Product References
Exercise induced meteorin-like protects chondrocytes against inflammation and pyroptosis in osteoarthritis by inhibiting PI3K/Akt/NF-κB and NLRP3/caspase-1/GSDMD signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu J,Jia S,Yang Y,Piao L,Wang Z,Jin Z,Bai L
Wed Feb 01 00:00:00 EST 2023
VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection.
Cell reports
Qi L,Li X,Zhang F,Zhu X,Zhao Q,Yang D,Hao S,Li T,Li X,Tian T,Feng J,Sun X,Wang X,Gao S,Wang H,Ye J,Cao S,He Y,Wang H,Wei B
Tue May 30 00:00:00 EDT 2023
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Chinese journal of natural medicines
Teng L,Shen Y,Qu Y,Yang L,Yang Y,Jian X,Fan S,Zhang L,Fu Q
Wed Feb 01 00:00:00 EST 2023
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Cancers
Wang Q,Lei Z,Wang Z,Jiang Q,Zhang Z,Liu X,Xing B,Li S,Guo X,Liu Y,Li X,Shu K,Zhang H,Huang Y,Lei T
Mon Mar 06 00:00:00 EST 2023
Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration.
Bioactive materials
Sun J,Yang F,Wang L,Yu H,Yang Z,Wei J,Vasilev K,Zhang X,Liu X,Zhao Y
Mon May 01 00:00:00 EDT 2023
Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Wang N,Jiang D,Zhou C,Han X
Tue Aug 01 00:00:00 EDT 2023
PDK1-stabilized LncRNA SPRY4-IT1 promotes breast cancer progression via activating NF-κB signaling pathway.
Molecular carcinogenesis
Zhang Y,Chen H,Yuan R,Wang Y,Zhang D,Zeng Q,Jiang W,Zhang R,Chen T,Chai C,Guo B
Sat Jul 01 00:00:00 EDT 2023
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Cell & bioscience
Gu G,Zhu B,Ren J,Song X,Fan B,Ding H,Shang J,Wu H,Li J,Wang H,Li J,Wei Z,Feng S
Sat Feb 04 00:00:00 EST 2023
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Nephrology (Carlton, Vic.)
Liu Z,Xiang H,Deng Q,Fu W,Li Y,Yu Z,Qiu Y,Mei Z,Xu L
Thu Jun 01 00:00:00 EDT 2023
Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis.
Molecular therapy : the journal of the American Society of Gene Therapy
Lian J,Zhu X,Du J,Huang B,Zhao F,Ma C,Guo R,Zhang Y,Ji L,Yahaya BH,Lin J
Wed May 03 00:00:00 EDT 2023
Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy.
Clinical science (London, England : 1979)
Gong W,Jiao Q,Yuan J,Luo H,Liu Y,Zhang Y,Chen Z,Xu X,Bai L,Zhang X
Fri Mar 31 00:00:00 EDT 2023
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
Regenerative biomaterials
You S,Zhu Y,Li H,He F,Liu S,Yang X,Wang L,Zeng H,Dai J,Hu L
Tue May 02 00:00:00 EDT 2023
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Molecular and cellular biochemistry
Gao J,Zhou J,Zhang M,Zhang Y,Zeng Y,Li S,Xu K,Yao R
Fri May 19 00:00:00 EDT 2023
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Molecular and cellular biochemistry
Gao J,Zhou J,Zhang M,Zhang Y,Zeng Y,Li S,Xu K,Yao R
Fri May 19 00:00:00 EDT 2023
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Molecular and cellular biochemistry
Gao J,Zhou J,Zhang M,Zhang Y,Zeng Y,Li S,Xu K,Yao R
Fri May 19 00:00:00 EDT 2023
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Molecular and cellular biochemistry
Gao J,Zhou J,Zhang M,Zhang Y,Zeng Y,Li S,Xu K,Yao R
Fri May 19 00:00:00 EDT 2023
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Transplantation and cellular therapy
Wang X,Zhou Y,Sun Q,Zhang Q,Zhou H,Zhang J,Du Y,Wang Y,Yuan K,Xu L,Zhang M,Yan D,Zeng L,Xu K,Sang W
Tue Aug 01 00:00:00 EDT 2023
Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.
Archives of biochemistry and biophysics
Xie BW,Guan B,Chen W,Zhou M,Gu Q,Liu Y,Yan D
Thu Jun 01 00:00:00 EDT 2023
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.
Acta pharmacologica Sinica
Yang DG,Gao YY,Yin ZQ,Wang XR,Meng XS,Zou TF,Duan YJ,Chen YL,Liao CZ,Xie ZL,Fan XD,Sun L,Han JH,Yang XX
Wed Feb 01 00:00:00 EST 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
Foods (Basel, Switzerland)
Zhao L,Miao Y,Shan B,Zhao C,Peng C,Gong J
Thu Mar 30 00:00:00 EDT 2023
Anti-inflammatory labdane diterpenoids from the aerial parts of Leonurus japonicus.
Phytochemistry
Wei QH,Cao XX,Xu DF,Wang ST,Zhang JS,Zhang H
Thu Jun 01 00:00:00 EDT 2023
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Frontiers in bioengineering and biotechnology
Ge L,Wang K,Lin H,Tao E,Xia W,Wang F,Mao C,Feng Y
Tue Mar 21 00:00:00 EDT 2023
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
International immunopharmacology
Shi X,Wu Y,Ni H,Li M,Qi B,Xu Y
Wed Feb 01 00:00:00 EST 2023
YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis.
Cell reports
Fang Q,Tian GG,Wang Q,Liu M,He L,Li S,Wu J
Tue Apr 25 00:00:00 EDT 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 EST 2023
Oral administration of Lactobacillus plantarum JC7 alleviates OVA-induced murine food allergy through immunoregulation and restoring disordered intestinal microbiota.
European journal of nutrition
Duan C,Ma L,Yu J,Sun Y,Liu L,Ma F,Li X,Li D
Wed Mar 01 00:00:00 EST 2023
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Cell cycle (Georgetown, Tex.)
Zhu J,Sun R,Yan C,Sun K,Gao L,Zheng B,Shi J
Mon May 01 00:00:00 EDT 2023
Trans-anethole exerts protective effects on lipopolysaccharide-induced acute jejunal inflammation of broilers via repressing NF-κB signaling pathway.
Poultry science
Tong Y,Yu C,Chen S,Zhang X,Yang Z,Wang T
Wed Feb 01 00:00:00 EST 2023
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1.
Acta pharmacologica Sinica
Wang ZW,Zou FM,Wang AL,Yang J,Jin R,Wang BL,Shen LJ,Qi S,Liu J,Liu J,Wang WC,Liu QS
Sat Apr 01 00:00:00 EDT 2023
Phenylalanine diminishes M1 macrophage inflammation.
Science China. Life sciences
Zhang Q,Chen S,Guo Y,He F,Fu J,Ren W
Fri Dec 01 00:00:00 EST 2023
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Huang H,Li X,Zha D,Lin H,Yang L,Wang Y,Xu L,Wang L,Lei T,Zhou Z,Xiao YF,Xin HB,Fu M,Qian Y
Tue Aug 01 00:00:00 EDT 2023
Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells.
Frontiers in endocrinology
Shi X,Zhang W,Bao X,Liu X,Yang M,Yin C
Mon Mar 20 00:00:00 EDT 2023
Syndecan-3 Coregulates Milk Fat Metabolism and Inflammatory Reactions in Bovine Mammary Epithelial Cells through AMPK/SIRT1 Signaling Pathway.
International journal of molecular sciences
Fan J,Zhao Z,Wu H,Fang X,Miao F,Chen X,Jiang X,Li J,Jiang P,Yu H
Mon Apr 03 00:00:00 EDT 2023
Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.
Heliyon
Liu B,Su H
Wed Feb 01 00:00:00 EST 2023
The NF-κB pathway plays a vital role in rat salivary gland atrophy model.
Heliyon
Yang Y,Zi Y,Conglin D,Chunmei Z,Liang H,Songlin W
Wed Mar 01 00:00:00 EST 2023
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Inflammation
Li K,Feng Z,Wang L,Ma X,Wang L,Liu K,Geng X,Peng C
Thu Jun 01 00:00:00 EDT 2023
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Biomolecules
Cornwell A,Ziółkowski H,Badiei A
Sat Apr 29 00:00:00 EDT 2023
Analyses of Transcriptomics upon IL-1β-Stimulated Mouse Chondrocytes and the Protective Effect of Catalpol through the NOD2/NF-κB/MAPK Signaling Pathway.
Molecules (Basel, Switzerland)
Pang Y,Zhao L,Ji X,Guo K,Yin X
Tue Feb 07 00:00:00 EST 2023
Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress.
Cardiovascular drugs and therapy
Zhang L,Hu C,Jin B,Bai B,Liao J,Jin L,Wang M,Zhu W,Wu X,Zheng L,Xu X,Jiang Y,Wang Y,He Y
Fri Jan 20 00:00:00 EST 2023
A short peptide exerts neuroprotective effects on cerebral ischemia-reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis.
Journal of neuroinflammation
Li Y,Jin T,Liu N,Wang J,Qin Z,Yin S,Zhang Y,Fu Z,Wu Y,Wang Y,Liu Y,Yang M,Pang A,Sun J,Wang Y,Yang X
Tue Feb 28 00:00:00 EST 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 EDT 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 EDT 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Drug design, development and therapy
Li Y,Zhu S,Luo J,Tong Y,Zheng Y,Ji L,He Z,Jing Q,Huang J,Zhang Y,Bi Q
Thu Jun 01 00:00:00 EDT 2023
Pattern recognition receptor mediated innate immune response requires a Rif-dependent pathway.
Journal of autoimmunity
Tian X,Nanding K,Dai X,Wang Q,Wang J,Fan L
Sun Jan 01 00:00:00 EST 2023
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
International journal of biological macromolecules
Ding Q,Ding C,Liu X,Zheng Y,Zhao Y,Zhang S,Sun S,Peng Z,Liu W
Fri Jun 30 00:00:00 EDT 2023
Feline umbilical cord-derived mesenchymal stem cells: isolation, identification, and antioxidative stress role through NF-κB signaling pathway.
Frontiers in veterinary science
Zhai ZH,Li J,You Z,Cai Y,Yang J,An J,Zhao DP,Wang HJ,Dou MM,Du R,Qin J
Tue Jun 13 00:00:00 EDT 2023
Folic acid ameliorates N-methyl-N'-nitro-N-nitrosoguanidine-induced esophageal inflammation via modulation of the NF-κB pathway.
Toxicology and applied pharmacology
Cheng S,Che L,Yang Q,Sun R,Nie Y,Shi H,Ding Y,Wang L,Du Z,Liu Z
Fri Jul 15 00:00:00 EDT 2022
Endothelial RGS12 governs angiogenesis in inflammatory arthritis by controlling cilia formation and elongation via MYCBP2 signaling.
Cell insight
Yuan G,Yang ST,Yang S
Sat Oct 01 00:00:00 EDT 2022
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Journal of agricultural and food chemistry
Xu D,Zhuang L,Gao S,Ma H,Cheng J,Liu J,Liu D,Fu S,Hu G
Wed Nov 23 00:00:00 EST 2022
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Ecotoxicology and environmental safety
Liu F,Wang Y,Chen L,Bello BK,Zhang T,Yang H,Li X,Pan E,Feng H,Dong J
Sat Oct 01 00:00:00 EDT 2022
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hao M,Ding C,Peng X,Chen H,Dong L,Zhang Y,Chen X,Liu W,Luo Y
Sat Oct 01 00:00:00 EDT 2022
Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages.
