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Product Details
TA503382
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1G3
Immunogen
Full length human recombinant protein of human IRF6 produced in HEK293 cell.
Conjugate
Form
Liquid
Concentration
0.73 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Interferon regulatory factor 6; IRF-6
Gene Aliases: IRF6; LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
UniProt ID: (Human) O14896
Entrez Gene ID: (Human) 3664
transcription, DNA-templated
cell cycle arrest
negative regulation of cell proliferation
keratinocyte differentiation
keratinocyte proliferation
positive regulation of transcription, DNA-templated
cell development
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
mammary gland epithelial cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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