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IL-19 Antibody (MA5-41618) in IHC (P)
Immunohistochemistry analysis of IL-19 in paraffin-embedded Human Cerebrum tissue. Samples were incubated with monoclonal antibody (Product # MA5-41618) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 2 µg/mL.
Product Details
MA5-41618
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
C9
Immunogen
Recombinant protein Interleukin 19. The antigen corresponds to amino acid range 25-177 of the target protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899100
Target Information
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: il 19; IL-19; ILN; Interleukin; Interleukin-19; Interleukin19; MDA-1; melanoma differentiation associated protein-like protein; Melanoma differentiation-associated protein-like protein; NG.1
Gene Aliases: IL-10C; IL19; MDA1; NG.1; ZMDA1
UniProt ID: (Human) Q9UHD0
Entrez Gene ID: (Human) 29949
apoptotic process
inflammatory response
immune response
signal transduction
interleukin-6 biosynthetic process
positive regulation of JAK-STAT cascade
reactive oxygen species metabolic process
negative regulation of extrinsic apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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