Cell death & disease
Cao J,Li L,Yao Y,Xing Y,Ma H
Tue Apr 19 00:00:00 EDT 2022
Fufang Zhenzhu Tiaozhi capsule ameliorates hyperuricemic nephropathy by inhibition of PI3K/AKT/NF-κB pathway.
Journal of ethnopharmacology
Li MH,Guan J,Chen Z,Mo JX,Wu KR,Hu XG,Lan T,Guo J
Tue Nov 15 00:00:00 EST 2022
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Arthritis research & therapy
Yu H,Li M,Wen X,Yang J,Liang X,Li X,Bao X,Shu J,Ren X,Chen W,Li Z,Li Y
Fri Apr 29 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.
Drug design, development and therapy
Liu J,Fan G,Tao N,Feng F,Meng C,Sun T
Tue Jun 21 00:00:00 EDT 2022
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Frontiers in pharmacology
Ling X,Zhou J,Jin T,Xu W,Sun X,Li W,Ding Y,Liang M,Zhu C,Zhao P,Hu C,Yuan B,Xie T,Tao J
Wed Sep 07 00:00:00 EDT 2022
Maternal nucleotide supplementation improves the intestinal morphology and immune function in lipopolysaccharide-challenged newborn piglets.
Frontiers in veterinary science
Li Q,Hung I,Bai K,Wang T
Fri Nov 18 00:00:00 EST 2022
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ding Q,Chen K,Liu X,Ding C,Zhao Y,Sun S,Zhang Y,Zhang J,Liu S,Liu W
Mon Aug 01 00:00:00 EDT 2022
M6A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide.
Antioxidants (Basel, Switzerland)
Xu M,Zhuo R,Tao S,Liang Y,Liu C,Liu Q,Wang T,Zhong X
Fri Sep 30 00:00:00 EDT 2022
MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion.
Nature metabolism
Zhang Y,Zhao M,Gao H,Yu G,Zhao Y,Yao F,Yang W
Tue Mar 01 00:00:00 EST 2022
CX-5461 is a potent immunosuppressant which inhibits T cell-mediated alloimmunity via p53-DUSP5.
Pharmacological research
Pan G,Zhang J,Han Y,Chen Y,Guo X,Cui X,Cheng M,Gao H,Wang J,Jiang F
Tue Mar 01 00:00:00 EST 2022
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Shen Y,Teng L,Qu Y,Liu J,Zhu X,Chen S,Yang L,Huang Y,Song Q,Fu Q
Thu Feb 10 00:00:00 EST 2022
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation.
Immunology letters
Cao DY,Zhang ZH,Li RZ,Shi XK,Xi RY,Zhang GL,Li F,Wang F
Fri Apr 01 00:00:00 EDT 2022
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Oncology letters
Yang L,Liu S,Yang L,Xu B,Wang M,Kong X,Song Z
Sun May 01 00:00:00 EDT 2022
Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.
BMC cardiovascular disorders
Zhuang J,Cheng G,Huang J,Guo H,Lai Y,Wang J,Shan Z,Zheng S
Wed Feb 23 00:00:00 EST 2022
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Wang Z,Liang M,Li H,Liu B,Yang L
Mon Aug 01 00:00:00 EDT 2022
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Journal of ethnopharmacology
Ren X,Xing Y,He L,Xiu Z,Yang L,Han A,Jia Q,Dong Y
Tue May 10 00:00:00 EDT 2022
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
International immunopharmacology
Liang R,Yuan Y,Bai Y,Liu X,Chen J,Jiang D,Meng D,Chen G,Li B,Zhou L,Guo W
Thu Sep 01 00:00:00 EDT 2022
Long noncoding RNA GAS5 alleviates the inflammatory response of human periodontal ligament stem cells by regulating the NF-κB signalling pathway.
European journal of orthodontics
Yang Q,Liu P,Han Y,Wang C,Huang Y,Li X,Zheng Y,Li W
Thu Dec 01 00:00:00 EST 2022
Administration of krill oil extends lifespan of fish Nothobranchius guentheri via enhancement of antioxidant system and suppression of NF-κB pathway.
Fish physiology and biochemistry
Song L,Leng K,Xiao K,Zhang S
Mon Aug 01 00:00:00 EDT 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway.
Peptides
Huang Y,Chen Q,Jiang Q,Zhao Z,Fang J,Chen L
Sat Jan 01 00:00:00 EST 2022
MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST.
PLoS pathogens
Tu Y,Yin XJ,Liu Q,Zhang S,Wang J,Ji BZ,Zhang J,Sun MS,Yang Y,Wang CH,Yin L,Liu Y
Tue Nov 01 00:00:00 EDT 2022
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Frontiers in pharmacology
Ma T,Jia L,Zhao J,Lv L,Yu Y,Ruan H,Song X,Chen H,Li X,Zhang J,Gao L
Fri Nov 18 00:00:00 EST 2022
Trans-Anethole Alleviates Subclinical Necro-Haemorrhagic Enteritis-Induced Intestinal Barrier Dysfunction and Intestinal Inflammation in Broilers.
Frontiers in microbiology
Yu C,Wang D,Tong Y,Li Q,Yang W,Wang T,Yang Z
Fri Apr 08 00:00:00 EDT 2022
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets.
Life sciences
Yao Y,Wang H,Yang Y,Jiang Z,Ma H
Tue Nov 01 00:00:00 EDT 2022
Methylsulfonylmethane ameliorates inflammation via NF-κB and ERK/JNK-MAPK signaling pathway in chicken trachea and HD11 cells during Mycoplasma gallisepticum infection.
Poultry science
Miao Y,Niu D,Wang Z,Wang J,Wu Z,Bao J,Jin X,Li R,Ishfaq M,Li J
Fri Apr 01 00:00:00 EDT 2022
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Frontiers in immunology
Huang D,Wang P,Chen J,Li Y,Zhu M,Tang Y,Zhou W
Mon Nov 21 00:00:00 EST 2022
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li X,Chu L,Liu S,Zhang W,Lin L,Zheng G
Sat Jan 01 00:00:00 EST 2022
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Frontiers in molecular neuroscience
Lu Y,Li B,Xu A,Liang X,Xu T,Jin H,Xie Y,Wang R,Liu X,Gao X,Han Y,Zeng J
Tue Aug 16 00:00:00 EDT 2022
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
Frontiers in oncology
Islam MT,Chen FZ,Chen HC,Wahid A
Tue Nov 08 00:00:00 EST 2022
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
Phytotherapy research : PTR
Mao J,Zhan H,Meng F,Wang G,Huang D,Liao Z,Chen M
Tue Mar 01 00:00:00 EST 2022
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Journal of ethnopharmacology
Zhou GQ,Chen G,Yang J,Qin WY,Ping J
Sun Jan 30 00:00:00 EST 2022
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells.
International immunopharmacology
Yu C,Wang D,Li Q,Tong Y,Yang Z,Wang T
Fri Jul 01 00:00:00 EDT 2022
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway.
Frontiers in oncology
Ning S,Chen Y,Wang G,Liu Y,Yang Y,Zhang Z
Tue May 02 00:00:00 EDT 2023
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Pharmaceutical biology
Tian J,Wang XL,Wang LC,Chen F,Tian Y,Ma L,Pan CY,Wang YP
Thu Dec 01 00:00:00 EST 2022
Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway.
Frontiers in pharmacology
Xu Z,Zhang M,Wang Y,Chen R,Xu S,Sun X,Yang Y,Lin Z,Wang S,Huang H
Sat Jul 16 00:00:00 EDT 2022
Trans-anethole ameliorates lipopolysaccharide-induced acute liver inflammation in broilers via inhibiting NF-κB signaling pathway.
Poultry science
Tong Y,Yu C,Xie Z,Zhang X,Yang Z,Wang T
Mon Aug 01 00:00:00 EDT 2022
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Pharmacological research
Cai J,Liang J,Zhang Y,Shen L,Lin H,Hu T,Zhan S,Xie M,Liang S,Xian M,Wang S
Wed Jun 01 00:00:00 EDT 2022
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Applied biochemistry and biotechnology
Jiang T,Shen S,Wang L,Zhao M,Li Y,Huang S
Thu Sep 01 00:00:00 EDT 2022
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl4 -induced hepatic fibrosis in mice.
Journal of food biochemistry
Feng XW,Cheng QL,Fang L,Liu WY,Liu LW,Sun CQ,Lu ZH,Li GM,Gu RZ
Mon Aug 01 00:00:00 EDT 2022
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Frontiers in bioengineering and biotechnology
Ding Q,Liu W,Liu X,Ding C,Zhao Y,Dong L,Chen H,Sun S,Zhang Y,Zhang J,Wu M
Sat Jul 16 00:00:00 EDT 2022
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Breast cancer research and treatment
Li C,Li R,Hu X,Zhou G,Jiang G
Fri Apr 01 00:00:00 EDT 2022
Trichostatin A inhibits dendritic cell maturation through down-regulating NF-κ B (p65) pathway.
Molecular biology reports
Yu Y,Liu B,Chen S,Wang J,Chen F,Liu T,Jiang N,Chen W,Weng S,Cai X,Xiang D
Fri Apr 01 00:00:00 EDT 2022
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
The Journal of biological chemistry
Wang X,Yang Y,Zhao D,Zhang S,Chen Y,Chen Y,Feng K,Li X,Han J,Iwakiri Y,Duan Y,Yang X
Tue Feb 01 00:00:00 EST 2022
Aerobic exercise training alleviates renal injury in db/db mice through inhibiting Nox4-mediated NLRP3 inflammasome activation.
Experimental gerontology
Zhou Z,Ying C,Zhou X,Shi Y,Xu J,Zhu Y,Wang M,Li Y,Li X,Xiang J
Sat Oct 15 00:00:00 EDT 2022
Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.
The Journal of nutritional biochemistry
Qi L,Jiang J,Yu G,Zhang X,Qi X,Zhang J,Zhang L,Wang T
Wed Jun 01 00:00:00 EDT 2022
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Journal of neuroinflammation
Dong Y,Yu H,Li X,Bian K,Zheng Y,Dai M,Feng X,Sun Y,He Y,Yu B,Zhang H,Wu J,Yu X,Wu H,Kong W
Mon Aug 15 00:00:00 EDT 2022
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhao AN,Yang Z,Wang DD,Shi B,Zhang H,Bai Y,Yan BW,Zhang Y,Wen JK,Wang XL,Qu CB
Tue Nov 01 00:00:00 EDT 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 EDT 2022
Lentinan inhibits oxidative stress and alleviates LPS-induced inflammation and apoptosis of BMECs by activating the Nrf2 signaling pathway.
International journal of biological macromolecules
Meng M,Huo R,Wang Y,Ma N,Shi X,Shen X,Chang G
Thu Dec 01 00:00:00 EST 2022
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
Viruses
Zhao N,Wang F,Kong Z,Shang Y
Sat Jul 02 00:00:00 EDT 2022
Protective Effects of Three Flavonoids from Dendrobium huoshanense Flowers on Alcohol-Induced Hepatocyte Injury via Activating Nrf2 and Inhibiting NF-κB Pathways.
Chemistry & biodiversity
Li QM,Yang XR,Zha XQ,Pan LH,Zang DD,Zhang FY,Luo JP
Mon Aug 01 00:00:00 EDT 2022
Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice.
