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The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
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Protein Aliases: Accessory protein-like; AcPL; CD218 antigen-like family member B; CD218b; CDw218b; cluster of differentiation w218b; IL-18 RA; IL-18 receptor accessory protein; IL-18 receptor beta; IL-18R-beta; IL-1R accessory protein-like; IL-1R-7; IL-1RAcPL; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta
Gene Aliases: ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RAP; IL18RB; IL1R7
UniProt ID: (Human) O95256
Entrez Gene ID: (Human) 8807
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