Invitrogen

Influenza A M1 Monoclonal Antibody (GA2B)

Influenza A M1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 1

Influenza A M1 Antibody (MA1-80736) in ICC/IF

Frontiers in immunology 2022 - The AMT㤠 - combination treatment reduces influenza virus uncoating in host cells. (A) MDCK cells were infected with 100 MOI of the indicated influenza A virus strains and incubated at 4degC for 1 h. Unbound virions were washed out, and MDCK cells were exposed to different treatment conditions for 1 h at 37degC, as indicated. Cells were fixed, and the cellular location of the viral M1 matrix protein was dete... View More

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Product Details

MA1-80736

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

Immunocytochemistry (ICC/IF)

1:100

View 1 publication 1 publication

Flow Cytometry (Flow)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Virus

Published species

Virus

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

GA2B

Immunogen

Influenza A / Puerto Rico / 8 / 34 (H1N1) and A/Bangkok / 1 / 79 (H3N2) viruses.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.5

Contains

<0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_934284

Product Specific Information

Purity is >90% IgG content by SDS PAGE.

Mouse anti Influenza A matrix protein 1 antibody, clone GA2B recognizes an epitope within the influenza A matrix protein 1.

Target Information

Influenza A virus matrix 1, M1, is a critical protein required for assembly and budding. Hemagglutinin associates with M1 via its cytoplasmic tail and transmembrane domain. The M2 and nucleoprotein proteins are critical in the replication cycle of influenza viruses. The M2 channel protein is an essential component of the viral envelope because of its ability to form a highly selective, pH-regulated, proton-conducting channel. The M2 channel allows protons to enter the interior of the virus and acidification weakens the interaction of the M1 protein with the ribonuclear core.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Hypothiocyanite and Amantadine Combination Treatment Prevents Lethal Influenza A Virus Infection in Mice.

Frontiers in immunology

Ashtiwi NM,Sarr D,Nagy T,Reneer ZB,Tripp RA,Rada B

Published figure using Influenza A M1 monoclonal antibody (Product # MA1-80736) in Immunocytochemistry

Wed Jun 08 00:00:00 EDT 2022

A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets.

Science advances

van de Ven K,Lanfermeijer J,van Dijken H,Muramatsu H,Vilas Boas de Melo C,Lenz S,Peters F,Beattie MB,Lin PJC,Ferreira JA,van den Brand J,van Baarle D,Pardi N,de Jonge J

MA1-80736 was used in Western Blotting to show that mRNA vaccines encoding internal influenza virus proteins represent a promising strategy to induce broadly protective T cell immunity against influenza viruses.

Wed Dec 14 00:00:00 EST 2022

Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer.

PLoS biology

Selzer L,Su Z,Pintilie GD,Chiu W,Kirkegaard K

MA1-80736 was used in Western Blotting to reveal protein-protein interfaces required for the formation of multilayered helical M1 oligomers similar to those observed in virions exposed to the low pH of cell entry.

Tue Sep 01 00:00:00 EDT 2020

Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread.

Nature communications

Jacobs NT,Onuoha NO,Antia A,Steel J,Antia R,Lowen AC

MA1-80736 was used in Flow Cytometry to quantify influenza A virus incomplete viral genomes (IVGs) and examine their fitness implications using a single-cell approach.

Tue Aug 06 00:00:00 EDT 2019

Global Interactomics Connect Nuclear Mitotic Apparatus Protein NUMA1 to Influenza Virus Maturation.

Viruses

Rahim MN,Klewes L,Zahedi-Amiri A,Mai S,Coombs KM

MA1-80736 was used in Western Blot to study the host proteins and processes required for replication and maturation of influenza A virus.

Wed Dec 19 00:00:00 EST 2018

Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low Temperatures.

Journal of virology

Hayashi T,Wills S,Bussey KA,Takimoto T

MA1-80736 was used in western blot to study avian viral polymerase mutants.

Sat Aug 01 00:00:00 EDT 2015

Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing.

PLoS pathogens

Fournier G,Chiang C,Munier S,Tomoiu A,Demeret C,Vidalain PO,Jacob Y,Naffakh N

MA1-80736 was used in western blot to determine viral mRNA splicing controlled by the recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase

Sun Jun 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: Influenza M1

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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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