Phytotherapy research : PTR
Yan K,Hu J,Hou T,Ci X,Peng L
Sun May 01 00:00:00 EDT 2022
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
Phytotherapy research : PTR
Han X,Zhang J,Zhou L,Wei J,Tu Y,Shi Q,Zhang Y,Ren J,Wang Y,Ying H,Liang G
Wed Jun 01 00:00:00 EDT 2022
Discovery of novel MIF inhibitors that attenuate microglial inflammatory activation by structures-based virtual screening and in vitro bioassays.
Acta pharmacologica Sinica
Zhang Y,Xu L,Zhang Y,Pan J,Wang PQ,Tian S,Li HT,Gao BW,Hou TJ,Zhen XC,Zheng LT
Wed Jun 01 00:00:00 EDT 2022
2-Fluorofucose Attenuates Hydrogen Peroxide-Induced Oxidative Stress in HepG2 Cells via Nrf2/keap1 and NF-κB Signaling Pathways.
Life (Basel, Switzerland)
Tu M,Fan X,Shi J,Jing S,Xu X,Wang Y
Fri Mar 11 00:00:00 EST 2022
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Journal of veterinary research
Deng CY,Zhu TT,Lian S,Wang JF,Wu R,Zheng JS
Tue Mar 01 00:00:00 EST 2022
Nrf2 Activation and NF-Kb & caspase/bax signaling inhibition by sodium butyrate alleviates LPS-induced cell injury in bovine mammary epithelial cells.
Molecular immunology
Ali I,Li C,Kuang M,Shah AU,Shafiq M,Ahmad MA,Abdalmegeed D,Li L,Wang G
Mon Aug 01 00:00:00 EDT 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 EDT 2022
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Frontiers in pharmacology
Li L,Deng S,Liu M,Yang M,Li J,Liu T,Zhang T,Zhao Y,He M,Wu D,Xu Y
Fri Dec 02 00:00:00 EST 2022
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Frontiers in pharmacology
Lin X,Wei Y,Li Y,Xiong Y,Fang B,Li C,Huang Q,Huang R,Wei J
Sat Apr 02 00:00:00 EDT 2022
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Molecular biology reports
Yu K,Tan Z,Xin Y
Fri Apr 01 00:00:00 EDT 2022
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway.
Injury
Zhang Y,Zhu Q,Fang Q,Yin D,Duan Y,Xue G,Ma N,Cai Y,He M
Wed Jun 01 00:00:00 EDT 2022
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Journal of food biochemistry
Mehmood A,Althobaiti F,Zhao L,Usman M,Chen X,Alharthi F,Soliman MM,Shah AA,Murtaza MA,Nadeem M,Ranjha MMAN,Wang C
Sat Oct 01 00:00:00 EDT 2022
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Inflammation
Chen Y,Qu L,Li Y,Chen C,He W,Shen L,Zhang R
Tue Feb 01 00:00:00 EST 2022
Activated AMP-activated protein kinase prevents hepatic steatosis, oxidative stress and inflammation in primary chicken hepatocytes.
Frontiers in physiology
Yao Y,Li L,Wang H,Yang Y,Ma H
Wed Sep 28 00:00:00 EDT 2022
Non-mitogenic fibroblast growth factor 1 protects against ischemic stroke by regulating microglia/macrophage polarization through Nrf2 and NF-κB pathways.
Neuropharmacology
Dordoe C,Wang X,Lin P,Wang Z,Hu J,Wang D,Fang Y,Liang F,Ye S,Chen J,Zhao Y,Xiong Y,Yang Y,Lin L,Li X
Fri Jul 01 00:00:00 EDT 2022
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Molecules (Basel, Switzerland)
Peng J,Cai Z,Wang Q,Zhou J,Xu J,Pan D,Chen T,Zhang G,Tao L,Chen Y,Shen X
Sat Jun 04 00:00:00 EDT 2022
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Journal of experimental & clinical cancer research : CR
Yang W,Li J,Zhang M,Yu H,Zhuang Y,Zhao L,Ren L,Gong J,Bi H,Zeng L,Xue Y,Yang J,Zhao Y,Wang S,Gao S,Fu Z,Li D,Zhang J,Wang T,Shan M,Tang B,Li X
Fri Feb 18 00:00:00 EST 2022
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Journal of experimental & clinical cancer research : CR
Yang W,Li J,Zhang M,Yu H,Zhuang Y,Zhao L,Ren L,Gong J,Bi H,Zeng L,Xue Y,Yang J,Zhao Y,Wang S,Gao S,Fu Z,Li D,Zhang J,Wang T,Shan M,Tang B,Li X
Fri Feb 18 00:00:00 EST 2022
Transcriptional Regulation of RIP2 Gene by NFIB Is Associated with Cellular Immune and Inflammatory Response to APEC Infection.
International journal of molecular sciences
Sun H,Li N,Tan J,Li H,Zhang J,Qu L,Lamont SJ
Wed Mar 30 00:00:00 EDT 2022
A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment.
Stem cell research & therapy
Wang C,Yang Q,Han Y,Liu H,Wang Y,Huang Y,Zheng Y,Li W
Fri Jun 03 00:00:00 EDT 2022
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Bioorganic chemistry
Gong X,He Y,Yang D,Yang S,Li J,Zhao H,Chen Q,Ren Q,Zhang B
Sat Oct 01 00:00:00 EDT 2022
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Experimental gerontology
Chen H,Dong L,Chen X,Ding C,Hao M,Peng X,Zhang Y,Zhu H,Liu W
Wed Jun 15 00:00:00 EDT 2022
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Food science and biotechnology
Wang Z,Liang M,Liu B,Yang L
Wed Jun 01 00:00:00 EDT 2022
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Molecular biology reports
Shi X,Hu Y,Jiang Y,Wu J,Zhang C,Zhang J,Wu S,Wu Y,Dong W,Li J
Tue Mar 01 00:00:00 EST 2022
Single Treatment of Vitamin D3 Ameliorates LPS-Induced Acute Lung Injury through Changing Lung Rodentibacter abundance.
Molecular nutrition & food research
Jin A,Zhao Y,Yuan Y,Ma S,Chen J,Yang X,Lu S,Sun Q
Tue Feb 01 00:00:00 EST 2022
LXR agonist inhibits inflammation through regulating MyD88 mRNA alternative splicing.
Frontiers in pharmacology
Li N,Li Y,Han X,Zhang J,Han J,Jiang X,Wang W,Xu Y,Xu Y,Fu Y,Si S
Wed Nov 02 00:00:00 EDT 2022
Blocking protease-activated receptor 4 alleviates liver injury induced by brain death.
Biochemical and biophysical research communications
Fang H,Yuan Z,Zhu Y,Tang H,Pang C,Li J,Shi J,Guo W,Zhang S
Sat Mar 05 00:00:00 EST 2022
Aggregation-Induced Emission Photosensitizer Synergizes Photodynamic Therapy and the Inhibition of the NF-κB Signaling Pathway to Overcome Hypoxia in Breast Cancer.
ACS applied materials & interfaces
Wang J,Wu H,Zhao Q,Zou Y,Ding D,Yin H,Xu H
Wed Jul 06 00:00:00 EDT 2022
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Journal of cellular and molecular medicine
Yu Q,Cheng P,Wu J,Guo C
Mon Feb 01 00:00:00 EST 2021
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Journal of cellular and molecular medicine
Yu Q,Cheng P,Wu J,Guo C
Mon Feb 01 00:00:00 EST 2021
Resveratrol sustains intestinal barrier integrity, improves antioxidant capacity, and alleviates inflammation in the jejunum of ducks exposed to acute heat stress.
Poultry science
Yang C,Luo P,Chen SJ,Deng ZC,Fu XL,Xu DN,Tian YB,Huang YM,Liu WJ
Mon Nov 01 00:00:00 EDT 2021
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Journal of cellular and molecular medicine
Ma L,Li C,Lian S,Xu B,Lv H,Liu Y,Lu J,Ji H,Li S,Guo J,Yang H
Sun Aug 01 00:00:00 EDT 2021
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Journal of neuroinflammation
Gao C,Jia W,Xu W,Wu Q,Wu J
Sat May 22 00:00:00 EDT 2021
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Food & function
Bai X,Fu R,Duan Z,Liu Y,Zhu C,Fan D
Wed Apr 07 00:00:00 EDT 2021
Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats.
Journal of agricultural and food chemistry
Yuan Y,Lu L,Bo N,Chaoyue Y,Haiyang Y
Wed Nov 03 00:00:00 EDT 2021
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Phytochemistry
Song Z,Gao C,Jiang Q,Xu J,Xiong L,Liu K,Sun D,Li H,Chen L
Wed Dec 01 00:00:00 EST 2021
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Cell death & disease
Zhou W,Zhong Z,Lin D,Liu Z,Zhang Q,Xia H,Peng S,Liu A,Lu Z,Wang Y,Ye S,Ye Q
Wed Feb 24 00:00:00 EST 2021
Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
Molecular medicine reports
Yao Y,Luo R,Xiong S,Zhang C,Zhang Y
Sat May 01 00:00:00 EDT 2021
miR-19a-3p downregulates tissue factor and functions as a potential therapeutic target for sepsis-induced disseminated intravascular coagulation.
Biochemical pharmacology
Zhang R,Lu S,Yang X,Li M,Jia H,Liao J,Jing Q,Wu Y,Wang H,Xiao F,Bai X,Na X,Kang Y,Wan L,Yang J
Fri Oct 01 00:00:00 EDT 2021
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Journal of neurochemistry
Li KY,Xiang XJ,Song L,Chen J,Luo B,Wen QX,Zhong BR,Zhou GF,Deng XJ,Ma YL,Hu LT,Chen GJ
Sat May 01 00:00:00 EDT 2021
IKKβ-NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice.
Science signaling
Catheline SE,Bell RD,Oluoch LS,James MN,Escalera-Rivera K,Maynard RD,Chang ME,Dean C,Botto E,Ketz JP,Boyce BF,Zuscik MJ,Jonason JH
Tue Sep 21 00:00:00 EDT 2021
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy.
Oxidative medicine and cellular longevity
Yang K,Zeng L,Ge A,Yi Y,Wang S,Ge J
Wed May 19 00:00:00 EDT 2021
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy.
Oxidative medicine and cellular longevity
Yang K,Zeng L,Ge A,Yi Y,Wang S,Ge J
Wed May 19 00:00:00 EDT 2021
The Critical Role of NLRP6 Inflammasome in Streptococcus pneumoniae Infection In Vitro and In Vivo.
International journal of molecular sciences
Xu D,Wu X,Peng L,Chen T,Huang Q,Wang Y,Ye C,Peng Y,Hu D,Fang R
Thu Apr 08 00:00:00 EDT 2021
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Cao YY,Wang ZH,Xu QC,Chen Q,Wang Z,Lu WH
Thu Jul 01 00:00:00 EDT 2021
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway.
International immunopharmacology
Zhu Y,Sun D,Liu H,Sun L,Jie J,Luo J,Peng L,Song L
Wed Dec 01 00:00:00 EST 2021
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
Experimental and therapeutic medicine
Hu H,Li C,Zhang H,Wu G,Huang Y
Sat May 01 00:00:00 EDT 2021
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
Cancer biology & medicine
Zhang Z,Ye C,Liu J,Xu W,Wu C,Yu Q,Xu X,Zeng X,Jin H,Wu Y,Yan H
Tue Sep 28 00:00:00 EDT 2021
Baicalin alleviates Mycoplasma gallisepticum-induced oxidative stress and inflammation via modulating NLRP3 inflammasome-autophagy pathway.
