Product References
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Chinese journal of natural medicines
Teng L,Shen Y,Qu Y,Yang L,Yang Y,Jian X,Fan S,Zhang L,Fu Q
Wed Feb 01 00:00:00 EST 2023
Oral-specific microenvironments regulate cell behavior and anticancer drug sensitivity of tongue squamous cell carcinoma.
Human cell
Iwamoto S,Nishiyama M,Kawasaki M,Morito S,Sakumoto T,Toda S,Yamashita Y,Aoki S
Wed Mar 01 00:00:00 EST 2023
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway.
Heliyon
Meng D,Deng X,Wu Y,Wu J,Zhang Y,Zhang J,Zhao Y,Che Y
Thu Jun 01 00:00:00 EDT 2023
Naringenin Attenuates Isoprenaline-Induced Cardiac Hypertrophy by Suppressing Oxidative Stress through the AMPK/NOX2/MAPK Signaling Pathway.
Nutrients
Li Y,He B,Zhang C,He Y,Xia T,Zeng C
Thu Mar 09 00:00:00 EST 2023
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Redox biology
Wang Z,Tan C,Duan C,Wu J,Zhou D,Hou L,Qian W,Han C,Hou X
Sat Apr 01 00:00:00 EDT 2023
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Experimental and therapeutic medicine
Qian X,Xiong S,Chen Q,Zhang J,Xie J
Sat Apr 01 00:00:00 EDT 2023
Deciphering the molecular mechanism of the THBS1 gene in the TNF signaling axis in glioma stem cells.
Cellular signalling
Chen L,Fang W,Chen W,Wei Y,Ding J,Li J,Lin J,Wu Q
Thu Jun 01 00:00:00 EDT 2023
Administration of serotonin and norepinephrine reuptake inhibitors tends to have less ocular surface damage in a chronic stress-induced rat model of depression than selective serotonin reuptake inhibitors.
Experimental eye research
Zhao H,Yin Y,Lin T,Wang W,Gong L
Thu Jun 01 00:00:00 EDT 2023
11β-Hydroxysteroid dehydrogenase type 1 amplifies inflammation in LPS-induced THP-1 cells.
Iranian journal of basic medical sciences
Luo L,Zhu D,Zhang Z,Zeng H,Huang M,Zhou S
Wed Mar 01 00:00:00 EST 2023
Targeting Nrf2 with 3 H-1,2-dithiole-3-thione to moderate OXPHOS-driven oxidative stress attenuates IL-17A-induced psoriasis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu CT,Yen JJ,Brown DA,Song YC,Chu MY,Hung YH,Tang YH,Wu PY,Yen HR
Wed Mar 01 00:00:00 EST 2023
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Huang H,Li X,Zha D,Lin H,Yang L,Wang Y,Xu L,Wang L,Lei T,Zhou Z,Xiao YF,Xin HB,Fu M,Qian Y
Tue Aug 01 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
The Protective Role of Scorias spongiosa Polysaccharide-Based Microcapsules on Intestinal Barrier Integrity in DSS-Induced Colitis in Mice.
Foods (Basel, Switzerland)
Xu Y,Feng H,Zhang Z,Zhang Q,Tang J,Zhou J,Wang Y,Peng W
Fri Feb 03 00:00:00 EST 2023
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Chemico-biological interactions
Li J,Bai J,Si X,Jia H,Wu Z
Sat Apr 01 00:00:00 EDT 2023
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Bioorganic chemistry
Zhang J,Sun Y,Sun C,Shang D
Wed Mar 01 00:00:00 EST 2023
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Endocrinology
Wang L,Li X,Bu T,Wu X,Li L,Gao S,Yun D,Zhang Y,Chen H,Sun F,Cheng CY
Mon Apr 17 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues.
Autoimmunity
Qiu Q,Yu X,Chen Q,He X
Fri Dec 01 00:00:00 EST 2023
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
British journal of pharmacology
Zhang L,Ma X,Shi R,Zhang L,Zhao R,Duan R,Qin Y,Gao S,Li X,Duan J,Li J
Wed Mar 01 00:00:00 EST 2023
Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway.
