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Invitrogen
IL18R1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
IL18R1 Antibody (PA5-47954) in WB
Western blot was performed using Anti-IL18R1 Polyclonal Antibody (Product # PA5-47954) and a 62-80 kDa band corresponding to Interleukin-18 receptor 1 was observed across tissue extracts tested and not in Mouse Heart and Mouse Skeletal Muscle which is reported to be low. Tissue extracts (30 µg lysate) of Mouse Heart (Lane 1), Mouse Skeletal Muscle (Lane 2), Mouse Spleen (Lane 3) and Mouse Thymus (Lane 4) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a Nitro... View More
Product Details
PA5-47954
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-18R alpha/IL-1 R5 Ser19-Gly326
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607396
Product Specific Information
In direct ELISAs, approximately 25% cross-reactivity with recombinant human IL-18 R is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD218 antigen-like family member A; CD218a; IL-18R-1; IL-18R-alpha; IL-18R1; IL-1Rrp; IL1 receptor-related protein; IL1R-rp; interleukin 1 receptor related protein; Interleukin-18 receptor 1; Interleukin-18 receptor alpha
Gene Aliases: Il18r1; Il18ralpha; Il1rrp
UniProt ID: (Mouse) Q61098
Entrez Gene ID: (Mouse) 16182
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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