International immunopharmacology
Ishfaq M,Wu Z,Wang J,Li R,Chen C,Li J
Wed Dec 01 00:00:00 EST 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
Wed Aug 11 00:00:00 EDT 2021
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
Frontiers in nutrition
Rong Z,Huang Y,Cai H,Chen M,Wang H,Liu G,Zhang Z,Wu J
Fri Oct 01 00:00:00 EDT 2021
Allicin alleviated acrylamide-induced NLRP3 inflammasome activation via oxidative stress and endoplasmic reticulum stress in Kupffer cells and SD rats liver.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Nan B,Yang C,Li L,Ye H,Yan H,Wang M,Yuan Y
Mon Feb 01 00:00:00 EST 2021
Orf Virus ORF120 Protein Positively Regulates the NF-κB Pathway by Interacting with G3BP1.
Journal of virology
Zhou Y,Guan J,Gao F,Li Z,Lan Y,Lu H,Song D,Lv L,Lv P,Xu M,Wang Z,He H,Zhao K,He W
Thu Sep 09 00:00:00 EDT 2021
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Peng X,Hao M,Zhao Y,Cai Y,Chen X,Chen H,Zhang Y,Dong L,Liu X,Ding C,Liu W,Yang M,Luo Y
Wed Dec 01 00:00:00 EST 2021
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Cell biochemistry and function
Lin X,Li Y,Zhang X,Wei Y,Wen S,Lu Z,Huang Q,Wei J
Fri Jan 01 00:00:00 EST 2021
A novel indazole derivative, compound Cyy-272, attenuates LPS-induced acute lung injury by inhibiting JNK phosphorylation.
Toxicology and applied pharmacology
Liu Q,Yan H,Zheng X,Fu L,Bao Y,Zheng H,Liu Z,Zhang X,Chen G
Fri Oct 01 00:00:00 EDT 2021
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Virologica Sinica
Zhuo Y,Guo Z,Ba T,Zhang C,He L,Zeng C,Dai H
Thu Apr 01 00:00:00 EDT 2021
Triptolide reduces salivary gland damage in a non-obese diabetic mice model of Sjögren's syndrome via JAK/STAT and NF-κB signaling pathways.
Journal of clinical biochemistry and nutrition
Guo Y,Ji W,Lu Y,Wang Y
Mon Mar 01 00:00:00 EST 2021
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Frontiers in immunology
Ren J,Yan D,Wang Y,Zhang J,Li M,Xiong W,Jing X,Li P,Zhao W,Xiong X,Wu M,Zhong G
Thu Feb 17 00:00:00 EST 2022
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Molecular vision
Jun L,Lin-Lin S,Hui S
Fri Dec 31 00:00:00 EST 2021
Sub-chronic exposure to realgar induces liver injury via upregulating the TXNIP/NLRP3 pathway and disturbing bile acid homeostasis in mice.
Journal of ethnopharmacology
Li A,Wu X,Yang J,Li J,Guo H,Zhang Y,Jiang H,Huo T
Sun Dec 05 00:00:00 EST 2021
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Science advances
Lei Y,Guerra Martinez C,Torres-Odio S,Bell SL,Birdwell CE,Bryant JD,Tong CW,Watson RO,West LC,West AP
Sat May 01 00:00:00 EDT 2021
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Nucleic acids research
Zong X,Xiao X,Shen B,Jiang Q,Wang H,Lu Z,Wang F,Jin M,Min J,Wang F,Wang Y
Fri Jun 04 00:00:00 EDT 2021
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Qian J,Wang X,Weng W,Zhou G,Zhu S,Liu C
Fri Oct 01 00:00:00 EDT 2021
Rosiglitazone alleviates lipopolysaccharide-induced inflammation in RAW264.7 cells via inhibition of NF-κB and in a PPARγ-dependent manner.
Experimental and therapeutic medicine
Zhou JP,Yang XN,Song Y,Zhou F,Liu JJ,Hu YQ,Chen LG
Thu Jul 01 00:00:00 EDT 2021
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Frontiers in pharmacology
Li T,Jiang G,Hu X,Yang D,Tan T,Gao Z,Chen Z,Xiang C,Li S,Ouyang Z,Guo X
Tue Dec 07 00:00:00 EST 2021
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Journal of medicinal chemistry
Zhou Z,Li Y,Ma X,Cao B,Peng T,Sheng Y,Peng H,Li R,Cao Y,Xi R,Li F,Wang M,Sun H,Zhang G,Zhang H,Hu K,Xiao W,Wang F
Thu Jun 10 00:00:00 EDT 2021
Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p.
Scientific reports
Bai Y,Liu X,Chen Q,Chen T,Jiang N,Guo Z
Mon Oct 04 00:00:00 EDT 2021
LuHui Derivative, A Novel Compound That Inhibits the Fat Mass and Obesity-Associated (FTO), Alleviates the Inflammatory Response and Injury in Hyperlipidemia-Induced Cardiomyopathy.
Frontiers in cell and developmental biology
Yu Y,Pan Y,Fan Z,Xu S,Gao Z,Ren Z,Yu J,Li W,Liu F,Gu J,Yuan Y,Du Z
Sat Dec 11 00:00:00 EST 2021
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Frontiers in medicine
Gu L,Ren F,Fang X,Yuan L,Liu G,Wang S
Tue Jul 13 00:00:00 EDT 2021
The Combination of Schisandrol B and Wedelolactone Synergistically Reverses Hepatic Fibrosis Via Modulating Multiple Signaling Pathways in Mice.
Frontiers in pharmacology
Ai Y,Shi W,Zuo X,Sun X,Chen Y,Wang Z,Li R,Song X,Dai W,Mu W,Ding K,Li Z,Li Q,Xiao X,Zhan X,Bai Z
Mon Oct 25 00:00:00 EDT 2021
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.
Journal of ethnopharmacology
Yao H,Zhao J,Zhu L,Xie Y,Zhao N,Yao R,Sun H,Han G
Mon Nov 15 00:00:00 EST 2021
Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection.
Veterinary research
Zhao J,Wan S,Sun N,Sun P,Sun Y,Khan A,Guo J,Zheng X,Fan K,Yin W,Li H
Wed Jun 23 00:00:00 EDT 2021
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
European journal of pharmacology
Huang X,Pei W,Ni B,Zhang R,You H
Sun Sep 05 00:00:00 EDT 2021
MicroLet-7b Regulates Neutrophil Function and Dampens Neutrophilic Inflammation by Suppressing the Canonical TLR4/NF-κB Pathway.
Frontiers in immunology
Chen B,Han J,Chen S,Xie R,Yang J,Zhou T,Zhang Q,Xia R
Tue May 04 00:00:00 EDT 2021
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
International immunopharmacology
Hu S,Li Y,Wang B,Peng K
Fri Oct 01 00:00:00 EDT 2021
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Foods (Basel, Switzerland)
Zhang J,Ma X,Fan D
Wed May 26 00:00:00 EDT 2021
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Foods (Basel, Switzerland)
Zhang J,Ma X,Fan D
Wed May 26 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Journal of natural products
Gao X,Shen X,Zheng Y,Yang L,Zhang X,Hu G,Jia J,Wang A
Fri Nov 26 00:00:00 EST 2021
Bergenin alleviates H2 O2 -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Environmental toxicology
Zhang G,Wang H,Zhang Q,Zhao Z,Zhu W,Zuo X
Wed Dec 01 00:00:00 EST 2021
Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats.
Frontiers in pharmacology
Zhou L,Zheng LF,Zhang XL,Wang ZY,Yao YS,Xiu XL,Liu CZ,Zhang Y,Feng XY,Zhu JX
Sat Dec 11 00:00:00 EST 2021
Seco-type β-Apocarotenoid Generated by β-Carotene Oxidation Exerts Anti-inflammatory Effects against Activated Macrophages.
Journal of oleo science
Takatani N,Beppu F,Yamano Y,Maoka T,Hosokawa M
Fri Apr 02 00:00:00 EDT 2021
Cigarette smoking induces aberrant N6-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Cancer letters
Jin M,Li G,Liu W,Wu X,Zhu J,Zhao D,Zeng Z,Xiong M,Song Y,He X,Zhang Q,Hu K
Sun Oct 10 00:00:00 EDT 2021
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Cai C,Hu W,Zhang Y,Hu X,Yang S,Qiu H,Wang R,Ma M,Qiu Y,Chu T
Tue Nov 23 00:00:00 EST 2021
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Pulmonary pharmacology & therapeutics
Luo Y,Chen H,Huang R,Wu Q,Li Y,He Y
Sun Aug 01 00:00:00 EDT 2021
Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-κB/MAPK signaling pathways.
International immunopharmacology
Pan J,Chen S,Guo W,Cao S,Shi X,Zhang J,Zhang H,Zhang S
Tue Jun 01 00:00:00 EDT 2021
Dehydroepiandrosterone attenuates LPS-induced inflammatory responses via activation of Nrf2 in RAW264.7 macrophages.
Molecular immunology
Cao J,Li Q,Shen X,Yao Y,Li L,Ma H
Mon Mar 01 00:00:00 EST 2021
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Life sciences
Liu L,Yan LN,Sui Z
Fri Jan 15 00:00:00 EST 2021
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
International journal of pharmaceutics
Yuan SJ,Wang C,Xu HZ,Liu Y,Zheng MY,Li K,Sun SK,Komatsu N,Zhao L,Chen X
Sun Sep 05 00:00:00 EDT 2021
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
International journal of pharmaceutics
Yuan SJ,Wang C,Xu HZ,Liu Y,Zheng MY,Li K,Sun SK,Komatsu N,Zhao L,Chen X
Sun Sep 05 00:00:00 EDT 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 EDT 2021
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.
Neurochemical research
Ren Y,Jiang J,Jiang W,Zhou X,Lu W,Wang J,Luo Y
Wed Sep 01 00:00:00 EDT 2021
A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating β-TrCP E3 Ubiquitin Ligase.
International journal of molecular sciences
Peng T,Wonganan O,Zhang Z,Yu J,Xi R,Cao Y,Suksamrarn A,Zhang G,Wang F
Thu Mar 25 00:00:00 EDT 2021
Inhibitory activity of narirutin on RBL-2H3 cells degranulation.
Immunopharmacology and immunotoxicology
Niu L,Wei J,Li X,Jin Y,Shi X
Mon Feb 01 00:00:00 EST 2021
Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.
Die Pharmazie
Zhuang J,Zhou X,Liu T,Zhang S,Yuan F,Zhang L,Yang Z,Chen Y
Mon Nov 01 00:00:00 EDT 2021
Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation.
Frontiers in immunology
Kong F,Ye S,Zhong Z,Zhou X,Zhou W,Liu Z,Lan J,Xiong Y,Ye Q
Wed Feb 23 00:00:00 EST 2022
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Toxicology
Yuan Y,Wang Z,Nan B,Yang C,Wang M,Ye H,Xi C,Zhang Y,Yan H
Wed Sep 01 00:00:00 EDT 2021
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Journal of experimental & clinical cancer research : CR
Zhang M,Wang L,Yue Y,Zhang L,Liu T,Jing M,Liang X,Ma M,Xu S,Wang K,Wang X,Fan J
Thu Feb 11 00:00:00 EST 2021
Inhibition of DNM1L and mitochondrial fission attenuates inflammatory response in fibroblast-like synoviocytes of rheumatoid arthritis.
