Product References
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Neural regeneration research
Yu Y,Xia LK,Di Y,Nie QZ,Chen XL
Mon May 01 00:00:00 EDT 2023
Novel insights into the effect of deer IGF-1 on chondrocyte viability and IL-1β-induced inflammation response.
Journal of biochemical and molecular toxicology
Zhong J,Zhang J,Zhou Z,Pan D,Zhao D,Dong H,Yao B
Sun Jan 01 00:00:00 EST 2023
Inflammatory mechanisms of Ginkgo Biloba extract in improving memory functions through lncRNA-COX2/NF-κB pathway in mice with status epilepticus.
CNS neuroscience & therapeutics
Zou X,Liu S,Zou H,Zhou W,Fu H,Wei J,Zhang J,Zeng H,Tan T,Zhou W,Wu H,Chen X,Zhou X
Sun Jan 01 00:00:00 EST 2023
Overexpression of MicroRNA-155 aggravates pulpitis by targeting kinesin superfamily Proteins-5C based on illumina high-throughput sequencing.
International endodontic journal
Jiang Y,He Y,Chen Y,Zeng J,Huang W,Huang L,Luo J,Ma Y,Wu L,Yang X
Sat Jul 01 00:00:00 EDT 2023
The Correlation between Increased Expressions of NLRP3 Inflammasome Components in Peripheral Blood Mono-Nuclear Cells and Plaque Vulnerability in Human Carotid Atherosclerosis.
Iranian journal of public health
Xie W,Shi X,Lee H,Wang L,Niu N,Qu P
Sun Jan 01 00:00:00 EST 2023
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
International immunopharmacology
Wang P,Li T,Niu C,Sun S,Liu D
Wed Mar 01 00:00:00 EST 2023
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
Biochemical and biophysical research communications
Zeng S,Tao M,Yuan L,Zhang L,Luo X
Sun Apr 23 00:00:00 EDT 2023
Electroacupuncture ameliorates surgery-induced spatial memory deficits by promoting mitophagy in rats.
Annals of translational medicine
Guo J,Niu K,Ma BF,Sun LN,Fang QW,An JX
Tue Jan 31 00:00:00 EST 2023
Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine model of OVA-induced asthma.
Journal of ethnopharmacology
Jie XL,Luo ZR,Yu J,Tong ZR,Li QQ,Wu JH,Tao Y,Feng PS,Lan JP,Wang P
Tue Dec 05 00:00:00 EST 2023
Forsythiaside A Alleviates Lipopolysaccharide-Induced Acute Liver Injury through Inhibiting Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation.
Biological & pharmaceutical bulletin
Fu JN,Liu SC,Chen Y,Zhao J,Lu N,Ma T
Sat Jul 01 00:00:00 EDT 2023
Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway.
Frontiers in pharmacology
Sun X,Chen Z,Yu L,Zeng W,Sun B,Fan H,Bai Y
Sun Jun 11 00:00:00 EDT 2023
Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression.
Journal of nanobiotechnology
Wang Y,Zheng G,Xie X,Yu W,Wang J,Zang F,Yang C,Xiao Q,Zhang R,Wei L,Wu X,Liang L,Cao P,Xu C,Li J,Hu B,Zhang T,Wu J,Chen H
Fri Mar 03 00:00:00 EST 2023
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Phytotherapy research : PTR
Wang L,Wang X,Kong L,Li Y,Huang K,Wu J,Wang C,Sun H,Sun P,Gu J,Luo H,Liu K,Meng Q
Tue Feb 01 00:00:00 EST 2022
NLRP3 neuroinflammatory factors may be involved in atopic dermatitis mental disorders: an animal study.
Frontiers in pharmacology
Yuan H,Sun Y,Zhang S,Feng J,Tian Z,Liu J,Wang H,Gao Y,Tang Y,Zheng F
Sat Oct 22 00:00:00 EDT 2022
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Arthritis research & therapy
Yu H,Li M,Wen X,Yang J,Liang X,Li X,Bao X,Shu J,Ren X,Chen W,Li Z,Li Y
Fri Apr 29 00:00:00 EDT 2022
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
International journal of biological macromolecules
Wang Y,Wang Q,Duan L,Li X,Yang W,Huang T,Kong M,Guan F,Ma S
Thu Dec 01 00:00:00 EST 2022
Vascular endothelial growth factor attenuates neointimal hyperplasia of decellularized small-diameter vascular grafts by modulating the local inflammatory response.
