Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse IGSF8.
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD316; CD81 partner 3; EWI-2; Glu-Trp-Ile EWI motif-containing protein 2; IgSF8; Immunoglobulin superfamily member 8; KCT-4; Keratinocyte-associated transmembrane protein 4; PG regulatory-like protein; PGRL; Prostaglandin regulatory-like protein
Gene Aliases: AA033172; AU041109; ESTM34; EWI-2; Ewi2; Igsf8; KCT-4; Kct4; PGRL; R75384
UniProt ID: (Mouse) Q8R366
Entrez Gene ID: (Mouse) 140559
Molecular Function:
immunoglobulin receptor superfamily
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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