Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cytokine receptor CRL4; Cytokine receptor-like 4; ecotropic viral integration site 27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17ER; IL-17RB; IL-17Rh1; interleukin 17 receptor homolog 1; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; ZCYTO7
Gene Aliases: CRL4; EVI27; IL-17ER; IL-17Rh1; IL17BR; IL17RB; IL17RH1; UNQ2501/PRO19612
UniProt ID: (Human) Q9NRM6, (Mouse) Q9JIP3
Entrez Gene ID: (Human) 55540, (Mouse) 50905, (Rat) 306247
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support