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IL-25 Antibody (MA5-23568) in Flow
Flow cytometry of IL-25 in PC‚3 human prostate cancer cell line. Samples were incubated in IL-25 monoclonal antibody (Product # MA5-23568) or isotype control. To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer and permeabilized with Flow Cytometry Permeabilization/Wash Buffer.
Product Details
MA5-23568
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
182203
Immunogen
E. coli-derived recombinant human IL-17E Tyr33-Gly177
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
Buffered saline solution with BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2605470
Product Specific Information
This antibody shows 100% cross-reactivity with recombinant mouse IL-17E and no cross-reactivity with recombinant human (rh) IL-17, rhIL-17B, rhIL-17C, or rhIL-17F.
Target Information
Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: il 17e; IL-17E; IL-25; ILN; Interleukin; Interleukin-17E; Interleukin-25
Gene Aliases: IL17E; IL25; UNQ3120/PRO10272
UniProt ID: (Human) Q9H293
Entrez Gene ID: (Human) 64806
inflammatory response to antigenic stimulus
inflammatory response
cell surface receptor signaling pathway
biological_process
response to fungus
response to nematode
eosinophil differentiation
interleukin-13 production
interleukin-5 production
positive regulation of transcription from RNA polymerase II promoter
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