIS VVRSATLETK PESKYVSLIT SYQPFSLEKE VVCEEPLSPA TVPGMHTEDN PGKVEHTEEL SSITEVVTTE ENIPDVVPGS HLTPIERESS SPLSSNQSEP GSIALNSYHS RNCSESDHSR NGFDTDSSCL ESHSSLSDSE FPPNNKGEIK TEGQELITVI KAPTSFGYDK PHVLVDLLVD DSGKESLIGY RPTEDSKEFS; Positive Samples: HL-60, THP-1, HeLa, SW620, Mouse lung, Mouse spleen, Mouse heart, Mouse skeletal muscle; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; immune interferon receptor 1; INF-g receptor; Interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain
Gene Aliases: CD119; Ifgr; IFN-gammaR; IFNGR; IFNGR1; IMD27A; IMD27B; Nktar
UniProt ID: (Human) P15260, (Mouse) P15261
Entrez Gene ID: (Human) 3459, (Mouse) 15979, (Rat) 116465
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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