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Product Details
PA5-29227
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 342 and 558 of Human IL1 Receptor 1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546703
Product Specific Information
Recommended positive controls: Molt-4, LNCaP.
Predicted reactivity: Mouse (81%), Bovine (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The IL-1 system includes two agonists (IL-1 and IL-1), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; il-1 receptor; il-1r; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; il1 receptor; interleukin 1 receptor alpha, type I; interleukin 1 receptor, type I; interleukin-1 receptor; Interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type I; p80
Gene Aliases: CD121A; D2S1473; IL-1R-alpha; IL1R; IL1R1; IL1RA; IL1RT1; P80
UniProt ID: (Human) P14778
Entrez Gene ID: (Human) 3554
protease binding
signal transducer activity
transmembrane signaling receptor activity
interleukin-1 receptor activity
interleukin-1, Type I, activating receptor activity
platelet-derived growth factor receptor binding
protein binding
ionotropic glutamate receptor binding
transmembrane signal receptor
immune response
cell surface receptor signaling pathway
response to radiation
heat acclimation
ovulation
regulation of inflammatory response
interleukin-1-mediated signaling pathway
response to interleukin-1
response to epidermal growth factor
cellular response to glucose stimulus
response to transforming growth factor beta
response to nitric oxide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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