Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The antibody detects endogenous levels of total IGSF10 protein.
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calvaria mechanical force protein 608; CMF608; IgSF10; Immunoglobulin superfamily member 10; immunoglobulin superfamily, member 10
Gene Aliases: CMF608; IGSF10
UniProt ID: (Human) Q6WRI0
Entrez Gene ID: (Human) 285313
Molecular Function:
immunoglobulin superfamily cell adhesion molecule
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