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IL1R2 Antibody (PA5-95981) in WB
Western blot analysis of IL1R2 in A-431 cells. Samples were incubated with IL1R2 Polyclonal antibody (Product # PA5-95981) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-95981
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL1R2 (NP_7754651)
Conjugate
Form
Liquid
Concentration
0.62 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807783
Product Specific Information
Immunogen sequence: AHTGAARSCR FRGRHYKREF RLEGEPVALR CPQVPYWLWA SVSPRINLTW HKNDSARTVP GEEETRMWAQ DGALWLLPAL QEDSGTYVCT TRNASYCDKM SIELRVFENT DAFLPFISYP QILTLSTSGV LVCPDLSEFT RDKTDVKIQW YKDSLLLDKD NEKFLSVRGT THLLVHDVAL EDAGYYRCVL TFAHEGQQYN ITRSIELRIK KKKEETIPVI ISPLKTISAS LGSRLTIPCK VFLGTGTPLT TMLWWTANDT HIESAYPGGR VTEGPRQEYS ENNENYIEVP LIFDPVTRED L; Positive Samples: Raji, DU145, HeLa; Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 type II receptor; IL-1R-2; IL-1R-beta; ILR2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type II; type II interleukin-1 receptor, beta
Gene Aliases: CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2; IL1R2c; IL1RB
UniProt ID: (Human) P27930
Entrez Gene ID: (Human) 7850
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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