Product References
TUG-891 inhibits neuronal endoplasmic reticulum stress and pyroptosis activation and protects neurons in a mouse model of intraventricular hemorrhage.
Neural regeneration research
Wang HX,Liu C,Li YY,Cao Y,Zhao L,Zhao YJ,Deng ZA,Tong AP,Zhou LX
Sun Oct 01 00:00:00 EDT 2023
1,25(OH)2 D3 induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Cellular signalling
Erzurumlu Y,Aydogdu E,Dogan HK,Catakli D,Muhammed MT,Buyuksandic B
Wed Mar 01 00:00:00 EST 2023
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Molecular oncology
Luo G,Aldridge K,Chen T,Aslot V,Kim BG,Han EH,Singh N,Li S,Xiao TS,Sporn MB,Letterio JJ
Fri Dec 01 00:00:00 EST 2023
Metastatic effects of environmental carcinogens mediated by MAPK and UPR pathways with an in vivo Drosophila Model.
Journal of hazardous materials
Fangninou FF,Yu Z,Li Z,Guadie A,Li W,Xue L,Yin D
Thu Jan 05 00:00:00 EST 2023
IRAK2 Downregulation in Triple-Negative Breast Cancer Cells Decreases Cellular Growth In Vitro and Delays Tumour Progression in Murine Models.
International journal of molecular sciences
Ferraro F,Steinle A,Narasimhan H,Bleilevens A,Stolzenberg PM,Braunschweig T,Stickeler E,Maurer J
Sat Jan 28 00:00:00 EST 2023
Citrinin Exposure Induced Testicular Damage and Spermatogenesis Disorder by Triggering Endoplasmic Reticulum Stress.
Foods (Basel, Switzerland)
Wu J,Wu Y,Fan H,Yang C,Yang M,Kong X,Ning C,Wang S,Xiao W,Wang N,Yi J,Yuan Z
Tue Apr 11 00:00:00 EDT 2023
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Life sciences
Zhou X,Li Y,Yang C,Chen D,Wang T,Liu T,Yan W,Su Z,Peng B,Ren X
Tue Aug 15 00:00:00 EDT 2023
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Redox biology
Wang Z,Tan C,Duan C,Wu J,Zhou D,Hou L,Qian W,Han C,Hou X
Sat Apr 01 00:00:00 EDT 2023
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Advanced healthcare materials
Mo W,Liu S,Zhao X,Wei F,Li Y,Sheng X,Cao W,Ding M,Zhang W,Chen X,Meng L,Yao S,Diao W,Wei H,Guo H
Tue Aug 01 00:00:00 EDT 2023
Identification of indocyanine green as a STT3B inhibitor against mushroom α-amanitin cytotoxicity.
Nature communications
Wang B,Wan AH,Xu Y,Zhang RX,Zhao BC,Zhao XY,Shi YC,Zhang X,Xue Y,Luo Y,Deng Y,Neely GG,Wan G,Wang QP
Tue May 16 00:00:00 EDT 2023
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Cellular signalling
Erzurumlu Y,Muhammed MT
Fri Sep 01 00:00:00 EDT 2023
Nobiletin inhibits de novo FA synthesis to alleviate gastric cancer progression by regulating endoplasmic reticulum stress.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen M,Zhang R,Chen Y,Chen X,Li Y,Shen J,Yuan M,Chen Y,Wu J,Sun Q
Tue Jul 25 00:00:00 EDT 2023
Dexamethasone-stimulated glucocorticoid receptor signaling positively regulates the endoplasmic reticulum-associated degradation (ERAD) mechanism in hepatocellular carcinoma cells.
Steroids
Erzurumlu Y,Dogan HK,Cataklı D
Sat Jul 01 00:00:00 EDT 2023
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Journal of natural medicines
Erzurumlu Y,Catakli D,Dogan HK
Thu Jun 01 00:00:00 EDT 2023
Persistent Lipid Accumulation Leads to Persistent Exacerbation of Endoplasmic Reticulum Stress and Inflammation in Progressive NASH via the IRE1α/TRAF2 Complex.