Journal of cellular and molecular medicine
Wang X,Chen Z,Fan X,Li W,Qu J,Dong C,Wang Z,Ji Z,Li Y
Wed Jan 01 00:00:00 EST 2020
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Life sciences
Wu S,Zhao M,Sun Y,Xie M,Le K,Xu M,Huang C
Wed Jan 15 00:00:00 EST 2020
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
The international journal of biochemistry & cell biology
Khusbu FY,Zhou X,Roy M,Chen FZ,Cao Q,Chen HC
Wed Jan 01 00:00:00 EST 2020
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Journal of veterinary science
Jin X,Yuan Y,Zhang C,Zhou Y,Song Y,Wei Z,Zhang G
Fri May 01 00:00:00 EDT 2020
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Drug design, development and therapy
Gao Z,Sui J,Fan R,Qu W,Dong X,Sun D
Mon Mar 29 00:00:00 EDT 2021
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
Molecular medicine reports
He H,Xu C,Zheng L,Wang K,Jin M,Sun Y,Yue Z
Sat Feb 01 00:00:00 EST 2020
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
International immunopharmacology
Wu Y,Wang Z,Fu X,Lin Z,Yu K
Tue Sep 01 00:00:00 EDT 2020
NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina.
Development (Cambridge, England)
Palazzo I,Deistler K,Hoang TV,Blackshaw S,Fischer AJ
Fri May 22 00:00:00 EDT 2020
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
BioMed research international
Gao W,Feng Z,Zhang S,Wu B,Geng X,Fan G,Duan Y,Li K,Liu K,Peng C
Mon Mar 22 00:00:00 EDT 2021
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
International immunopharmacology
Feng Z,Pang L,Chen S,Pang X,Huang Y,Qiao Q,Wang Y,Vonglorkham S,Huang Q,Lin X,Wei J
Sun Nov 01 00:00:00 EDT 2020
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
Cellular & molecular immunology
He X,Yang W,Zeng Z,Wei Y,Gao J,Zhang B,Li L,Liu L,Wan Y,Zeng Q,Gong Z,Liu L,Zhang H,Li Y,Yang S,Hu T,Wu L,Masliah E,Huang S,Cao H
Sun Mar 01 00:00:00 EST 2020
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
The Kaohsiung journal of medical sciences
Yang QY,Yang KP,Li ZZ
Wed Jan 01 00:00:00 EST 2020
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
Frontiers in cellular neuroscience
Tong D,Ma Z,Su P,Wang S,Xu Y,Zhang LM,Wu Z,Liu K,Zhao P
Tue Apr 19 00:00:00 EDT 2022
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Inflammation
Huang X,You Y,Xi Y,Ni B,Chu X,Zhang R,You H
Wed Apr 01 00:00:00 EDT 2020
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
Mediators of inflammation
Chen Y,Feng B,Yuan Y,Hu J,Zhao W,Jiang H,Li W,Fan Z,Du Z
Mon Nov 23 00:00:00 EST 2020
Hepatitis B virus core protein promotes the expression of neuraminidase 1 to facilitate hepatocarcinogenesis.
Laboratory investigation; a journal of technical methods and pathology
Kong F,Li N,Tu T,Tao Y,Bi Y,Yuan D,Zhang N,Yang X,Kong D,You H,Zheng K,Tang R
Tue Dec 01 00:00:00 EST 2020
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Acta pharmacologica Sinica
Almoiliqy M,Wen J,Xu B,Sun YC,Lian MQ,Li YL,Qaed E,Al-Azab M,Chen DP,Shopit A,Wang L,Sun PY,Lin Y
Tue Sep 01 00:00:00 EDT 2020
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Pharmaceutical biology
Zhang X,Feng J,Su S,Huang L
Tue Dec 01 00:00:00 EST 2020
Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Wen J,Shen J,Zhou Y,Zhao X,Dai Z,Jin Y
Sun Mar 01 00:00:00 EST 2020
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Neurotoxicity research
Huang M,Guo M,Wang K,Wu K,Li Y,Tian T,Wang Y,Yan W,Zhou Z,Yang H
Wed Apr 01 00:00:00 EDT 2020
Changes in inflammatory factors in SV40MES13 mesangial cells after silencing ApoM gene.
International journal of clinical and experimental pathology
Liu J,Zhang Y,Zhang X,Zhang S,Hu Y,Wang L,Gao J,Zhang Y
Wed Jul 15 00:00:00 EDT 2020
Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway.
Cell & bioscience
Liu L,Xu Y,Dai H,Tan S,Mao X,Chen Z
Wed Apr 13 00:00:00 EDT 2022
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Canadian journal of physiology and pharmacology
Wang T,Zhu H,Hou Y,Duan W,Meng F,Liu Y
Sun Mar 01 00:00:00 EST 2020
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Theranostics
Bao W,Sun C,Sun X,He M,Yu H,Yan W,Wen F,Zhang L,Yang C
Tue Jun 01 00:00:00 EDT 2021
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Journal of cardiovascular pharmacology
Yu J,Sun G,Chen Y,Li L,Wang H,Tu D,Li L,Meng Z,Wang Y
Tue Sep 01 00:00:00 EDT 2020
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Frontiers in pharmacology
Zhang S,Feng Z,Gao W,Duan Y,Fan G,Geng X,Wu B,Li K,Liu K,Peng C
Tue Oct 06 00:00:00 EDT 2020
Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways.
Planta medica
Zeng Q,Zeng Y,Nie X,Guo Y,Zhan Y
Tue Dec 01 00:00:00 EST 2020
Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis.
Frontiers in cell and developmental biology
Lv JJ,Wang H,Cui HY,Liu ZK,Zhang RY,Lu M,Li C,Yong YL,Liu M,Zhang H,Zhang TJ,Zhang K,Li G,Nan G,Zhang C,Guo SP,Wang L,Chen ZN,Bian H
Tue Jan 26 00:00:00 EST 2021
Activation of NF-κB-Inducing Kinase in Islet β Cells Causes β Cell Failure and Diabetes.
Molecular therapy : the journal of the American Society of Gene Therapy
Li X,Wu Y,Song Y,Ding N,Lu M,Jia L,Zhao Y,Liu M,Chen Z
Wed Nov 04 00:00:00 EST 2020
Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice.
Canadian journal of physiology and pharmacology
Liu Y,Zhao J,Lu M,Wang H,Tang F
Wed Jan 01 00:00:00 EST 2020
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Cell calcium
Liu Z,Wang P,Lu S,Guo R,Gao W,Tong H,Yin Y,Han X,Liu T,Chen X,Zhu MX,Yang Z
Tue Apr 28 00:00:00 EDT 2020
Emodin protects against intestinal and lung injury induced by acute intestinal injury by modulating SP-A and TLR4/NF-κB pathway.
Bioscience reports
Qian J,Li G,Jin X,Ma C,Cai W,Jiang N,Zheng J
Wed Sep 30 00:00:00 EDT 2020
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-B Pathway.
The American journal of Chinese medicine
Wu J,Yang CL,Sha YK,Wu Y,Liu ZY,Yuan ZH,Sun ZL
Fri Sep 04 00:00:00 EDT 2020
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
Experimental and molecular pathology
Tian C,Gao F,Li X,Li Z
Wed Apr 01 00:00:00 EDT 2020
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Journal of natural products
Yang WJ,Chen XM,Wang SQ,Hu HX,Cheng XP,Xu LT,Ren DM,Wang XN,Zhao BB,Lou HX,Shen T
Fri Apr 24 00:00:00 EDT 2020
Natural Polyketides Isolated from the Endophytic Fungus Phomopsis sp. CAM212 with a Semisynthetic Derivative Downregulating the ERK/IκBα Signaling Pathways.
Planta medica
Jouda JB,Njoya EM,Fobofou SAT,Zhou ZY,Qiang Z,Mbazoa CD,Brandt W,Zhang GL,Wandji J,Wang F
Tue Sep 01 00:00:00 EDT 2020
Silencing of lncRNA MIAT alleviates LPS-induced pneumonia via regulating miR-147a/NKAP/NF-κB axis.
Aging
Liu M,Li W,Song F,Zhang L,Sun X
Wed Dec 09 00:00:00 EST 2020
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Brain research
Xu B,Lang LM,Lian S,Guo JR,Wang JF,Liu J,Yang HM,Li SZ
Wed Jan 01 00:00:00 EST 2020
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.
Molecular and cellular biochemistry
Yu J,Shen L,Liu Y,Ming H,Zhu X,Chu M,Lin J
Wed Jan 01 00:00:00 EST 2020
Up-regulated DERL3 in fibroblast-like synoviocytes exacerbates inflammation of rheumatoid arthritis.
Clinical immunology (Orlando, Fla.)
Geng M,Xu K,Meng L,Xu J,Jiang C,Guo Y,Ren X,Li X,Peng Y,Wang S,Huang F,Zhang J,Wang X,Zhu W,Lu S
Sun Nov 01 00:00:00 EDT 2020
Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-κB Signaling Pathway.
BioMed research international
Zhang W,Zhou P,Jiang X,Fan Z,Xu X,Wang F
Wed Apr 28 00:00:00 EDT 2021
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Applied microbiology and biotechnology
Din SRU,Zhong M,Nisar MA,Saleem MZ,Hussain A,Khinsar KH,Alam S,Ayub G,Kanwal S,Li X,Zhang W,Wang X,Ning A,Cao J,Huang M
Tue Dec 01 00:00:00 EST 2020
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Food & function
Gu M,Jin J,Ren C,Chen X,Gao W,Wang X,Wu Y,Tian N,Pan Z,Wu A,Zhou Y,Zhang X
Tue Dec 01 00:00:00 EST 2020
5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
International immunopharmacology
Wang M,Zong HF,Chang KW,Han H,Yasir Rizvi M,Iffat Neha S,Li ZY,Yang WN,Qian YH
Tue Mar 03 00:00:00 EST 2020
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation.
International immunopharmacology
Su J,Pan YW,Wang SQ,Li XZ,Huang F,Ma SP
Sun Mar 01 00:00:00 EST 2020
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Journal of agricultural and food chemistry
Li L,Chu X,Yao Y,Cao J,Li Q,Ma H
Wed Oct 07 00:00:00 EDT 2020
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Frontiers in microbiology
Zhang K,Hussain T,Wang J,Li M,Wang W,Ma X,Liao Y,Yao J,Song Y,Liang Z,Zhou X,Xu L
Mon Sep 28 00:00:00 EDT 2020
Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose.
Journal of agricultural and food chemistry
Wang Y,Cui X,Lin Q,Cai J,Tang L,Liang Y
Wed Nov 04 00:00:00 EST 2020
LncRNA NKILA integrates RXFP1/AKT and NF-κB signalling to regulate osteogenesis of mesenchymal stem cells.
Journal of cellular and molecular medicine
Zhang Y,Cao X,Li P,Fan Y,Zhang L,Ma X,Sun R,Liu Y,Li W
Wed Jan 01 00:00:00 EST 2020
Integrated analysis identifies low microRNA-215 expression as associated with a poor prognosis of patients with colorectal cancer through the IKβ-α signaling pathway.
Translational cancer research
Wang Z,Jiang X,Li Q,Jin Y,Liu X,Wang F,Mao Y,Hua D
Tue Sep 01 00:00:00 EDT 2020
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Nature cell biology
Wang L,Yu P,Zhou B,Song J,Li Z,Zhang M,Guo G,Wang Y,Chen X,Han L,Hu S
Wed Jan 01 00:00:00 EST 2020
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Food & function
Lin Z,Fu C,Yan Z,Wu Y,Zhan J,Lou Z,Liao X,Pan J
Thu Mar 26 00:00:00 EDT 2020
Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice.
