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Immunogen sequence: TQKEDDCDE IQCQLAIPVS SLNSQYCVSA EGVLHVWGVT TEKSKEVCIT IFNSSIKGSL WIPVVAALLL FLVLSLVFIC FYIKKINPLK EKSIILPKSL ISVVRSATLE TKPESKYVSL ITSYQPFSLE KEVVCEEPLS PATVPGMHTE DNPGKVEHTE ELSSITEVVT TEENIPDVVP GSHLTPIERE SSSPLSSNQS EPGSIALNSY HSRNCSESDH SRNGFDTDSS CLESHSSLSD SEFPPNNKGE IKTEGQELIT VIKAPTSFGY DKPHVLVDLL VDDSGKESLI GYRPTEDSKE FS (189-489 aa encoded by BC005333)
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; immune interferon receptor 1; Interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor alpha chain
Gene Aliases: CD119; IFNGR; IFNGR1; IMD27A; IMD27B
UniProt ID: (Human) P15260
Entrez Gene ID: (Human) 3459
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