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Product Details
PA5-47331
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Iduronate 2-Sulfatase/IDS Thr36-Pro552
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608040
Product Specific Information
In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human IDS is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-L-iduronate sulfate sulfatase; Iduronate 2-sulfatase; iduronate sulfatase; iduronate-2-sulfatase
Gene Aliases: AW214631; Ids
UniProt ID: (Mouse) Q08890
Entrez Gene ID: (Mouse) 15931
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