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IGFBP4 Antibody (MA5-43750) in IHC (P)
Immunohistochemistry of IGFBP4 in paraffin-embedded human liver tissue. Samples were incubated in monoclonal IGFBP4 antibody (Product # MA5-43750) using a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG at a dilution of 2 µg/mL and DAB.
Product Details
MA5-43750
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
A4
Immunogen
Asp22-Glu258 (Accession P22692), with N-terminal His Tag
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2912682
Target Information
This gene is a member of the insulin-like growth factor binding protein family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IBP-4; IGF-binding protein 4; IGFBP; IGFBP-4; Insulin like growth factor binding protein; insulin-like growth factor binding protein 4; Insulin-like growth factor-binding protein 4
Gene Aliases: BP-4; HT29-IGFBP; IBP4; IGF-BP4; IGFBP-4; IGFBP4
UniProt ID: (Human) P22692, (Rat) P21744
Entrez Gene ID: (Human) 3487, (Rat) 360622
skeletal system development
regulation of cell growth
DNA metabolic process
inflammatory response
signal transduction
cell proliferation
regulation of glucose metabolic process
positive regulation of MAPK cascade
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of insulin-like growth factor receptor signaling pathway
cellular protein metabolic process
type B pancreatic cell proliferation
negative regulation of canonical Wnt signaling pathway
intracellular signal transduction
regulation of growth
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