Frontiers in bioengineering and biotechnology
Xie X,Wu Q,Liu Y,Chen C,Chen Z,Xie C,Song M,Jiang Z,Qi X,Liu S,Tang Z,Wu Z
Wed Jan 11 00:00:00 EST 2023
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Molecular brain
Xu B,Yang R,Yang B,Li L,Chen J,Fu J,Qu X,Huo D,Tan C,Chen H,Peng Z,Wang X
Mon Jan 03 00:00:00 EST 2022
Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway.
Drug design, development and therapy
Liu ZN,Su QQ,Wang YH,Wu X,Lv XW
Fri Apr 22 00:00:00 EDT 2022
In vitro and in vivo effects of hyperglycemia and diabetes mellitus on nucleus pulposus cell senescence.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Jiang Z,Jiang C,Jin L,Chen Z,Feng Z,Jiang X,Cao Y
Sat Oct 01 00:00:00 EDT 2022
Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways.
European journal of pharmacology
Zhang L,Zhu XZ,Badamjav R,Zhang JZ,Kou JP,Yu BY,Li F
Tue Feb 15 00:00:00 EST 2022
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
International journal of molecular sciences
Zhou P,Lai J,Li Y,Deng J,Zhao C,Huang Q,Yang F,Yang S,Wu Y,Tang X,Huang F,Wang L,Huang X,Zou W,Wu J
Mon Nov 14 00:00:00 EST 2022
β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows.
Frontiers in veterinary science
Dong Z,Sun X,Tang Y,Luo S,Jia H,Xu Q,Jiang Q,Loor JJ,Xu W,Xu C
Sat Sep 17 00:00:00 EDT 2022
A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease.
Thyroid : official journal of the American Thyroid Association
Hai YP,Saeed MEM,Ponto KA,Elflein HM,Lee ACH,Fang S,Zhou H,Frommer L,Längericht J,Efferth T,Kahaly GJ
Thu Dec 01 00:00:00 EST 2022
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Frontiers in bioengineering and biotechnology
Ding Q,Liu W,Liu X,Ding C,Zhao Y,Dong L,Chen H,Sun S,Zhang Y,Zhang J,Wu M
Sat Jul 16 00:00:00 EDT 2022
TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis.
BioMed research international
Liu S,Wu J,Chen P,Mohammed SAD,Zhang J,Liu S
Mon Aug 29 00:00:00 EDT 2022
Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity.
Journal of ethnopharmacology
Lin L,Chen Y,Li Q,Xu G,Ding K,Ren L,Shi W,Wang Y,Li Z,Dai W,Wei Z,Yang Y,Bai Z,Xiao X
Tue Mar 01 00:00:00 EST 2022
l-Arginine prevents 4-hydroxy-2-nonenal accumulation and depresses inflammation via inhibiting NF-κB activation.
Journal of biochemical and molecular toxicology
Liang M,Wang Z,Li H,Liu B,Yang L
Mon Aug 01 00:00:00 EDT 2022
P2Y14 receptor in trigeminal ganglion contributes to neuropathic pain in mice.
European journal of pharmacology
Lin J,Fang X,Liu F,Zhang Y,Li Y,Fang Z,Tang Q,Li C,Zhou C,Shen J
Thu Sep 15 00:00:00 EDT 2022
Metformin Improves the Prognosis of Adult Mice with Sepsis-Associated Encephalopathy Better than That of Aged Mice.
Journal of immunology research
Song G,Liang H,Song H,Ding X,Wang D,Zhang X,Sun T
Thu May 19 00:00:00 EDT 2022
Empagliflozin inhibits macrophage inflammation through AMPK signaling pathway and plays an anti-atherosclerosis role.
