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Product Details
H00010989-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1A8
Immunogen
IMMT (NP_006830, 481 a.a. approximately 580 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TQLRRQAAAH TDHLRDVLRV QEQELKSEFE QNLSEKLSEQ ELQFRRLSQE QVDNFTLDIN TAYARLRGIE QAVQSHAVAE EEARKAHQLW LSVEALKYSM
Target Information
Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; IMMT antibody; MICOS complex subunit MIC60; mitochondrial inner membrane organizing system 2; Mitochondrial inner membrane protein; Mitofilin; motor protein; p87/89; p87/89 antibody; proliferation-inducing gene 4
Gene Aliases: HMP; IMMT; MIC60; MINOS2; P87; P87/89; P89; PIG4; PIG52
UniProt ID: (Human) Q16891
Entrez Gene ID: (Human) 10989
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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