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Invitrogen
JARID2 Monoclonal Antibody (7H1B3)
FIGURE: 1 / 5
JARID2 Antibody (MA5-38546) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of JARID2 in HeLa cells using JARID2 Monoclonal Antibody (Product # MA5-38546) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Product # 35503)
Product Details
MA5-38546
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
7H1B3
Immunogen
Purified recombinant fragment of human JARID2 (aa: 1097-1246) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898458
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Jumonji (JARID2) is a nuclear protein that participates in the negative regulation of cell growth. It is required for neural tube formation and is essential for normal heart development and function. Also, it is a part of a group of proteins characterized by a novel structural motif, the JmjC domain, which is implicated in chromatin regulation through histone demethylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: JARD2 antibody; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji-like protein; Jumonji/ARID domain-containing protein 2; Protein Jumonji
Gene Aliases: JARID2; JMJ
UniProt ID: (Human) Q92833
Entrez Gene ID: (Human) 3720
negative regulation of transcription from RNA polymerase II promoter
liver development
transcription, DNA-templated
central nervous system development
negative regulation of cell proliferation
covalent chromatin modification
negative regulation of histone methylation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
spleen development
thymus development
stem cell differentiation
positive regulation of histone H3-K9 methylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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