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IL-16 Antibody (PA5-145465) in WB
Western blot analysis of IL-16 in various lysates. Samples were incubated with IL-16 polyclonal antibody (Product # PA5-145465) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG secondary antibody at a dilution of 0.2 µg/mL. Lane 1: Gallus Cerebrum lysate; Lane 2: Jurkat cell lysate.
Product Details
PA5-145465
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Chicken IL16 protein, Ser1183-Leu1454 (Accession #Q70XC4)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3091385
Target Information
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine; FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; ILN; Interleukin; interleukin 16 (lymphocyte chemoattractant factor); Interleukin16; lymphocyte chemoattractant factor; M-IL-16; neuronal interleukin 16; Pro-interleukin-16; prointerleukin 16
Gene Aliases: IL16; interleukin-16; LCF; NIL16; prIL-16; PRIL16
UniProt ID: (Human) Q14005
Entrez Gene ID: (Human) 3603, (Chicken) 374270
Performance Guarantee
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