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Product Details
H00064375-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IKZF4 (ENSP00000262032, 1 a.a. approximately 544 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDSRYLQLQL YLPSCSLLQG SGDSSLEKEF LGAPVGPSVS TPNSQHSSPS RSLSANSIKV EMYSDEESSR LLGPDERLLE KDDSVIVEDS LSEPLGYCDG SGPEPHSPGG IRLPNGKLKC DVCGMVCIGP NVLMVHKRSH TGERPFHCNQ CGASFTQKGN LLRHIKLHSG EKPFKCPFCN YACRRRDALT GHLRTHSVSS PTVGKPYKCN YCGRSYKQQS TLEEHKERCH NYLQSLSTEA QALAGQPGDE IRDLEMVPDS MLHSSSERPT FIDRLANSLT KRKRSTPQKF VGEKQMRFSL SDLPYDVNSG GYEKDVELVA HHSLEPGFGS SLAFVGAEHL RPLRLPPTNC ISELTPVISS VYTQMQPLPG RLELPGSREA GEGPEDLADG GPLLYRPRGP LTDPGASPSN GCQDSTDTES NHEDRVAGVV SLPQGPPPQP PPTIVVGRHS PAYAKEDPKP QEGLLRGTPG PSKEVLRVVG ESGEPVKAFK CEHCRILFLD HVMFTIHMGC HGFRDPFECN ICGYHSQDRY EFSSHIVRGE HKVG
Target Information
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IKAROS family zinc finger 4 (Eos); Ikaros family zinc finger protein 4; Zinc finger protein Eos; zinc finger protein, subfamily 1A, 4 (Eos); zinc finger transcription factor Eos
Gene Aliases: EOS; IKZF4; KIAA1782; ZNFN1A4
UniProt ID: (Human) Q9H2S9
Entrez Gene ID: (Human) 64375
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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