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Invitrogen
Influenza A PA (A/WSN/1933) Recombinant Rabbit Monoclonal Antibody (HL1388)
FIGURE: 1 / 3
Influenza A PA (A/WSN/1933) Antibody (MA5-47024) in ICC/IF
Immunofluorescent analysis of Influenza A PA (A/WSN/1933) in mock and transfected 293T cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Influenza A virus PA protein stained by Influenza A virus PA protein monoclonal antibody (Product # MA5-47024) diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
MA5-47024
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1388
Immunogen
Recombinant protein encompassing a sequence within the C-term region of Influenza A virus PA protein (A/WSN/1933(H1N1)). The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938096
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
Influenza viruses consists of three types (Influenza A, B, and C), which make up three of the five genera in the Orthomyxoviridae family. Commonly know as the flu, influenza strains can affect both birds and mammals. Influenza strains form roughly spherical particles and are similar in composition with viral envelope containing two main types of glycoproteins (hemagglutinin and neuraminidase), wrapped around the central core of the viral RNA genome and other viral proteins that package and protect the RNA. Unusually for a virus, the influenzavirus genome is not a single piece of nucleic acid; rather a seven to eight segmented fragments of negative-sense RNA with each fragment expressing different viral proteins. Influenza spreads seasonally, resulting in about three to five million yearly cases of severe illness and about 250,000 to 500,000 deaths annually or into the millions in pandemic years. Influenza A virus contains eight single stranded, negative sense RNAs. Each RNA is associated with viral RNA-dependent RNA polymerase which consists of PA, PB1 and PB2 proteins. Recent reports indicate the involvement of PA in 'cap-snatching' mechanism via its endonuclease activity which is essential for cRNA-dependent viral RNA synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Influenza PA
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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