Product References
Modulation of olfactory-driven behavior by metabolic signals: role of the piriform cortex.
Brain structure & function
Al Koborssy D,Palouzier-Paulignan B,Canova V,Thevenet M,Fadool DA,Julliard AK
AHR0271 was used in Immunocytochemistry-immunoflourescence to investigate if metabolic signaling pathways that are present in the anterior piriform cortex are capable of neuronal modulation and changing complex olfactory behaviors in higher olfactory centers.
Tue Jan 01 00:00:00 EST 2019
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors.
Nature
Hopkins BD,Pauli C,Du X,Wang DG,Li X,Wu D,Amadiume SC,Goncalves MD,Hodakoski C,Lundquist MR,Bareja R,Ma Y,Harris EM,Sboner A,Beltran H,Rubin MA,Mukherjee S,Cantley LC
AHR0271 was used in Immunohistochemistry to study whether insulin feedback induced by phosphatidylinositol-3 kinase inhibitors may reactivate the phosphatidylinositol-3 kinase-mTOR signalling axis in tumours, thereby compromising treatment effectiveness.
Wed Aug 01 00:00:00 EDT 2018
High expression of insulin receptor on tumour-associated blood vessels in invasive bladder cancer predicts poor overall and progression-free survival.
The Journal of pathology
Roudnicky F,Dieterich LC,Poyet C,Buser L,Wild P,Tang D,Camenzind P,Ho CH,Otto VI,Detmar M
AHR0271 was used in immunohistochemistry - paraffin section to find novel biomarkers associated with bladder cancer progression
Thu Jun 01 00:00:00 EDT 2017
A persistent increase in insulin-stimulated glucose uptake by both fast-twitch and slow-twitch skeletal muscles after a single exercise session by old rats.
Age (Dordrecht, Netherlands)
Xiao Y,Sharma N,Arias EB,Castorena CM,Cartee GD
AHR0271 was used in western blot to measure the effects of exercise on glucose uptake by type I (slow-twitch) muscle from old rats.
Sat Jun 01 00:00:00 EDT 2013
Calorie restriction enhances insulin-stimulated glucose uptake and Akt phosphorylation in both fast-twitch and slow-twitch skeletal muscle of 24-month-old rats.
The journals of gerontology. Series A, Biological sciences and medical sciences
Sequea DA,Sharma N,Arias EB,Cartee GD
AHR0271 was used in western blot to examine the insulin signaling pathway in isolated epitrochlearis and soleus muscles of old rats.
Sat Dec 01 00:00:00 EST 2012
Preventing the calorie restriction-induced increase in insulin-stimulated Akt2 phosphorylation eliminates calorie restriction's effect on glucose uptake in skeletal muscle.
Biochimica et biophysica acta
Sharma N,Arias EB,Sequea DA,Cartee GD
AHR0271 was used in western blot to examine the effect of Akt2 phosphorylation on on glucose uptake in skeletal muscle
Thu Nov 01 00:00:00 EDT 2012
A physiological increase of insulin in the olfactory bulb decreases detection of a learned aversive odor and abolishes food odor-induced sniffing behavior in rats.
PloS one
Aimé P,Hegoburu C,Jaillard T,Degletagne C,Garcia S,Messaoudi B,Thevenet M,Lorsignol A,Duchamp C,Mouly AM,Julliard AK
AHR0271 was used in immunohistochemistry - frozen section to study the role of insulin in olfactory function.
Tue Jun 11 00:00:00 EDT 2013
Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats.
American journal of physiology. Endocrinology and metabolism
Sharma N,Arias EB,Bhat AD,Sequea DA,Ho S,Croff KK,Sajan MP,Farese RV,Cartee GD
AHR0271 was used in Western Blot to study the mechanisms behind calorie restriction, improved insulin-stimulated glucose uptake and Akt phosphorylation in skeletal muscle.
Wed Jun 01 00:00:00 EDT 2011
Generation of intracellular domain of insulin receptor tyrosine kinase by gamma-secretase.
Biochemical and biophysical research communications
Kasuga K,Kaneko H,Nishizawa M,Onodera O,Ikeuchi T
AHR0271 was used in western blot to test if the insulin receptor undergoes presenilin/gamma-secretase-dependent processing
Fri Aug 17 00:00:00 EDT 2007
In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase.
Cancer cell
García-Echeverría C,Pearson MA,Marti A,Meyer T,Mestan J,Zimmermann J,Gao J,Brueggen J,Capraro HG,Cozens R,Evans DB,Fabbro D,Furet P,Porta DG,Liebetanz J,Martiny-Baron G,Ruetz S,Hofmann F
AHR0271 was used in ELISA to study the in vivo antitumor activity of a potent and selective IGF-1 receptor kinase inhibitor
Mon Mar 01 00:00:00 EST 2004