Food & function
Liu N,Zhang GX,Niu YT,Wang Q,Zheng J,Yang JM,Sun T,Niu JG,Yu JQ
Thu Oct 01 00:00:00 EDT 2020
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Frontiers in microbiology
Zhuang C,Liu G,Barkema HW,Zhou M,Xu S,Ur Rahman S,Liu Y,Kastelic JP,Gao J,Han B
Mon Sep 28 00:00:00 EDT 2020
Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma.
Food & function
Hu M,Yang J,Qu L,Deng X,Duan Z,Fu R,Liang L,Fan D
Wed Jan 29 00:00:00 EST 2020
Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells via PI3K/Akt/NF-κB Signaling Pathway.
Frontiers in pharmacology
Li W,Du Q,Li X,Zheng X,Lv F,Xi X,Huang G,Yang J,Liu S
Mon Sep 28 00:00:00 EDT 2020
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Brain, behavior, and immunity
Xu B,Zang SC,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Fri Feb 01 00:00:00 EST 2019
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Brain, behavior, and immunity
Xu B,Zang SC,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Fri Feb 01 00:00:00 EST 2019
Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing.
Proceedings of the National Academy of Sciences of the United States of America
Bianco C,Thompson L,Mohr I
Tue Nov 05 00:00:00 EST 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
Journal of cellular biochemistry
Jin XH,Jia YS,Shi YH,Li QY,Bao SQ,Lu WP,Tong ZS
Fri Feb 01 00:00:00 EST 2019
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
Journal of cellular biochemistry
Jin XH,Jia YS,Shi YH,Li QY,Bao SQ,Lu WP,Tong ZS
Fri Feb 01 00:00:00 EST 2019
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Veterinary research
Sun P,Sun N,Yin W,Sun Y,Fan K,Guo J,Khan A,He Y,Li H
Fri Jul 12 00:00:00 EDT 2019
Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model.
Asian journal of andrology
Song X,Lin NH,Wang YL,Chen B,Wang HX,Hu K
Mon Aug 17 00:00:00 EDT 2020
Knockdown of cathepsin D protects dopaminergic neurons against neuroinflammation-mediated neurotoxicity through inhibition of NF-κB signalling pathway in Parkinson's disease model.
Clinical and experimental pharmacology & physiology
Gan P,Xia Q,Hang G,Zhou Y,Qian X,Wang X,Ding L
Mon Apr 01 00:00:00 EDT 2019
Knockdown of cathepsin D protects dopaminergic neurons against neuroinflammation-mediated neurotoxicity through inhibition of NF-κB signalling pathway in Parkinson's disease model.
Clinical and experimental pharmacology & physiology
Gan P,Xia Q,Hang G,Zhou Y,Qian X,Wang X,Ding L
Mon Apr 01 00:00:00 EDT 2019
Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.
Antioxidants (Basel, Switzerland)
Jiang J,Qi L,Lv Z,Jin S,Wei X,Shi F
Thu Nov 21 00:00:00 EST 2019
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Drug design, development and therapy
Zhao C,Zhou X,Qiu J,Xin D,Li T,Chu X,Yuan H,Wang H,Wang Z,Wang D
Mon Mar 30 00:00:00 EDT 2020
Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.
Mediators of inflammation
Leng B,Zhang Y,Liu X,Zhang Z,Liu Y,Wang H,Lu M
Mon Jul 22 00:00:00 EDT 2019
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
PloS one
Lang Q,Yidong X,Xueguang Z,Sixian W,Wenming X,Tao Z
Tue Feb 25 00:00:00 EST 2020
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Molecular immunology
Zhao J,Cao J,Yu L,Ma H
Tue Oct 01 00:00:00 EDT 2019
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
International journal of molecular sciences
Zhang L,Wang F,Zhang Q,Liang Q,Wang S,Xian M,Wang F
Tue Oct 29 00:00:00 EDT 2019
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Life sciences
Gao S,Xu T,Guo H,Deng Q,Xun C,Liang W,Sheng W
Fri Nov 15 00:00:00 EST 2019
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
Poultry science
He S,Yu Q,He Y,Hu R,Xia S,He J
Sun Dec 01 00:00:00 EST 2019
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Aging
Liang S,Wang ZG,Zhang ZZ,Chen K,Lv ZT,Wang YT,Cheng P,Sun K,Yang Q,Chen AM
Fri Oct 11 00:00:00 EDT 2019
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Aging
Huang X,Ni B,Xi Y,Chu X,Zhang R,You H
Mon Dec 16 00:00:00 EST 2019
Polysaccharides from Nostoc commune Vaucher activate macrophages via NF-κB and AKT/JNK1/2 pathways to suppress colorectal cancer growth in vivo.
Food & function
Guo M,Li Z,Huang Y,Shi M
Wed Jul 17 00:00:00 EDT 2019
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Molecules (Basel, Switzerland)
Shi H,Wang XL,Quan HF,Yan L,Pei XY,Wang R,Peng XD
Mon Jan 21 00:00:00 EST 2019
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
European journal of pharmacology
Huang X,Xi Y,Mao Z,Chu X,Zhang R,Ma X,Ni B,Cheng H,You H
Sun Sep 15 00:00:00 EDT 2019
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.
Journal of hematology & oncology
Hwang WL,Lan HY,Cheng WC,Huang SC,Yang MH
Fri Jan 25 00:00:00 EST 2019
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Molecular cancer research : MCR
Yang J,Zeng Z,Qiao L,Jiang X,Ma J,Wang J,Ye S,Ma Q,Wei J,Wu M,Huang X,Ma D,Gao Q
Tue Oct 01 00:00:00 EDT 2019
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Molecular cancer research : MCR
Yang J,Zeng Z,Qiao L,Jiang X,Ma J,Wang J,Ye S,Ma Q,Wei J,Wu M,Huang X,Ma D,Gao Q
Tue Oct 01 00:00:00 EDT 2019
Protective effect of metformin on a rat model of lipopolysaccharide-induced preeclampsia.
Fundamental & clinical pharmacology
Hu J,Zhang J,Zhu B
Sun Dec 01 00:00:00 EST 2019
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lin Y,Wang S,Yang Z,Gao L,Zhou Z,Yu P,Wu B
Thu Aug 01 00:00:00 EDT 2019
HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Sun X,Huang X,Zhu X,Liu L,Mo S,Wang H,Wei X,Lu S,Bai F,Wang D,Lin X,Lin J
Mon Jul 01 00:00:00 EDT 2019
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Frontiers in physiology
Doudou NR,Kampo S,Liu Y,Ahmmed B,Zeng D,Zheng M,Mohamadou A,Wen QP,Wang S
Wed Sep 30 00:00:00 EDT 2020
Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation.
Theranostics
Huang S,Wang LL,Xue NN,Li C,Guo HH,Ren TK,Zhan Y,Li WB,Zhang J,Chen XG,Han YX,Zhang JL,Jiang JD
Fri Jul 24 00:00:00 EDT 2020
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditions.
Biochemical and biophysical research communications
Ren L,Zhan P,Wang Q,Wang C,Liu Y,Yu Z,Zhang S
Sun Jun 30 00:00:00 EDT 2019
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Frontiers in pharmacology
Tu C,Huang X,Xiao Y,Song M,Ma Y,Yan J,You H,Wu H
Sat Apr 09 00:00:00 EDT 2022
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
International journal of molecular sciences
Wang Z,Liang M,Li H,Cai L,Yang L
Fri Dec 06 00:00:00 EST 2019
Polychlorinated Biphenyl Quinone Promotes Macrophage-Derived Foam Cell Formation.
Chemical research in toxicology
Yang B,Wang Y,Qin Q,Xia X,Liu Z,Song E,Song Y
Mon Dec 16 00:00:00 EST 2019
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Human reproduction (Oxford, England)
Gou Y,Li X,Li P,Zhang H,Xu T,Wang H,Wang B,Ma X,Jiang X,Zhang Z
Mon Apr 01 00:00:00 EDT 2019
L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
Frontiers in molecular neuroscience
Zhou X,Chu X,Xin D,Li T,Bai X,Qiu J,Yuan H,Liu D,Wang D,Wang Z
Thu Oct 01 00:00:00 EDT 2020
Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice.
Frontiers in microbiology
Zhang Y,Xie H,Tang W,Zeng X,Lin Y,Xu L,Xiao L,Xu J,Wu Z,Yuan D
Wed Sep 30 00:00:00 EDT 2020
Cortistatin binds to TNF-α receptors and protects against osteoarthritis.
EBioMedicine
Zhao Y,Li Y,Qu R,Chen X,Wang W,Qiu C,Liu B,Pan X,Liu L,Vasilev K,Hayball J,Dong S,Li W
Fri Mar 01 00:00:00 EST 2019
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
PLoS pathogens
Wei F,Jiang Z,Sun H,Pu J,Sun Y,Wang M,Tong Q,Bi Y,Ma X,Gao GF,Liu J
Tue Oct 01 00:00:00 EDT 2019
Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway.
Biochemical pharmacology
Jiao L,Wang S,Zheng Y,Wang N,Yang B,Wang D,Yang D,Mei W,Zhao Z,Wang Z
Fri Mar 01 00:00:00 EST 2019
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Phytotherapy research : PTR
Song G,Zhang Y,Yu S,Lv W,Guan Z,Sun M,Wang J
Tue Oct 01 00:00:00 EDT 2019
MiR-940 inhibits migration and invasion of tongue squamous cell carcinoma via regulatingCXCR2/NF-κB system-mediated epithelial-mesenchymal transition.
Naunyn-Schmiedeberg's archives of pharmacology
Ma T,Zhao Z,Wang Z,Wang C,Zhang L
Fri Nov 01 00:00:00 EDT 2019
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Toxicology
Wang R,Li D,Ouyang J,Tian X,Zhao Y,Peng X,Li S,Yu G,Yang J
Sat Jun 15 00:00:00 EDT 2019
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
Genes & development
Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I
Sat Dec 01 00:00:00 EST 2018
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
Genes & development
Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I
Sat Dec 01 00:00:00 EST 2018
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Molecular therapy. Nucleic acids
Cen B,Liao W,Wang Z,Gao L,Wei Y,Huang W,He S,Wang W,Liu X,Pan X,Ji A
Fri Jun 01 00:00:00 EDT 2018
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Molecular therapy. Nucleic acids
Cen B,Liao W,Wang Z,Gao L,Wei Y,Huang W,He S,Wang W,Liu X,Pan X,Ji A
Fri Jun 01 00:00:00 EDT 2018
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Molecular therapy. Nucleic acids
Cen B,Liao W,Wang Z,Gao L,Wei Y,Huang W,He S,Wang W,Liu X,Pan X,Ji A
Fri Jun 01 00:00:00 EDT 2018
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Molecular therapy. Nucleic acids
Cen B,Liao W,Wang Z,Gao L,Wei Y,Huang W,He S,Wang W,Liu X,Pan X,Ji A
Fri Jun 01 00:00:00 EDT 2018
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fan L,Xiao Q,Zhang L,Wang X,Huang Q,Li S,Zhao X,Li Z
Sat Dec 01 00:00:00 EST 2018
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fan L,Xiao Q,Zhang L,Wang X,Huang Q,Li S,Zhao X,Li Z
Sat Dec 01 00:00:00 EST 2018
Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation.
Life sciences
Guo YP,Jiang HK,Jiang H,Tian HY,Li L
Sun Apr 01 00:00:00 EDT 2018
Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation.