Frontiers in pharmacology
He J,Yang Y,Zhang F,Li Y,Li X,Pu X,He X,Zhang M,Yang X,Yu Q,Qi Y,Li X,Yu J
Mon Jun 05 00:00:00 EDT 2023
Aerobic exercise promotes the expression of ATGL and attenuates inflammation to improve hepatic steatosis via lncRNA SRA.
Scientific reports
Wu B,Xu C,Tian Y,Zeng Y,Yan F,Chen A,Zhao J,Chen L
Wed Mar 30 00:00:00 EDT 2022
CMTM6 as a candidate risk gene for cervical cancer: Comprehensive bioinformatics study.
Frontiers in molecular biosciences
Huang X,Liu W,Liu C,Hu J,Wang B,Ren A,Huang X,Yuan Y,Liu J,Li M
Wed Jan 11 00:00:00 EST 2023
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Drug design, development and therapy
Li Y,Li C,Xiong Y,Fang B,Lin X,Huang Q
Wed Jun 15 00:00:00 EDT 2022
A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells.
Stem cell research & therapy
Wang L,Gao T,Li Y,Xie Y,Zeng S,Tai C,Feng Y,Shen P,Wang B
Fri Jun 17 00:00:00 EDT 2022
KCa3.1 inhibition-induced activation of the JNK/c-Jun signaling pathway enhances IL-10 expression in peripherally-induced regulatory T cells.
Journal of pharmacological sciences
Matsui M,Kajikuri J,Endo K,Kito H,Ohya S
Sat Jan 01 00:00:00 EST 2022
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Biochemical pharmacology
Zhao J,Chen S,Yang C,Zhou M,Yang T,Sun B,Zhu J,Zhang H,Lu Q,Li L,Yang Z,Song B,Shen W,Yi S,Dai S
Wed Jun 01 00:00:00 EDT 2022
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Shen Y,Teng L,Qu Y,Liu J,Zhu X,Chen S,Yang L,Huang Y,Song Q,Fu Q
Thu Feb 10 00:00:00 EST 2022
Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
Ma X,Zhang Y,Gou D,Ma J,Du J,Wang C,Li S,Cui H
Tue Jul 26 00:00:00 EDT 2022
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
International immunopharmacology
Liang R,Yuan Y,Bai Y,Liu X,Chen J,Jiang D,Meng D,Chen G,Li B,Zhou L,Guo W
Thu Sep 01 00:00:00 EDT 2022
Protective effects and possible mechanism of 6-gingerol against arsenic trioxide-induced nephrotoxicity based on network pharmacological analysis and experimental validation.
International immunopharmacology
Han X,Yang Y,Qi J,Zhang M,Xue Y,Chu X,Jia Q,Sun S,Guan S
Thu Sep 01 00:00:00 EDT 2022
Zinc Oxide Particles Can Cause Ovarian Toxicity by Oxidative Stress in Female Mice Model.
International journal of nanomedicine
Xu Y,Zhao Y,Liu S,Lv S,Chen L,Wang W,Feng Y,Fu F,Xu H
Tue Oct 25 00:00:00 EDT 2022
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Transplant immunology
Xu Z,Sun X,Ding B,Zi M,Ma Y
Sat Oct 01 00:00:00 EDT 2022
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Frontiers in endocrinology
Wang C,Sun Y
Tue Apr 19 00:00:00 EDT 2022
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
European journal of pharmacology
Shu J,Hu L,Wu Y,Chen L,Huang K,Wang Z,Liang M
Tue Mar 15 00:00:00 EDT 2022
GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis.
iScience
Cao C,Zhou Y,Zhang Y,Ma Y,Du S,Fan L,Niu R,Zhang Y,He M
Fri Jul 15 00:00:00 EDT 2022
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
International journal of molecular sciences
Xu Z,Hao X,Li M,Luo H
Sun Aug 28 00:00:00 EDT 2022
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
Food & function
Zhang X,Zhang B,Li L,Li X,Zhang J,Chen G
Mon Aug 01 00:00:00 EDT 2022
Downregulation of IL-8 and IL-10 by the Activation of Ca2+-Activated K+ Channel KCa3.1 in THP-1-Derived M2 Macrophages.
