Product References
Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity.
Nature immunology
Hu W,Wang ZM,Feng Y,Schizas M,Hoyos BE,van der Veeken J,Verter JG,Bou-Puerto R,Rudensky AY
25-7042-82 was used in flow cytometry to show that Treg cells are functional in settings of established broad-spectrum systemic inflammation and are capable of affording sustained reset of immune homeostasis.
Wed Sep 01 00:00:00 EDT 2021
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
PLoS pathogens
Kastelberg B,Tubau-Juni N,Ayubi T,Leung A,Leber A,Hontecillas R,Bassaganya-Riera J,Kale SD
Published figure using IL-4 monoclonal antibody (Product # 25-7042-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
25-7042 was used in Flow cytometry/Cell sorting to study DEK-targeting aptamer in EMT-mediated airway remodeling in asthma.
Tue Dec 01 00:00:00 EST 2020
Plasma Transfusion Promoted Reprogramming CD4+ T Lymphocytes Immune Response in Severe Sepsis Mice Model Through Modulating the Exosome Protein Galectin 9.
Cell transplantation
Zhang L,Zhang JP,Liu Y,Wang H,Cheng Y,Wang JH,Zhang WJ,Li ZZ,Guo JR
25-7042 was used in Flow cytometry/Cell sorting to investigate the roles of fresh frozen plasma transfusion in severe sepsis mice model.
Mon Jul 19 00:00:00 EDT 2021
A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy.
Oncoimmunology
Casadesús AV,Deligne C,Diallo BK,Sosa K,Josseaume N,Mesa C,León K,Hernández T,Teillaud JL
25-7042 was used in Flow cytometry/Cell sorting to show that the combination of anti-tumor antibodies and no-alpha mutein is a promising approach to improve the therapeutic effect of these antibodies by potentiating NK/macrophage-mediated innate immunity and the adaptive T-cell response.
Tue Jun 02 00:00:00 EDT 2020
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
25-7042 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using IL-4 monoclonal antibody (Product # 25-7042-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner.
PloS one
Watanabe N,Kaminuma O,Kitamura N,Hiroi T
25-7042 was used in Flow cytometry/Cell sorting to study whether Th17 and Tregs that promote and suppress inflammatory responses, respectively, work with or against each other in immune reactions, showing that cotransfer of Th17 and induced Tregs led to increased inflammation, and blockage of CTLA4 led to abrogation of this effect.
Mon Aug 01 00:00:00 EDT 2016
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Nature immunology
Pierson W,Cauwe B,Policheni A,Schlenner SM,Franckaert D,Berges J,Humblet-Baron S,Schönefeldt S,Herold MJ,Hildeman D,Strasser A,Bouillet P,Lu LF,Matthys P,Freitas AA,Luther RJ,Weaver CT,Dooley J,Gray DH,Liston A
25-7042 was used in Flow cytometry/Cell sorting to study the regulation of the Foxp3+ T cell pool by proliferation and apoptosis, and specifically the role of antiapoptoic Mcl-1 in T cell survival.
Sun Sep 01 00:00:00 EDT 2013
Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.
Journal of autoimmunity
Tian L,De Hertogh G,Fedeli M,Staats KA,Schonefeldt S,Humblet-Baron S,Van Den Bosch L,Dellabona P,Dooley J,Liston A
25-7042 was used in Flow cytometry/Cell sorting to elucidate the dominant effects of the T cell microRNA expression network and explore it as a potential therapeutic target for autoimmune diseases.
Wed Feb 01 00:00:00 EST 2012
IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Altin JA,Goodnow CC,Cook MC
25-7042 was used in Flow cytometry/Cell sorting to investigate the mechanism and molecules involved in the formation of IL10+CTLA-4+Th2 inhibitory cells during chronic inflammation.
Fri Jun 01 00:00:00 EDT 2012
Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis.
Journal of immunology (Baltimore, Md. : 1950)
Obata Y,Takahashi D,Ebisawa M,Kakiguchi K,Yonemura S,Jinnohara T,Kanaya T,Fujimura Y,Ohmae M,Hase K,Ohno H
25-7042 was used in Flow cytometry/Cell sorting to demonstrate that mice with an IEC-specific deletion in a TF that mediates Notch signalling spontaneously develop colitis.
Thu Mar 01 00:00:00 EST 2012
The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
PloS one
Qi Y,Operario DJ,Georas SN,Mosmann TR
25-7042 was used in in vitro experiments to collate a detailed analysis of the regulation of Amphiregulin expression by human T cell subsets.
Thu Dec 13 00:00:00 EST 2012
The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
PloS one
Qi Y,Operario DJ,Georas SN,Mosmann TR
25-7042 was used in in vitro experiments to collate a detailed analysis of the regulation of Amphiregulin expression by human T cell subsets.
Thu Dec 13 00:00:00 EST 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
25-7042 was used in Flow cytometry/Cell sorting to demonstrate that soluble divalent MHC class II molecules can abrogate pathogenic T cells in experimental autoimmune encephalomyelitis.
Fri Jul 19 00:00:00 EDT 2013
IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression.
Blood
Milpied P,Massot B,Renand A,Diem S,Herbelin A,Leite-de-Moraes M,Rubio MT,Hermine O
25-7042 was used in Flow cytometry/Cell sorting to determine the function of recent thymic emigrant invariant natural killer (RTE TiNKT) cells in naive mice.
Thu Sep 15 00:00:00 EDT 2011
Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis.
Blood
Tian L,Altin JA,Makaroff LE,Franckaert D,Cook MC,Goodnow CC,Dooley J,Liston A
25-7042 was used in Immunocytochemistry to demonstrate that Th2-driven diseases may be more responsive to regulatory T-cell manipulation.
Thu Aug 18 00:00:00 EDT 2011
Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.
Journal of immunology (Baltimore, Md. : 1950)
Astrakhan A,Ochs HD,Rawlings DJ
25-7042 was used in Flow cytometry/Cell sorting to investigate the role for WASp within the iNKT lineage.
Mon Jun 15 00:00:00 EDT 2009
Methods for detection, isolation and culture of mouse and human invariant NKT cells.
Nature protocols
Watarai H,Nakagawa R,Omori-Miyake M,Dashtsoodol N,Taniguchi M
25-7042-82 was used in Flow cytometry/Cell sorting to describe a protocol to identify, purify and culture CD1d restricted invariant natural killer T (iNKT) cells from mouse tissue or human blood samples.
Tue Feb 19 00:00:00 EST 2008