International journal of cardiology
Fu J,Xu H,Wu F,Tu Q,Dong X,Xie H,Cao Z
Tue Nov 15 00:00:00 EST 2022
Hexyl-aminolevulinate ethosome-mediated photodynamic therapy against acne: in vitro and in vivo analyses.
Drug delivery and translational research
Wang T,Wu L,Wang Y,Song J,Zhang F,Zhu X
Sat Jan 01 00:00:00 EST 2022
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
International journal of molecular medicine
Wang Y,Xie W,Feng Y,Xu Z,He Y,Xiong Y,Chen L,Li X,Liu J,Liu G,Wu Q
Fri Jul 01 00:00:00 EDT 2022
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Food & function
Bai X,Fu R,Duan Z,Liu Y,Zhu C,Fan D
Wed Apr 07 00:00:00 EDT 2021
The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3.
Frontiers in immunology
Tang T,Li P,Zhou X,Wang R,Fan X,Yang M,Qi K
Wed Jan 05 00:00:00 EST 2022
The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3.
Frontiers in immunology
Tang T,Li P,Zhou X,Wang R,Fan X,Yang M,Qi K
Wed Jan 05 00:00:00 EST 2022
Hesperetin Exhibits Anti-Inflammatory Effects on Chondrocytes via the AMPK Pathway to Attenuate Anterior Cruciate Ligament Transection-Induced Osteoarthritis.
Frontiers in pharmacology
Wu J,Qian Y,Chen C,Feng F,Pan L,Yang L,Wang C
Tue Oct 05 00:00:00 EDT 2021
Exosome-Derived LncRNA TCONS_00072128 Mediated Osteogenic Differentiation and Inflammation by Caspase 8 Regulation.
Frontiers in genetics
Yang Y,Miao L,Chang S,Zhang Q,Yu L,He P,Zhang Y,Fan W,Liu J,Hao X
Tue Mar 22 00:00:00 EDT 2022
An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism.
Frontiers in pharmacology
Gao Y,Shi W,Yao H,Ai Y,Li R,Wang Z,Liu T,Dai W,Xiao X,Zhao J,Niu M,Bai Z
Tue Oct 12 00:00:00 EDT 2021
An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism.
Frontiers in pharmacology
Gao Y,Shi W,Yao H,Ai Y,Li R,Wang Z,Liu T,Dai W,Xiao X,Zhao J,Niu M,Bai Z
Tue Oct 12 00:00:00 EDT 2021
CCL24 Protects Renal Function by Controlling Inflammation in Podocytes.
Disease markers
Wang Y,Wu X,Geng M,Ding J,Lv K,Du H,Ding J,Pei W,Hu X,Gu J,Wang L,Zhang Y,Gao J
Mon Dec 06 00:00:00 EST 2021
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Scientific reports
Zhao Y,Liu X,Zheng Y,Liu W,Ding C
Mon Oct 18 00:00:00 EDT 2021
Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.
Emerging microbes & infections
Xu L,Lin L,Lu X,Xiao P,Liu R,Wu M,Jin M,Zhang A
Wed Dec 01 00:00:00 EST 2021
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer.
International journal of biological sciences
Yan H,Luo B,Wu X,Guan F,Yu X,Zhao L,Ke X,Wu J,Yuan J
Wed Mar 16 00:00:00 EDT 2022
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer.
International journal of biological sciences
Yan H,Luo B,Wu X,Guan F,Yu X,Zhao L,Ke X,Wu J,Yuan J
Wed Mar 16 00:00:00 EDT 2022
Low-intensity pulsed ultrasound inhibits IL-6 in subchondral bone of temporomandibular joint osteoarthritis by suppressing the TGF-β1/Smad3 pathway.
Archives of oral biology
Yi X,Liu J,Cheng MS,Zhou Q
Sat May 01 00:00:00 EDT 2021
Low-intensity pulsed ultrasound inhibits IL-6 in subchondral bone of temporomandibular joint osteoarthritis by suppressing the TGF-β1/Smad3 pathway.