International journal of molecular sciences
Ohya S,Matsui M,Kajikuri J,Kito H,Endo K
Wed Aug 03 00:00:00 EDT 2022
Immune-enhancing effects of postbiotic produced by Bacillus velezensis Kh2-2 isolated from Korea Foods.
Food research international (Ottawa, Ont.)
Mi XJ,Tran THM,Park HR,Xu XY,Subramaniyam S,Choi HS,Kim J,Koh SC,Kim YJ
Tue Feb 01 00:00:00 EST 2022
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Antioxidants (Basel, Switzerland)
Zhan H,Pu Q,Long X,Lu W,Wang G,Meng F,Liao Z,Lan X,Chen M
Tue Nov 22 00:00:00 EST 2022
The Immune-Enhancing Properties of Hwanglyeonhaedok-Tang-Mediated Biosynthesized Gold Nanoparticles in Macrophages and Splenocytes.
International journal of nanomedicine
Mi XJ,Xu XY,Choi HS,Kim H,Cho IH,Yi TH,Kim YJ
Tue Feb 08 00:00:00 EST 2022
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Archives of biochemistry and biophysics
Ji R,Jia FY,Chen X,Wang ZH,Jin WY,Yang J
Sat Jan 15 00:00:00 EST 2022
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Aging
Jiang XL,Tai H,Kuang JS,Zhang JY,Cui SC,Lu YX,Qi SB,Zhang SY,Li SM,Chen JP,Meng XS
Thu Oct 27 00:00:00 EDT 2022
HIV-1 Tat Protein-Mediated Inflammatory Response Inhibits the Erythroid Hematopoietic Support Function of Bone Marrow Mesenchymal Stem Cells.
AIDS research and human retroviruses
Wang X,Chen M,Ma S,Ding Y,Zhou C,Yuan Y
Thu Sep 01 00:00:00 EDT 2022
System pharmacology analysis to decipher the effect and mechanism of active ingredients combination from herb couple on rheumatoid arthritis in rats.
Journal of ethnopharmacology
Wu SS,Xu XX,Shi YY,Chen Y,Li YQ,Jiang SQ,Wang T,Li P,Li F
Sun Apr 24 00:00:00 EDT 2022
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Journal of ethnopharmacology
Zhang XG,Liu AX,Zhang YX,Zhou MY,Li XY,Fu MH,Pan YP,Xu J,Zhang JQ
Thu Sep 15 00:00:00 EDT 2022
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Frontiers in cardiovascular medicine
Rui H,Zhao F,Yuhua L,Hong J
Tue Mar 21 00:00:00 EDT 2023
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.
Nature communications
Yan L,Zhang T,Wang K,Chen Z,Yang Y,Shan B,Sun Q,Zhang M,Zhang Y,Zhong Y,Liu N,Gu J,Xu D
Tue Nov 22 00:00:00 EST 2022
Heat shock protein 40 of Streptococcus pneumoniae induces immune response of human dendritic cells via TLR4-dependent p38 MAPK and JNK signaling pathways.
Immunity, inflammation and disease
Liu JJ,Lin JC,Chen LN
Thu Dec 01 00:00:00 EST 2022
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Journal of clinical laboratory analysis
Li Z,Xu Q,Huangfu N,Chen X,Zhu J
Sat Jan 01 00:00:00 EST 2022
TSH-TSHR axis promotes tumor immune evasion.
