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IL-11 Antibody (PA5-47594) in Neu
Neutralization of IL-11 in T11 mouse plasmacytoma cell line. Samples were incubated in IL-11 polyclonal antibody (Product # PA5-47594). Recombinant Mouse IL‚11 stimulates proliferation in the T11 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse IL‚11 (0.75 ng/mL) is neutralized (green line) by increasing concentrations of Mouse IL‚11 Antigen Affinity-purified Polyclonal Antibody. The ND50 is typically 8-50 ng/mL.
Product Details
PA5-47594
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant mouse IL-11 Gly23-Leu199
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608724
Product Specific Information
In direct ELISAs, approximately 50% cross-reactivity with recombinant human IL-11 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: il 11; IL-11; IL-11ra; IL10RA; IL11 inhibitor; ILN; Interleukin; Interleukin-11; Interleukin11; MGC2146
Gene Aliases: IL-11; Il11
UniProt ID: (Mouse) P47873
Entrez Gene ID: (Mouse) 16156
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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