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Invitrogen
IL1R1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
IL1R1 Antibody (PA5-47937)
Neutralization antibody testing demonstrates the specificity of an antibody through a correlation between antibody binding and the activity of the target. Neutralization of IL-1a/IL-1F1 is shown by decrease in RFU (relative fluorescent units - measure of proliferation) with increasing concentrations of IL-1R polyclonal antibody (PA5-47937) {Neu}
Product Details
PA5-47937
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-1 RI Leu20-Lys338
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609445
Product Specific Information
In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse (rm) IL-18 R is observed and 5% cross-reactivity with rmIL-18 R beta, recombinant human IL-1 RI, and recombinant rat IL-1 Rrp2 is observed and less than 1% cross-reactivity with rmIL-1 RII is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The IL-1 system includes two agonists (IL-1 and IL-1), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; il-1 receptor; IL-1 receptor alpha chain; il-1r; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; il1 receptor; interleukin-1 receptor; Interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type I; p80
Gene Aliases: CD121a; CD121b; IL-1R1; IL-iR; Il1r-1; Il1r1; Il1ra
UniProt ID: (Mouse) P13504
Entrez Gene ID: (Mouse) 16177
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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