Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
IL-20 Antibody (PA5-47092) in Neu
Neutralization of IL-20 in BaF3 mouse pro-B cell line co-transfected with human IL-20 Rα and IL-20 Rβ. Samples were incubated in IL-20 polyclonal antibody (Product # PA5-47092). Recombinant Mouse IL-20 stimulates proliferation in the BaF3 mouse pro-B cell line co-transfected with human IL-20 Rα and IL-20 Rβ in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse IL-20 (10 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IL-20 Antigen Affinity-purified Polyclonal Antibody. The ... View More
Product Details
PA5-47092
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant mouse IL-20 Leu25-Leu176
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2577139
Product Specific Information
In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human IL-20 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Cytokines that signal through Class II receptors form a distinct family that includes the interferons and interleukin 10 (IL-10). Recent identification of several IL-10 homologs has defined a cytokine subfamily that includes AK155, IL-19, IL-20, IL-22, and IL-24. IL-20 belongs to the IL-10 family and plays a role in skin inflammation and the development of hematopoietic cells. Little is known about its other biological functions and clinical implications. These cytokines display pro-inflammatory activities in different tissues, including skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cytokine Zcyto10; four alpha helix cytokine ZCYTO10; four helix bundle cytokine 10; il 20; IL-20; ILN; Interleukin; Interleukin-20; MGC96907; PRO1801; UNQ852
Gene Aliases: Il20; Zcyto10
UniProt ID: (Mouse) Q9JKV9
Entrez Gene ID: (Mouse) 58181
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support