Life sciences
Guo YP,Jiang HK,Jiang H,Tian HY,Li L
Sun Apr 01 00:00:00 EDT 2018
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
International immunopharmacology
Zhao X,Yin L,Fang L,Xu L,Sun P,Xu M,Liu K,Peng J
Sat Dec 01 00:00:00 EST 2018
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
International immunopharmacology
Zhao X,Yin L,Fang L,Xu L,Sun P,Xu M,Liu K,Peng J
Sat Dec 01 00:00:00 EST 2018
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
The international journal of biochemistry & cell biology
Ke M,Dong J,Wang Y,Zhang J,Zhang M,Wu Z,Lv Y,Wu R
Wed Aug 01 00:00:00 EDT 2018
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
The international journal of biochemistry & cell biology
Ke M,Dong J,Wang Y,Zhang J,Zhang M,Wu Z,Lv Y,Wu R
Wed Aug 01 00:00:00 EDT 2018
Correlation between the expression of IL‑18 and deep venous thrombosis.
International journal of molecular medicine
Li G,Zhou R,Zhao X,Liu R,Ye C
Wed Aug 01 00:00:00 EDT 2018
Correlation between the expression of IL‑18 and deep venous thrombosis.
International journal of molecular medicine
Li G,Zhou R,Zhao X,Liu R,Ye C
Wed Aug 01 00:00:00 EDT 2018
Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways.
Bioorganic chemistry
Jouda JB,Mfotie Njoya E,Mbazoa CD,Zhou Z,Meli Lannang A,Wandji J,Shiono Y,Wang F
Mon Oct 01 00:00:00 EDT 2018
Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways.
Bioorganic chemistry
Jouda JB,Mfotie Njoya E,Mbazoa CD,Zhou Z,Meli Lannang A,Wandji J,Shiono Y,Wang F
Mon Oct 01 00:00:00 EDT 2018
α7nAChR-mediated recruitment of PP1γ promotes TRAF6/NF-κB cascade to facilitate the progression of Hepatocellular Carcinoma.
Molecular carcinogenesis
Wan C,Wu M,Zhang S,Chen Y,Lu C
Thu Nov 01 00:00:00 EDT 2018
α7nAChR-mediated recruitment of PP1γ promotes TRAF6/NF-κB cascade to facilitate the progression of Hepatocellular Carcinoma.
Molecular carcinogenesis
Wan C,Wu M,Zhang S,Chen Y,Lu C
Thu Nov 01 00:00:00 EDT 2018
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Journal of cellular biochemistry
Ji Y,Cao L,Zeng L,Zhang Z,Xiao Q,Guan P,Chen S,Chen Y,Wang M,Guo D
Thu Feb 01 00:00:00 EST 2018
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Journal of cellular biochemistry
Ji Y,Cao L,Zeng L,Zhang Z,Xiao Q,Guan P,Chen S,Chen Y,Wang M,Guo D
Thu Feb 01 00:00:00 EST 2018
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Experimental gerontology
Wang W,Cai G,Chen X
Sun Jul 01 00:00:00 EDT 2018
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Experimental gerontology
Wang W,Cai G,Chen X
Sun Jul 01 00:00:00 EDT 2018
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Molecular medicine reports
Liu X,Yin S,Chen Y,Wu Y,Zheng W,Dong H,Bai Y,Qin Y,Li J,Feng S,Zhao P
Sun Apr 01 00:00:00 EDT 2018
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Molecular medicine reports
Liu X,Yin S,Chen Y,Wu Y,Zheng W,Dong H,Bai Y,Qin Y,Li J,Feng S,Zhao P
Sun Apr 01 00:00:00 EDT 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
Neuroscience letters
Chen S,Lyu C,Zhou J,Huang S,Zhang Y,Liu G,Liu K,Chen D,Hu Y,Zhou L,Gu Y
Thu Nov 01 00:00:00 EDT 2018
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
Neuroscience letters
Chen S,Lyu C,Zhou J,Huang S,Zhang Y,Liu G,Liu K,Chen D,Hu Y,Zhou L,Gu Y
Thu Nov 01 00:00:00 EDT 2018
Protective effect and mechanism of Lactobacillus on cerebral ischemia reperfusion injury in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Wanchao S,Chen M,Zhiguo S,Futang X,Mengmeng S
Fri Jun 15 00:00:00 EDT 2018
Protective effect and mechanism of Lactobacillus on cerebral ischemia reperfusion injury in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Wanchao S,Chen M,Zhiguo S,Futang X,Mengmeng S
Fri Jun 15 00:00:00 EDT 2018
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Wang C,Luo H,Xu Y,Tao L,Chang C,Shen X
Fri Oct 26 00:00:00 EDT 2018
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Wang C,Luo H,Xu Y,Tao L,Chang C,Shen X
Fri Oct 26 00:00:00 EDT 2018
Geniposide attenuates Aβ25-35-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
RSC advances
Huang XF,Li JJ,Tao YG,Wang XQ,Zhang RL,Zhang JL,Su ZQ,Huang QH,Deng YH
Tue May 22 00:00:00 EDT 2018
N-Methylcytisine Ameliorates Dextran-Sulfate-Sodium-Induced Colitis in Mice by Inhibiting the Inflammatory Response.
Molecules (Basel, Switzerland)
Jiao YF,Lu M,Zhao YP,Liu N,Niu YT,Niu Y,Zhou R,Yu JQ
Sun Feb 25 00:00:00 EST 2018
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Lu X,Wei T,Dong Y,Cai Z,Tang L,Liu M
Thu Jul 12 00:00:00 EDT 2018
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Lu X,Wei T,Dong Y,Cai Z,Tang L,Liu M
Thu Jul 12 00:00:00 EDT 2018
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Shen D,Tian L,Shen T,Sun H,Liu P
Fri Aug 17 00:00:00 EDT 2018
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Shen D,Tian L,Shen T,Sun H,Liu P
Fri Aug 17 00:00:00 EDT 2018
Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Li J,Liu H,Yang Z,Zhou F,Wei T,Dong Y,Xue H,Tang L,Liu M
Sat Feb 03 00:00:00 EST 2018
Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Li J,Liu H,Yang Z,Zhou F,Wei T,Dong Y,Xue H,Tang L,Liu M
Sat Feb 03 00:00:00 EST 2018
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 EDT 2022
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 EDT 2022
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Drug design, development and therapy
Feng J,Chen K,Xia Y,Wu L,Li J,Li S,Wang W,Lu X,Liu T,Guo C
Wed Oct 31 00:00:00 EDT 2018
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Drug design, development and therapy
Feng J,Chen K,Xia Y,Wu L,Li J,Li S,Wang W,Lu X,Liu T,Guo C
Wed Oct 31 00:00:00 EDT 2018
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
Cell death & disease
Guo Y,Min Z,Jiang C,Wang W,Yan J,Xu P,Xu K,Xu J,Sun M,Zhao Y,Hussain S,Zhang R,Wang Q,Han Y,Zhang F,Zhu W,Li D,Meng L,Sun J,Lu S
Wed Jun 13 00:00:00 EDT 2018
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
Cell death & disease
Guo Y,Min Z,Jiang C,Wang W,Yan J,Xu P,Xu K,Xu J,Sun M,Zhao Y,Hussain S,Zhang R,Wang Q,Han Y,Zhang F,Zhu W,Li D,Meng L,Sun J,Lu S
Wed Jun 13 00:00:00 EDT 2018
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
The EMBO journal
Khan MR,Xiang S,Song Z,Wu M
Fri Dec 01 00:00:00 EST 2017
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
The EMBO journal
Khan MR,Xiang S,Song Z,Wu M
Fri Dec 01 00:00:00 EST 2017
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
The EMBO journal
Dalet A,Argüello RJ,Combes A,Spinelli L,Jaeger S,Fallet M,Vu Manh TP,Mendes A,Perego J,Reverendo M,Camosseto V,Dalod M,Weil T,Santos MA,Gatti E,Pierre P
Wed Mar 15 00:00:00 EDT 2017
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
The EMBO journal
Dalet A,Argüello RJ,Combes A,Spinelli L,Jaeger S,Fallet M,Vu Manh TP,Mendes A,Perego J,Reverendo M,Camosseto V,Dalod M,Weil T,Santos MA,Gatti E,Pierre P
Wed Mar 15 00:00:00 EDT 2017
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
Journal of virology
Qian S,Fan W,Liu T,Wu M,Zhang H,Cui X,Zhou Y,Hu J,Wei S,Chen H,Li X,Qian P
Tue Aug 15 00:00:00 EDT 2017
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
Journal of virology
Qian S,Fan W,Liu T,Wu M,Zhang H,Cui X,Zhou Y,Hu J,Wei S,Chen H,Li X,Qian P
Tue Aug 15 00:00:00 EDT 2017
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
European journal of pharmacology
Chen HB,Luo CD,Liang JL,Zhang ZB,Lin GS,Wu JZ,Li CL,Tan LH,Yang XB,Su ZR,Xie JH,Zeng HF
Fri Sep 15 00:00:00 EDT 2017
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
European journal of pharmacology
Chen HB,Luo CD,Liang JL,Zhang ZB,Lin GS,Wu JZ,Li CL,Tan LH,Yang XB,Su ZR,Xie JH,Zeng HF
Fri Sep 15 00:00:00 EDT 2017
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Investigative ophthalmology & visual science
Gu R,Lei B,Jiang C,Xu G
Sun Jan 01 00:00:00 EST 2017
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Investigative ophthalmology & visual science
Gu R,Lei B,Jiang C,Xu G
Sun Jan 01 00:00:00 EST 2017
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
Inflammation
Zhao H,Xia Y,Gan H
Fri Dec 01 00:00:00 EST 2017
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
Inflammation
Zhao H,Xia Y,Gan H
Fri Dec 01 00:00:00 EST 2017
Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner.
Toxicology and applied pharmacology
Xu W,Lu C,Yao L,Zhang F,Shao J,Zheng S
Sun Jan 15 00:00:00 EST 2017
Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner.
Toxicology and applied pharmacology
Xu W,Lu C,Yao L,Zhang F,Shao J,Zheng S
Sun Jan 15 00:00:00 EST 2017
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1G93A ALS Mice.
Neurochemical research
Wang W,Duan W,Wang Y,Wen D,Liu Y,Li Z,Hu H,Cui H,Cui C,Lin H,Li C
Sat Apr 01 00:00:00 EDT 2017
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1G93A ALS Mice.
Neurochemical research
Wang W,Duan W,Wang Y,Wen D,Liu Y,Li Z,Hu H,Cui H,Cui C,Lin H,Li C
Sat Apr 01 00:00:00 EDT 2017
Calcitonin gene-related peptide exerts anti-inflammatory property through regulating murine macrophages polarization in vitro.
Molecular immunology
Duan JX,Zhou Y,Zhou AY,Guan XX,Liu T,Yang HH,Xie H,Chen P
Wed Nov 01 00:00:00 EDT 2017
Calcitonin gene-related peptide exerts anti-inflammatory property through regulating murine macrophages polarization in vitro.
Molecular immunology
Duan JX,Zhou Y,Zhou AY,Guan XX,Liu T,Yang HH,Xie H,Chen P
Wed Nov 01 00:00:00 EDT 2017
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Molecular immunology
Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P
Wed Feb 01 00:00:00 EST 2017
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Molecular immunology
Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P
Wed Feb 01 00:00:00 EST 2017
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
Tue Aug 01 00:00:00 EDT 2017
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
Tue Aug 01 00:00:00 EDT 2017
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Biochemical and biophysical research communications
Tang J,Dong Q
Sun Jan 22 00:00:00 EST 2017
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Biochemical and biophysical research communications
Tang J,Dong Q
Sun Jan 22 00:00:00 EST 2017
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Frontiers in pharmacology
Yao H,Sun Y,Song S,Qi Y,Tao X,Xu L,Yin L,Han X,Xu Y,Li H,Sun H,Peng J
Wed Sep 30 00:00:00 EDT 2020
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Frontiers in pharmacology
Yao H,Sun Y,Song S,Qi Y,Tao X,Xu L,Yin L,Han X,Xu Y,Li H,Sun H,Peng J
Wed Sep 30 00:00:00 EDT 2020
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System.
