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Invitrogen
IL-20 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
IL-20 Antibody (PA5-47067) in Neu
Neutralization of IL-20 in BaF3 mouse pro-B cell line co-transfected with human IL-20 Rα and IL-20 Rβ. Samples were incubated in IL-20 polyclonal antibody (Product # PA5-47067). Recombinant Human IL-20 stimulates proliferation in the BaF3 mouse pro-B cell line co-transfected with human IL-20 Rα and IL-20 Rβ in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-20 (2 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human IL-20 Antigen Affinity-purified Polyclonal Antibody. The N... View More
Product Details
PA5-47067
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human IL-20 Leu25-Glu176
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2576908
Product Specific Information
In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) IL-19 is observed, approximately 15% cross-reactivity with recombinant mouse IL-20 is observed, and less than 1% cross-reactivity with rhIL-10 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Cytokines that signal through Class II receptors form a distinct family that includes the interferons and interleukin 10 (IL-10). Recent identification of several IL-10 homologs has defined a cytokine subfamily that includes AK155, IL-19, IL-20, IL-22, and IL-24. IL-20 belongs to the IL-10 family and plays a role in skin inflammation and the development of hematopoietic cells. Little is known about its other biological functions and clinical implications. These cytokines display pro-inflammatory activities in different tissues, including skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytokine Zcyto10; four alpha helix cytokine; il 20; IL-20; ILN; Interleukin; Interleukin-20; MGC96907; PRO1801; UNQ852
Gene Aliases: IL-20; IL10D; IL20; UNQ852/PRO1801; ZCYTO10
UniProt ID: (Human) Q9NYY1
Entrez Gene ID: (Human) 50604
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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