Molecules (Basel, Switzerland)
Lei N,Song H,Zeng L,Ji S,Meng X,Zhu X,Li X,Feng Q,Liu J,Mu J
Mon Apr 03 00:00:00 EDT 2023
Persistent Lipid Accumulation Leads to Persistent Exacerbation of Endoplasmic Reticulum Stress and Inflammation in Progressive NASH via the IRE1α/TRAF2 Complex.
Molecules (Basel, Switzerland)
Lei N,Song H,Zeng L,Ji S,Meng X,Zhu X,Li X,Feng Q,Liu J,Mu J
Mon Apr 03 00:00:00 EDT 2023
Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.
Molecular biology reports
Erzurumlu Y,Dogan HK,Catakli D
Wed Feb 01 00:00:00 EST 2023
Thrombospondin-1 mimic peptide PKHB1 induced endoplasmic reticulum stress-mediated but CD47-independent apoptosis in non-small cell lung cancer.
Drug development research
Ye J,Yao Y,Zhao J,Cui L,Lu G,Wang Q,Zhang P,Zhou J
Sat Apr 01 00:00:00 EDT 2023
Balanced mitochondrial and cytosolic translatomes underlie the biogenesis of human respiratory complexes.
Genome biology
Soto I,Couvillion M,Hansen KG,McShane E,Moran JC,Barrientos A,Churchman LS
Tue Aug 09 00:00:00 EDT 2022
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Cell death & disease
Wang R,Shang Y,Chen B,Xu F,Zhang J,Zhang Z,Zhao X,Wan X,Xu A,Wu L,Zhao G
Thu Oct 06 00:00:00 EDT 2022
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Brain and behavior
Liu H,He S,Li C,Wang J,Zou Q,Liao Y,Chen R
Thu Dec 01 00:00:00 EST 2022
Di(2-ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study.
Environmental toxicology
Xu Q,Zhao T,Ri H,Ye J,Zhao W,Zhang Y,Ye L
Thu Dec 01 00:00:00 EST 2022
Mitochondrial oxidative phosphorylation is dispensable for survival of CD34+ chronic myeloid leukemia stem and progenitor cells.
Cell death & disease
Yan JS,Yang MY,Zhang XH,Luo CH,Du CK,Jiang Y,Dong XJ,Wang ZM,Yang LX,Li YD,Xia L,Lu Y
Wed Apr 20 00:00:00 EDT 2022
sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes.
Life sciences
Zhu L,Li B,Chen D,Chen N,Xu L,Li Q,Chen X
Sun May 01 00:00:00 EDT 2022
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
PeerJ
Zhang L,Li C,Fu L,Yu Z,Xu G,Zhou J,Shen M,Feng Z,Zhu H,Xie T,Zhou L,Zhou X
Fri Jan 06 00:00:00 EST 2023
Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis.
Cell stem cell
Li C,Wu B,Li Y,Chen J,Ye Z,Tian X,Wang J,Xu X,Pan S,Zheng Y,Cai X,Jiang L,Zhao M
Thu Jul 07 00:00:00 EDT 2022
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
Metabolites
Yan Y,Huang J,Huan C,Li L,Li C
Sat Aug 27 00:00:00 EDT 2022
Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy.
Biomedicines
Malik A,Bagchi AK,Jassal DS,Singal PK
Wed Apr 13 00:00:00 EDT 2022
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
eLife
Ramani K,Mavila N,Abeynayake A,Tomasi ML,Wang J,Matsuda M,Seki E
Tue Oct 04 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin.
Ecotoxicology and environmental safety
Wang J,Ding L,Wang K,Huang R,Yu W,Yan B,Wang H,Zhang C,Yang Z,Liu Z
Mon Aug 01 00:00:00 EDT 2022
Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury.
