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In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant human (rh) Integrin alpha 8 is observed, and less than 1% cross-reactivity with rhIntegrin alpha 5, recombinant mouse (rm) Integrin alpha 5, rhIntegrin alpha V and rmIntegrin alpha V is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Integrin alpha-8
Gene Aliases: AI447669; Itga8; RGD1564327
UniProt ID: (Mouse) A2ARA8
Entrez Gene ID: (Mouse) 241226, (Rat) 364786
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