Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
H00003589-M17
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1F1
Immunogen
IL11 (NP_000632.1, 25 a.a. approximately 74 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: PPGPPRVSPD PRAELDSTVL LTRSLLADTR QLAAQLRDKF PADGDHNLDS
Target Information
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Adipogenesis inhibitory factor; AGIF; il 11; IL-11; IL-11ra; IL10RA; IL11 inhibitor; ILN; Interleukin; Interleukin-11; Interleukin11; MGC2146; oprelvekin
Gene Aliases: AGIF; IL-11; IL11
UniProt ID: (Human) P20809
Entrez Gene ID: (Human) 3589
cell-cell signaling
positive regulation of cell proliferation
B cell differentiation
megakaryocyte differentiation
positive regulation of peptidyl-serine phosphorylation
positive regulation of MAPK cascade
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of hormone secretion
positive regulation of peptidyl-tyrosine phosphorylation
regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support