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IL-11 Antibody (500-M11-500UG) in ELISA
Sandwich ELISA: Assuming 100 µL/well, a concentration of 2.0-4.0 µg/mL of IL-11 Monoclonal Antibody (Product # 500-M11-500UG) will detect Recombinant Human IL-11 when used with PeproTech IL-11 Polyclonal Antibody, Biotin (Product # 500-P01BT-1MG) as the detection antibody at a concentration of at least 1.0-2.0 µg/mL.
Product Details
500-M11-500UG
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
Class
Monoclonal
Type
Antibody
Immunogen
E.coli-derived Recombinant Human IL-11
Conjugate
Form
Lyophilized
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
RRID
AB_2942187
Product Specific Information
AA Sequence of recombinant protein: MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL.
Preparation: Produced in mice immunized with highly pure Recombinant Human IL-11. Anti-Human IL-11-specific antibody was purified from cell culture by Protein G affinity chromatography.
Target Information
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adipogenesis inhibitory factor; AGIF; il 11; IL-11; IL-11ra; IL10RA; IL11 inhibitor; ILN; Interleukin; Interleukin-11; Interleukin11; MGC2146; oprelvekin
Gene Aliases: AGIF; IL-11; IL11
UniProt ID: (Human) P20809
Entrez Gene ID: (Human) 3589
cell-cell signaling
positive regulation of cell proliferation
B cell differentiation
megakaryocyte differentiation
positive regulation of peptidyl-serine phosphorylation
positive regulation of MAPK cascade
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of hormone secretion
positive regulation of peptidyl-tyrosine phosphorylation
regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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