Archives of oral biology
Yi X,Liu J,Cheng MS,Zhou Q
Sat May 01 00:00:00 EDT 2021
Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis.
Aging
Han Z,Wang H,Guo D,Zhang J
Mon Feb 01 00:00:00 EST 2021
PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma.
Cell death & disease
Xia T,Liu M,Zhao Q,Ouyang J,Xu P,Chen B
Thu Sep 16 00:00:00 EDT 2021
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Food & function
Qu L,Fu R,Ma X,Fan D
Mon Oct 04 00:00:00 EDT 2021
Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.
Scientific reports
Cai GL,Yang ZX,Guo DY,Hu CB,Yan ML,Yan J
Wed Feb 03 00:00:00 EST 2021
Pterocephin A, a novel Triterpenoid Saponin from Pterocephalus hookeri induced liver injury by activation of necroptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang R,Wei L,Dong Z,Meng F,Wang G,Zhou S,Lan X,Liao Z,Chen M
Sat May 01 00:00:00 EDT 2021
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Biochemical and biophysical research communications
Zhang Z,Zhou X,Liu J,Zheng Y,Wu Y,Yang W,Yi Y,Liu J,Wang J
Fri Oct 08 00:00:00 EDT 2021
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Biochemical and biophysical research communications
Zhang Z,Zhou X,Liu J,Zheng Y,Wu Y,Yang W,Yi Y,Liu J,Wang J
Fri Oct 08 00:00:00 EDT 2021
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Biomaterials
Schoenenberger AD,Tempfer H,Lehner C,Egloff J,Mauracher M,Bird A,Widmer J,Maniura-Weber K,Fucentese SF,Traweger A,Silvan U,Snedeker JG
Sat Aug 01 00:00:00 EDT 2020
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
BMJ open diabetes research & care
Yang X,Yang R,Chen M,Zhou Q,Zheng Y,Lu C,Bi J,Sun W,Huang T,Li L,Gong J,Li X,Hui Q,Wang X
Fri May 01 00:00:00 EDT 2020
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
Oxidative medicine and cellular longevity
He XM,Zhou YZ,Sheng S,Li JJ,Wang GQ,Zhang F
Tue Jun 08 00:00:00 EDT 2021
Glimepiride and glibenclamide have comparable efficacy in treating acute ischemic stroke in mice.
Neuropharmacology
Wang X,Chang Y,He Y,Lyu C,Li H,Zhu J,Liu K,Hu Y,Huang K,Pan S
Wed Jan 01 00:00:00 EST 2020
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Neuroscience
Lu Z,Zhang D,Cui K,Fu X,Man J,Lu H,Yu L,Gao Y,Liu X,Liao L,Li X,Liu C,Zhang Y,Zhang Z,Wang J
Tue Jan 21 00:00:00 EST 2020
The P2Y14 receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
Neurochemistry international
Lin J,Zhang YY,Liu F,Fang XY,Liu MK,Huang CL,Wang H,Liao DQ,Zhou C,Shen JF
Sun Dec 01 00:00:00 EST 2019
Dioscin Attenuates Myocardial Damages in Diabetic Rats maybe by Regulating NO-sGC-cGMP-PKG Pathway.
Annals of clinical and laboratory science
Wei Q,Zhu T,Xiao X,Sun L,Zhang Z,Huang T
Tue Jan 01 00:00:00 EST 2019
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Neuroscience
Wang G,Zhou Y,Wang Y,Li D,Liu J,Zhang F
Sun Sep 01 00:00:00 EDT 2019
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Neuroscience
Wang G,Zhou Y,Wang Y,Li D,Liu J,Zhang F
Sun Sep 01 00:00:00 EDT 2019
Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
Investigative ophthalmology & visual science
Wang N,Zou C,Zhao S,Wang Y,Han C,Zheng Z
Wed Aug 01 00:00:00 EDT 2018
Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
Investigative ophthalmology & visual science
Wang N,Zou C,Zhao S,Wang Y,Han C,Zheng Z
Wed Aug 01 00:00:00 EDT 2018