Journal for immunotherapy of cancer
Wu Z,Xi Z,Xiao Y,Zhao X,Li J,Feng N,Hu L,Zheng R,Zhang N,Wang S,Huang T
Sat Jan 01 00:00:00 EST 2022
Mechanism of HSP90 Inhibitor in the Treatment of DSS-induced Colitis in Mice by Inhibiting MAPK Pathway and Synergistic Effect of Compound Sophora Decoction.
Current pharmaceutical design
Yuan Y,Wu H,Shuai B,Liu C,Zhu F,Gao F,Wei C,Fan H
Fri Jan 06 00:00:00 EST 2023
Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders.
Journal of hazardous materials
Zhao T,Tang X,Li D,Zhao J,Zhou R,Shu F,Jia W,Fu W,Xia H,Liu G
Tue Feb 15 00:00:00 EST 2022
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Food & function
Bai X,Fu R,Duan Z,Liu Y,Zhu C,Fan D
Wed Apr 07 00:00:00 EDT 2021
RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway.
International journal of biological sciences
Zhang D,Jiang Q,Ge X,Shi Y,Ye T,Mi Y,Xie T,Li Q,Ye Q
Wed Mar 16 00:00:00 EDT 2022
G-Rh4 improves pancreatic β-cells dysfunction in vivo and in vitro by increased expression of Nrf2 and its target genes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liu Y,Deng J,Fan D
Mon Feb 01 00:00:00 EST 2021
[8]-Gingerol exerts anti-myocardial ischemic effects in rats via modulation of the MAPK signaling pathway and L-type Ca2+ channels.
Pharmacology research & perspectives
Xue Y,Zhang M,Zheng B,Zhang Y,Chu X,Liu Y,Li Z,Han X,Chu L
Fri Oct 01 00:00:00 EDT 2021
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Frontiers in pharmacology
Yong C,Zhang Z,Huang G,Yang Y,Zhu Y,Qian L,Tian F,Liu L,Wu Q,Xu Z,Chen C,Zhao J,Gao K,Zhou E
Wed Dec 15 00:00:00 EST 2021
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jia X,Zhu H,Li G,Lan M,Li X,Huang M,Xu W,Wu S
Sat May 01 00:00:00 EDT 2021
Lactobacillus plantarum MA2 Ameliorates Methionine and Choline-Deficient Diet Induced Non-Alcoholic Fatty Liver Disease in Rats by Improving the Intestinal Microecology and Mucosal Barrier.
Foods (Basel, Switzerland)
Wang Y,Zhang Y,Yang J,Li H,Wang J,Geng W
Thu Dec 16 00:00:00 EST 2021
Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis.
Cell death & disease
Liu S,Gu L,Wu N,Song J,Yan J,Yang S,Feng Y,Wang Z,Wang L,Zhang Y,Jin Y
Mon Oct 11 00:00:00 EDT 2021
Mitochondria transplantation protects traumatic brain injury via promoting neuronal survival and astrocytic BDNF.
Translational research : the journal of laboratory and clinical medicine
Zhao J,Qu D,Xi Z,Huan Y,Zhang K,Yu C,Yang D,Kang J,Lin W,Wu S,Wang Y
Wed Sep 01 00:00:00 EDT 2021
A human β-casein-derived peptide BCCY-1 modulates the innate immune response.
Food chemistry
Cai J,Li X,Wang X,Jiang C,Shen D,Cui X,Xie K,Ji C,Cao Y
Wed Jun 30 00:00:00 EDT 2021
Sympathetic activity is correlated with satellite cell aging and myogenesis via β2-adrenoceptor.
Stem cell research & therapy
Yuan S,Zheng S,Zheng K,Gao Y,Chen M,Li Y,Bai X
Thu Sep 16 00:00:00 EDT 2021
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Frontiers in pharmacology
Zhang X,Zhang Y,Zhou M,Xie Y,Dong X,Bai F,Zhang J
Fri Feb 04 00:00:00 EST 2022
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
Frontiers in oncology
Xu W,Zhou B,Wang J,Tang L,Hu Q,Wang J,Chen H,Zheng J,Yan F,Chen H
Fri Sep 10 00:00:00 EDT 2021
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
International immunopharmacology
Wang X,Chen S,Zhao L,Shi X
Sun Aug 01 00:00:00 EDT 2021
Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice.