Experimental neurology
Li L,Luo Q,Shang B,Yang X,Zhang Y,Pan Q,Wu N,Tang W,Du D,Sun X,Jiang L
Sat Jan 01 00:00:00 EST 2022
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Journal of virology
Shi J,Li Z,Xu R,Zhang J,Zhou Q,Gao R,Lu H,Lan Y,Zhao K,He H,Gao F,He W
Wed Jan 12 00:00:00 EST 2022
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Frontiers in pharmacology
Qin K,Tang H,Ren Y,Yang D,Li Y,Huang W,Wu Y,Yin Z
Tue Aug 30 00:00:00 EDT 2022
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Frontiers in pharmacology
Qin K,Tang H,Ren Y,Yang D,Li Y,Huang W,Wu Y,Yin Z
Tue Aug 30 00:00:00 EDT 2022
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
Cellular & molecular biology letters
Liu P,Zu F,Chen H,Yin X,Tan X
Sat Oct 08 00:00:00 EDT 2022
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats.
Experimental biology and medicine (Maywood, N.J.)
Yang R,Chen J,Jia Q,Yang X,Mehmood S
Mon Aug 01 00:00:00 EDT 2022
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Nutrients
Zhong Y,Li Z,Jin R,Yao Y,He S,Lei M,Wang X,Shi C,Gao L,Peng X
Thu Nov 24 00:00:00 EST 2022
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Nutrients
Zhong Y,Li Z,Jin R,Yao Y,He S,Lei M,Wang X,Shi C,Gao L,Peng X
Thu Nov 24 00:00:00 EST 2022
Icariin attenuates ischaemic stroke through suppressing inflammation mediated by endoplasmic reticulum stress signalling pathway in rats.
Clinical and experimental pharmacology & physiology
Zheng J,Liao Y,Xu Y,Mo Z
Fri Jul 01 00:00:00 EDT 2022
Huaier Induces Immunogenic Cell Death Via CircCLASP1/PKR/eIF2α Signaling Pathway in Triple Negative Breast Cancer.
Frontiers in cell and developmental biology
Li C,Wang X,Chen T,Li W,Zhou X,Wang L,Yang Q
Sat Jul 16 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
Toxics
Wang P,Liu D,Yan S,Liang Y,Cui J,Guo L,Ren S,Chen P
Fri Jul 29 00:00:00 EDT 2022
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Food & function
Liu Y,Huang H,Xu Z,Xue Y,Zhang D,Zhang Y,Li W,Li X
Mon Mar 07 00:00:00 EST 2022
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Food & function
Zhong Y,Liu J,Sun D,Guo T,Yao Y,Xia X,Shi C,Peng X
Mon Mar 21 00:00:00 EDT 2022
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Journal of hazardous materials
Zhu Q,Liu Z,Wang Y,Song E,Song Y
Sat Jun 05 00:00:00 EDT 2021
Near-infrared emission Cu, N-doped carbon dots for human umbilical vein endothelial cell labeling and their biocompatibility in vitro.
Journal of applied toxicology : JAT
Zhu P,Zhang T,Li J,Ma J,Ouyang X,Zhao X,Xu M,Wang D,Xu Q
Sat May 01 00:00:00 EDT 2021
Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.
Frontiers in pharmacology
Liu Z,Liao T,Yang N,Ding L,Li X,Wu P,Wang P
Tue Sep 21 00:00:00 EDT 2021
Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.
Journal of applied toxicology : JAT
Cheng X,Guo H,Xian Y,Xie X
Sat May 01 00:00:00 EDT 2021
Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
NanoImpact
Liu Y,Hu Q,Huang C,Cao Y
Thu Jul 01 00:00:00 EDT 2021
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Journal of biochemical and molecular toxicology
Zhou X,Zhang X,Wu Z,Xu X,Guo M,Zhai X,Zuo D,Wu Y
Mon Mar 01 00:00:00 EST 2021
PM2.5 exposure induces reproductive injury through IRE1/JNK/autophagy signaling in male rats.
Ecotoxicology and environmental safety
Yang Y,Feng Y,Huang H,Cui L,Li F
Mon Mar 15 00:00:00 EDT 2021
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis.
Cell biology and toxicology
Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Peng X
Fri Oct 01 00:00:00 EDT 2021
Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons.
EBioMedicine
Arioka Y,Shishido E,Kushima I,Suzuki T,Saito R,Aiba A,Mori D,Ozaki N
Fri Jan 01 00:00:00 EST 2021
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.
