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IL-16 Antibody (PA5-78023) in IHC (P)
IL-16 Polyclonal Antibody detects IL16 protein at secreted on human normal colon by immunohistochemical analysis. Sample: Paraffin-embedded human normal colon. IL-16 Polyclonal Antibody (Product # PA5-78023) diluted at 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-78023
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IL16. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.73 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 0.1M glycine, 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2735954
Product Specific Information
Positive Control: A549, Jurkat, NT2D1
Predicted Reactivity: Chimpanzee (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; ILN; Interleukin; Interleukin16; lymphocyte chemoattractant factor; M-IL-16; neuronal interleukin 16; Pro-interleukin-16; prointerleukin 16
Gene Aliases: IL16; LCF; NIL16; prIL-16; PRIL16
UniProt ID: (Human) Q14005
Entrez Gene ID: (Human) 3603
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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