Frontiers in nutrition
Huang F,Liu X,Xu S,Hu S,Wang S,Shi D,Wang K,Wang Z,Lin Q,Li S,Zhao S,Jin K,Wang C,Chen L,Wang F
Sun May 01 00:00:00 EDT 2022
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Molecules (Basel, Switzerland)
Zhang W,Zhu Y,Yu H,Liu X,Jiao B,Lu X
Sat Jan 09 00:00:00 EST 2021
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Journal of hazardous materials
Lai X,Wang M,Zhu Y,Feng X,Liang H,Wu J,Nie L,Li L,Shao L
Sat May 15 00:00:00 EDT 2021
PM2.5 exposure induces reproductive injury through IRE1/JNK/autophagy signaling in male rats.
Ecotoxicology and environmental safety
Yang Y,Feng Y,Huang H,Cui L,Li F
Mon Mar 15 00:00:00 EDT 2021
Nephrotoxicity and possible mechanisms of decabrominated diphenyl ethers (BDE-209) exposure to kidney in broilers.
Ecotoxicology and environmental safety
Sun S,Jin Y,Yang J,Zhao Z,Rao Q
Fri Jan 15 00:00:00 EST 2021
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Journal of ethnopharmacology
Zhou S,He Y,Zhang W,Xiong Y,Jiang L,Wang J,Cui X,Qu Y,Ge F
Tue Aug 10 00:00:00 EDT 2021
Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice.
Food & function
Cai G,Wu Y,Wusiman A,Gu P,Mao N,Xu S,Zhu T,Feng Z,Liu Z,Wang D
Mon Aug 02 00:00:00 EDT 2021
Bioactive constituents of Mosla chinensis-cv. Jiangxiangru ameliorate inflammation through MAPK signaling pathways and modify intestinal microbiota in DSS-induced colitis mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang X,Cheng K,Liu Z,Sun Y,Zhou L,Xu M,Dai X,Xiong Y,Zhang H
Wed Dec 01 00:00:00 EST 2021
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.
Antioxidants (Basel, Switzerland)
Wang L,Zhan J,Huang W
Sat Nov 28 00:00:00 EST 2020
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
International journal of biological macromolecules
Wu Z,Cheng Y,Yang Y,Gao Y,Sun X,Wang L,Sun Q,Zhang J,Xu X
Fri May 01 00:00:00 EDT 2020
Evi-1 Influence on Clinical Progress of Colorectal Cancer Patients.
Annals of clinical and laboratory science
Zhu Y,Zhang J,Ye Z,Peng P,Lan X,Xie L,Qin M,Huang J
Fri May 01 00:00:00 EDT 2020
Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway.
Aging
Fang H,Yang K,Tang P,Zhao N,Ma R,Luo X,Liu Q
Tue Jun 30 00:00:00 EDT 2020
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Theranostics
Lv W,Graves DT,He L,Shi Y,Deng X,Zhao Y,Dong X,Ren Y,Liu X,Xiao E,Zhang Y
Wed Apr 28 00:00:00 EDT 2021
Resveratrol-loaded biopolymer core-shell nanoparticles: bioavailability and anti-inflammatory effects.
Food & function
Liu Y,Liang X,Zou Y,Peng Y,McClements DJ,Hu K
Fri May 01 00:00:00 EDT 2020
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Herz
Yu T,Dong D,Guan J,Sun J,Guo M,Wang Q
Tue Dec 01 00:00:00 EST 2020
Antioxidants suppress radiation-induced apoptosis via inhibiting MAPK pathway in nasopharyngeal carcinoma cells.
