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Product Details
PA5-53891
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human IL17RE. Recombinant protein control fragment (Product #RP-90384).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642689
Product Specific Information
Immunogen sequence: EKSHHISIPS PDISHKGLRS KRTQPSDPET WESLPRLDSQ RHGGPEFSFD LLPEARAIRV TISSGPEVSV RLCHQWALEC EELSSPYDVQ KIVSGGHTVE LPYEFLLPCL CMEASYLQED TVRRKKCPFQ SWPEAYGSDF WKSVHFTDYS
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 75%.
Target Information
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IL-17 receptor E; Interleukin-17 receptor E
Gene Aliases: IL17RE; UNQ3056/PRO9877
UniProt ID: (Human) Q8NFR9
Entrez Gene ID: (Human) 132014
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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