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Invitrogen
IFNGR1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
IFNGR1 Antibody (PA5-99641) in WB
Western blot was performed using IFNGR1 Polyclonal Antibody (Product # PA5-99641) and band ranging between 60-70 kDa corresponding to IFNGR1 was observed in MCF 10A and in A549 cells upon treatment with IFN-gamma. Whole cell extracts (30 µg lysate) of A549 (Lane 1), A549 treated with IFN-gamma (1 µg/mL for 4 hours) (Lane 2), MCF7 (Lane 3) and MCF 10A (Lane 4) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX), 10 well. Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001... View More
Product Details
PA5-99641
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IFNGR1(Accession P15260), corresponding to amino acid residues P432-T482.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818574
Product Specific Information
Antibody detects endogenous levels of total IFNGR1.
Target Information
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; immune interferon receptor 1; INF-g receptor; Interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain
Gene Aliases: CD119; Ifgr; IFN-gammaR; IFNGR; IFNGR1; IMD27A; IMD27B; Nktar
UniProt ID: (Human) P15260, (Mouse) P15261
Entrez Gene ID: (Human) 3459, (Mouse) 15979
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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