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IL17RB Antibody (MA5-24360) in Flow
Flow cytometry of IL17RB in HEK293 human embryonic kidney cell line transfected with mouse IL-17 RB (panel A) or HEK293 cell line with irrelevant transfectant (panel B). Samples were incubated in IL17RB monoclonal antibody (Product # MA5-24360) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody.
Product Details
MA5-24360
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
752101
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-17RB Arg18-Gly286
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2577151
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-17 RB, rhIL-17 R, or recombinant mouse IL-17 is observed.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ecotropic viral integration site 27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17ER; IL-17RB; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; ZCYTO7
Gene Aliases: Evi27; IL-17ER; IL-17Rh1; Il17br; Il17rb; IL17RH1
UniProt ID: (Mouse) Q9JIP3
Entrez Gene ID: (Mouse) 50905
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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