Frontiers in pharmacology
Peng J,Tang ZH,Ren Z,He B,Zeng Y,Liu LS,Wang Z,Wei DH,Zheng XL,Jiang ZS
Wed Sep 30 00:00:00 EDT 2020
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System.
Frontiers in pharmacology
Peng J,Tang ZH,Ren Z,He B,Zeng Y,Liu LS,Wang Z,Wei DH,Zheng XL,Jiang ZS
Wed Sep 30 00:00:00 EDT 2020
Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor-dependent inhibition of hepatic stellate cell contraction.
The FEBS journal
Xu W,Lu C,Zhang F,Shao J,Yao S,Zheng S
Sun Jan 01 00:00:00 EST 2017
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Inflammation
Tu J,Li W,Zhang Y,Wu X,Song Y,Kang L,Liu W,Wang K,Li S,Hua W,Yang C
Thu Jun 01 00:00:00 EDT 2017
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Oncotarget
Lian S,Guo J,Wang L,Li W,Wang J,Ji H,Kong F,Xu B,Li S,Yang H
Fri Dec 29 00:00:00 EST 2017
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Oncotarget
Lian S,Guo J,Wang L,Li W,Wang J,Ji H,Kong F,Xu B,Li S,Yang H
Fri Dec 29 00:00:00 EST 2017
ApoE Influences the Blood-Brain Barrier Through the NF-κB/MMP-9 Pathway After Traumatic Brain Injury.
Scientific reports
Teng Z,Guo Z,Zhong J,Cheng C,Huang Z,Wu Y,Tang S,Luo C,Peng X,Wu H,Sun X,Jiang L
Thu Jul 27 00:00:00 EDT 2017
ApoE Influences the Blood-Brain Barrier Through the NF-κB/MMP-9 Pathway After Traumatic Brain Injury.
Scientific reports
Teng Z,Guo Z,Zhong J,Cheng C,Huang Z,Wu Y,Tang S,Luo C,Peng X,Wu H,Sun X,Jiang L
Thu Jul 27 00:00:00 EDT 2017
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Genes & cancer
Yang W,Yang S,Zhang M,Gao D,He T,Guo M
Wed Mar 01 00:00:00 EST 2017
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Genes & cancer
Yang W,Yang S,Zhang M,Gao D,He T,Guo M
Wed Mar 01 00:00:00 EST 2017
An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes.
Scientific reports
Huang XT,Li C,Peng XP,Guo J,Yue SJ,Liu W,Zhao FY,Han JZ,Huang YH,Cheng QM,Zhou ZG,Chen C,Feng DD,Luo ZQ
Fri Mar 17 00:00:00 EDT 2017
An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes.
Scientific reports
Huang XT,Li C,Peng XP,Guo J,Yue SJ,Liu W,Zhao FY,Han JZ,Huang YH,Cheng QM,Zhou ZG,Chen C,Feng DD,Luo ZQ
Fri Mar 17 00:00:00 EDT 2017
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Autophagy
Huang Q,Zhan L,Cao H,Li J,Lyu Y,Guo X,Zhang J,Ji L,Ren T,An J,Liu B,Nie Y,Xing J
Thu Jun 02 00:00:00 EDT 2016
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Autophagy
Huang Q,Zhan L,Cao H,Li J,Lyu Y,Guo X,Zhang J,Ji L,Ren T,An J,Liu B,Nie Y,Xing J
Thu Jun 02 00:00:00 EDT 2016
An injectable silk sericin hydrogel promotes cardiac functional recovery after ischemic myocardial infarction.
Acta biomaterialia
Song Y,Zhang C,Zhang J,Sun N,Huang K,Li H,Wang Z,Huang K,Wang L
Thu Sep 01 00:00:00 EDT 2016
An injectable silk sericin hydrogel promotes cardiac functional recovery after ischemic myocardial infarction.
Acta biomaterialia
Song Y,Zhang C,Zhang J,Sun N,Huang K,Li H,Wang Z,Huang K,Wang L
Thu Sep 01 00:00:00 EDT 2016
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
International immunopharmacology
Wang K,Wang Y,Qi Q,Zhang F,Zhang Y,Zhu X,Liu G,Luan Y,Zhao Z,Cai J,Cao J,Li S
Sun May 01 00:00:00 EDT 2016
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
International immunopharmacology
Wang K,Wang Y,Qi Q,Zhang F,Zhang Y,Zhu X,Liu G,Luan Y,Zhao Z,Cai J,Cao J,Li S
Sun May 01 00:00:00 EDT 2016
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Journal of molecular medicine (Berlin, Germany)
Zhai Y,Wu B,Li J,Yao XY,Zhu P,Chen ZN
Fri Jan 01 00:00:00 EST 2016
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Journal of molecular medicine (Berlin, Germany)
Zhai Y,Wu B,Li J,Yao XY,Zhu P,Chen ZN
Fri Jan 01 00:00:00 EST 2016
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Chemico-biological interactions
Wu J,Yang C,Guo C,Li X,Yang N,Zhao L,Hang H,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z
Mon Jan 25 00:00:00 EST 2016
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Chemico-biological interactions
Wu J,Yang C,Guo C,Li X,Yang N,Zhao L,Hang H,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z
Mon Jan 25 00:00:00 EST 2016
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
Molecular medicine reports
Zhang Y,Li RM,Wang C,Liu N,Lv S,Xiong JY
Thu Dec 01 00:00:00 EST 2016
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
Molecular medicine reports
Zhang Y,Li RM,Wang C,Liu N,Lv S,Xiong JY
Thu Dec 01 00:00:00 EST 2016
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
BioMed research international
Liu J,Chen Q,Jian Z,Xiong X,Shao L,Jin T,Zhu X,Wang L
Thu Feb 09 00:00:00 EST 2017
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
BioMed research international
Liu J,Chen Q,Jian Z,Xiong X,Shao L,Jin T,Zhu X,Wang L
Thu Feb 09 00:00:00 EST 2017
Matrine displayed antiviral activity in porcine alveolar macrophages co-infected by porcine reproductive and respiratory syndrome virus and porcine circovirus type 2.
Scientific reports
Sun N,Sun P,Lv H,Sun Y,Guo J,Wang Z,Luo T,Wang S,Li H
Fri Apr 15 00:00:00 EDT 2016
Matrine displayed antiviral activity in porcine alveolar macrophages co-infected by porcine reproductive and respiratory syndrome virus and porcine circovirus type 2.
Scientific reports
Sun N,Sun P,Lv H,Sun Y,Guo J,Wang Z,Luo T,Wang S,Li H
Fri Apr 15 00:00:00 EDT 2016
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Scientific reports
He M,Wang M,Huang Y,Peng W,Zheng Z,Xia N,Xu J,Tian D
Wed Jun 08 00:00:00 EDT 2016
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Scientific reports
He M,Wang M,Huang Y,Peng W,Zheng Z,Xia N,Xu J,Tian D
Wed Jun 08 00:00:00 EDT 2016
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
Scientific reports
Liu Q,Zhang Z,Zheng Z,Zheng C,Liu Y,Hu Q,Ke X,Wang H
Wed Jun 22 00:00:00 EDT 2016
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
Scientific reports
Liu Q,Zhang Z,Zheng Z,Zheng C,Liu Y,Hu Q,Ke X,Wang H
Wed Jun 22 00:00:00 EDT 2016
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
International immunopharmacology
Zhang F,Zhang Y,Wang K,Zhu X,Lin G,Zhao Z,Li S,Cai J,Cao J
Tue Dec 01 00:00:00 EST 2015
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
International immunopharmacology
Zhang F,Zhang Y,Wang K,Zhu X,Lin G,Zhao Z,Li S,Cai J,Cao J
Tue Dec 01 00:00:00 EST 2015
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
International journal of molecular medicine
Shi X,Chen G,Liu X,Qiu Y,Yang S,Zhang Y,Fang X,Zhang C,Liu X
Thu Jan 01 00:00:00 EST 2015
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
International journal of molecular medicine
Shi X,Chen G,Liu X,Qiu Y,Yang S,Zhang Y,Fang X,Zhang C,Liu X
Thu Jan 01 00:00:00 EST 2015
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Molecular cancer
Wang F,Yang JL,Yu KK,Xu M,Xu YZ,Chen L,Lu YM,Fang HS,Wang XY,Hu ZQ,Li FF,Kan L,Luo J,Wang SY
Tue Jan 27 00:00:00 EST 2015
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Molecular cancer
Wang F,Yang JL,Yu KK,Xu M,Xu YZ,Chen L,Lu YM,Fang HS,Wang XY,Hu ZQ,Li FF,Kan L,Luo J,Wang SY
Tue Jan 27 00:00:00 EST 2015
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
International journal of molecular sciences
Mao Y,Zhang S,Yu F,Li H,Guo C,Fan X
Thu Sep 10 00:00:00 EDT 2015
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
International journal of molecular sciences
Mao Y,Zhang S,Yu F,Li H,Guo C,Fan X
Thu Sep 10 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Cellular signalling
Zheng C,Zheng Z,Zhang Z,Meng J,Liu Y,Ke X,Hu Q,Wang H
Tue Dec 01 00:00:00 EST 2015
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Journal of virology
Wang K,Ni L,Wang S,Zheng C
Tue Jul 01 00:00:00 EDT 2014
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Journal of virology
Wang K,Ni L,Wang S,Zheng C
Tue Jul 01 00:00:00 EDT 2014
Chlorogenic acid prevents isoproterenol-induced hypertrophy in neonatal rat myocytes.
Toxicology letters
Li Y,Shen D,Tang X,Li X,Wo D,Yan H,Song R,Feng J,Li P,Zhang J,Li J
Fri May 02 00:00:00 EDT 2014
Chlorogenic acid prevents isoproterenol-induced hypertrophy in neonatal rat myocytes.
Toxicology letters
Li Y,Shen D,Tang X,Li X,Wo D,Yan H,Song R,Feng J,Li P,Zhang J,Li J
Fri May 02 00:00:00 EDT 2014
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
International journal of oncology
Luo J,Zhou H,Wang F,Xia X,Sun Q,Wang R,Cheng B
Wed May 01 00:00:00 EDT 2013
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
International journal of oncology
Luo J,Zhou H,Wang F,Xia X,Sun Q,Wang R,Cheng B
Wed May 01 00:00:00 EDT 2013
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Journal of cancer research and clinical oncology
Zhang L,Tang H,Kou Y,Li R,Zheng Y,Wang Q,Zhou X,Jin L
Mon Jul 01 00:00:00 EDT 2013
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Journal of cancer research and clinical oncology
Zhang L,Tang H,Kou Y,Li R,Zheng Y,Wang Q,Zhou X,Jin L
Mon Jul 01 00:00:00 EDT 2013
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
PloS one
Tang S,Bao H,Zhang Y,Yao J,Yang P,Chen X
Tue Dec 03 00:00:00 EST 2013
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
PloS one
Tang S,Bao H,Zhang Y,Yao J,Yang P,Chen X
Tue Dec 03 00:00:00 EST 2013