Journal of neuroinflammation
Liu T,Li T,Chen X,Li Z,Feng M,Yao W,Wan L,Zhang C,Zhang Y
Thu Sep 16 00:00:00 EDT 2021
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca2+ Homeostasis, and Bcl2 Expression.
Molecular nutrition & food research
Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Zhang Y,Peng X
Sun Aug 01 00:00:00 EDT 2021
Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria.
Cell
Yang R,Mele F,Worley L,Langlais D,Rosain J,Benhsaien I,Elarabi H,Croft CA,Doisne JM,Zhang P,Weisshaar M,Jarrossay D,Latorre D,Shen Y,Han J,Ogishi M,Gruber C,Markle J,Al Ali F,Rahman M,Khan T,Seeleuthner Y,Kerner G,Husquin LT,Maclsaac JL,Jeljeli M,Errami A,Ailal F,Kobor MS,Oleaga-Quintas C,Roynard M,Bourgey M,El Baghdadi J,Boisson-Dupuis S,Puel A,Batteux F,Rozenberg F,Marr N,Pan-Hammarström Q,Bogunovic D,Quintana-Murci L,Carroll T,Ma CS,Abel L,Bousfiha A,Di Santo JP,Glimcher LH,Gros P,Tangye SG,Sallusto F,Bustamante J,Casanova JL
Wed Dec 23 00:00:00 EST 2020
Ambroxol Improves Neuronal Survival and Reduces White Matter Damage through Suppressing Endoplasmic Reticulum Stress in Microglia after Intracerebral Hemorrhage.
BioMed research international
Jiang X,Zhang J,Kou B,Zhang C,Zhong J,Fang X,Huang X,Zhang X,Xie F,Hu Q,Ge H,Yu A
Mon Jan 11 00:00:00 EST 2021
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Redox biology
Wang Y,Chen J,Li S,Zhang X,Guo Z,Hu J,Shao X,Song N,Zhao Y,Li H,Yang G,Xu C,Wei C
Fri May 01 00:00:00 EDT 2020
Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats.
World journal of gastroenterology
Su W,Tai Y,Tang SH,Ye YT,Zhao C,Gao JH,Tuo BG,Tang CW
Tue Jul 28 00:00:00 EDT 2020
Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway.
Oxidative medicine and cellular longevity
Zhang L,Cai S,Cao S,Nie J,Zhou W,Zhang Y,Li K,Wang H,Yu S,Yu T
Fri May 14 00:00:00 EDT 2021
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Life sciences
Fu J,Nchambi KM,Wu H,Luo X,An X,Liu D
Wed Jul 01 00:00:00 EDT 2020
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Environmental science and pollution research international
Sun S,Ji Z,Fu J,Wang XF,Zhang LS
Wed Jul 01 00:00:00 EDT 2020
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
Frontiers in neuroscience
He M,Qian K,Zhang Y,Huang XF,Deng C,Zhang B,Gao G,Li J,Xie H,Sun T
Tue Feb 16 00:00:00 EST 2021
Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress.
Frontiers in pharmacology
Mai X,Yin X,Chen P,Zhang M
Sat Jan 02 00:00:00 EST 2021
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Cell cycle (Georgetown, Tex.)
Song Q,He Z,Li B,Liu J,Liu L,Liao W,Xiong Y,Song C,Yang S,Liu Y
Thu Oct 01 00:00:00 EDT 2020
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
International journal of nanomedicine
Sun Y,Gong J,Cao Y
Thu Feb 20 00:00:00 EST 2020
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Life sciences
Wu T,Jiang N,Ji Z,Shi G
Thu Aug 15 00:00:00 EDT 2019
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Life sciences
Wu T,Jiang N,Ji Z,Shi G
Thu Aug 15 00:00:00 EDT 2019
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Life sciences
Wu T,Jiang N,Ji Z,Shi G
Thu Aug 15 00:00:00 EDT 2019
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Environmental pollution (Barking, Essex : 1987)
Hou Y,Fu J,Sun S,Jin Y,Wang X,Zhang L
Tue Oct 01 00:00:00 EDT 2019
