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Product Details
H00064375-M01A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
4E6
Immunogen
IKZF4 (NP_071910, 2 a.a. approximately 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: DSRYLQLQLY LPSCSLLQGS GDSSLEKEFL GAPVGPSVST PNSQHSSPSR SLSANSIKVE MYSDEESSRL LGPDERLLEK DDSVIVEDSL SEPLGYCDGS GPEPHSP
Target Information
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IKAROS family zinc finger 4 (Eos); Ikaros family zinc finger protein 4; Zinc finger protein Eos; zinc finger protein, subfamily 1A, 4 (Eos); zinc finger transcription factor Eos
Gene Aliases: EOS; IKZF4; KIAA1782; ZNFN1A4
UniProt ID: (Human) Q9H2S9
Entrez Gene ID: (Human) 64375
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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