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Product Details
66145-1-IG
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1C4C7
Immunogen
IL-16 Fusion Protein Ag16466 (154-454 aa encoded by BC040272)
Conjugate
Form
Liquid
Concentration
1.52 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTKKSAAPT DRQPYSLCSN RKSLSQQLDC PAGKAAGTSR PTRSLSTAQL VQPSGGLQAS VISNIVLMKG QAKGLGFSIV GGKDSIYGPI GIYVKTIFAG GAAAADGRLQ EGDEILELNG ESMAGLTHQD ALQKFKQAKK GLLTLTVRTR LTAPPSLCSH LSPPLCRSLS SSTCITKDSS SFALESPSAP ISTAKPNYRI MVEVSLQKEA GVGLGIGLCS VPYFQCISGI FVHTLSPGSV AHLDGRLRCG DEIVEISDSP VHCLTLNEVY TILSHCDPGP VSIIVSRHPD PQKEEMEAQE VK (154-454 aa encoded by BC040272)
Target Information
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; ILN; Interleukin; Interleukin16; lymphocyte chemoattractant factor; M-IL-16; neuronal interleukin 16; Pro-interleukin-16; prointerleukin 16
Gene Aliases: IL16; LCF; NIL16; prIL-16; PRIL16
UniProt ID: (Human) Q14005
Entrez Gene ID: (Human) 3603
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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