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NeoBiotechnologies
Integrin alpha V + beta 6 Monoclonal Antibody (AvB6 53a.2)
Product Details
RTM1-2500-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rat
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
AvB6 53a.2
Immunogen
Mouse fibroblasts retrovirally infected with cDNA to human beta6. Cells expressed a mouse/human avb6 chimera.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha v integrin; antigen identified by monoclonal antibody L230; CD51; integrin alpha V; Integrin alpha-V; integrin alphaVbeta3; integrin beta 6; Integrin beta-6; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 6; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); Vitronectin receptor subunit alpha
Gene Aliases: 1110004F14Rik; 2210409C20Rik; 2610028E01Rik; 4831415H04Rik; AI1H; CD51; D430040G12Rik; ITGAV; ITGB6; MSK8; VNRA; VTNR
UniProt ID: (Human) P06756, (Human) P18564, (Mouse) P43406, (Mouse) Q9Z0T9
Entrez Gene ID: (Human) 3685, (Human) 3694, (Mouse) 16410, (Mouse) 16420
virus receptor activity
opsonin binding
fibronectin binding
protease binding
protein kinase C binding
voltage-gated calcium channel activity
protein binding
coreceptor activity
fibroblast growth factor binding
C-X3-C chemokine binding
insulin-like growth factor I binding
neuregulin binding
metal ion binding
transforming growth factor beta binding
extracellular matrix binding
extracellular matrix protein binding
integrin binding
receptor binding
peptide binding
protein heterodimerization activity
receptor activity
integrin
angiogenesis
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
positive regulation of cell proliferation
negative regulation of macrophage derived foam cell differentiation
negative regulation of lipid storage
cell growth
cell migration
extracellular matrix organization
positive regulation of cell migration
cell-substrate adhesion
negative regulation of lipid transport
positive regulation of osteoblast proliferation
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
endodermal cell differentiation
apolipoprotein A-I-mediated signaling pathway
apoptotic cell clearance
negative regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of cell adhesion
viral entry into host cell
vascular endothelial growth factor receptor signaling pathway
negative regulation of lipoprotein metabolic process
regulation of phagocytosis
leukocyte migration
negative chemotaxis
entry of symbiont into host cell by promotion of host phagocytosis
ERK1 and ERK2 cascade
calcium ion transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
regulation of apoptotic cell clearance
negative regulation of entry of bacterium into host cell
negative regulation of extrinsic apoptotic signaling pathway
inflammatory response
blood vessel development
cellular calcium ion homeostasis
positive regulation of cytosolic calcium ion concentration
multicellular organism development
fertilization
cell differentiation
detection of molecule of bacterial origin
regulation of ion transmembrane transport
gonad morphogenesis
T cell activation
positive regulation of MAPK cascade
endothelial cell migration
regulation of bone resorption
focal adhesion assembly
release of sequestered calcium ion into cytosol
trophoblast giant cell differentiation
response to nitric oxide
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