Biochemical and biophysical research communications
Meng DF,Guo LL,Peng LX,Zheng LS,Xie P,Mei Y,Li CZ,Peng XS,Lang YH,Liu ZJ,Wang MD,Xie DH,Shu DT,Hu H,Lin ST,Li HF,Luo FF,Sun R,Huang BJ,Qian CN
Tue Jun 30 00:00:00 EDT 2020
IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease.
Aging
Wang M,Guo J,Zhao YQ,Wang JP
Fri Aug 28 00:00:00 EDT 2020
NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β-cells for protection.
Journal of cellular and molecular medicine
Pu ZQ,Liu D,Lobo Mouguegue HPP,Jin CW,Sadiq E,Qin DD,Yu TF,Zong C,Chen JC,Zhao RX,Lin JY,Cheng J,Yu X,Li X,Zhang YC,Liu YT,Guan QB,Wang XD
Tue Dec 01 00:00:00 EST 2020
Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma.
Oncology reports
An K,Zhang Y,Liu Y,Yan S,Hou Z,Cao M,Liu G,Dong C,Gao J,Liu G
Tue Sep 01 00:00:00 EDT 2020
Sigma-1 receptor protects against endoplasmic reticulum stress-mediated apoptosis in mice with cerebral ischemia/reperfusion injury.
Apoptosis : an international journal on programmed cell death
Zhao X,Zhu L,Liu D,Chi T,Ji X,Liu P,Yang X,Tian X,Zou L
Fri Feb 01 00:00:00 EST 2019
Sigma-1 receptor protects against endoplasmic reticulum stress-mediated apoptosis in mice with cerebral ischemia/reperfusion injury.
Apoptosis : an international journal on programmed cell death
Zhao X,Zhu L,Liu D,Chi T,Ji X,Liu P,Yang X,Tian X,Zou L
Fri Feb 01 00:00:00 EST 2019
Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Ren Z,Chen L,Wang Y,Wei X,Zeng S,Zheng Y,Gao C,Liu H
Fri Feb 01 00:00:00 EST 2019
Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Ren Z,Chen L,Wang Y,Wei X,Zeng S,Zheng Y,Gao C,Liu H
Fri Feb 01 00:00:00 EST 2019
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
Journal of cellular and molecular medicine
Tian L,Su CP,Wang Q,Wu FJ,Bai R,Zhang HM,Liu JY,Lu WJ,Wang W,Lan F,Guo SZ
Mon Jul 01 00:00:00 EDT 2019
Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension.
Neuroscience bulletin
Sun J,Ren XS,Kang Y,Dai HB,Ding L,Tong N,Zhu GQ,Zhou YB
Fri Feb 01 00:00:00 EST 2019
Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension.
Neuroscience bulletin
Sun J,Ren XS,Kang Y,Dai HB,Ding L,Tong N,Zhu GQ,Zhou YB
Fri Feb 01 00:00:00 EST 2019
Amyloid-β1-42 dynamically regulates the migration of neural stem/progenitor cells via MAPK-ERK pathway.
Chemico-biological interactions
Wang Z,Chen Y,Li X,Sultana P,Yin M,Wang Z
Fri Jan 25 00:00:00 EST 2019
Amyloid-β1-42 dynamically regulates the migration of neural stem/progenitor cells via MAPK-ERK pathway.
Chemico-biological interactions
Wang Z,Chen Y,Li X,Sultana P,Yin M,Wang Z
Fri Jan 25 00:00:00 EST 2019
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Aging
Liang S,Wang ZG,Zhang ZZ,Chen K,Lv ZT,Wang YT,Cheng P,Sun K,Yang Q,Chen AM
Fri Oct 11 00:00:00 EDT 2019
Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury.
The Journal of biological chemistry
Su L,Jiang X,Yang C,Zhang J,Chen B,Li Y,Yao S,Xie Q,Gomez H,Murugan R,Peng Z
Fri Dec 13 00:00:00 EST 2019
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Stem cell research & therapy
Shi A,Heinayati A,Bao D,Liu H,Ding X,Tong X,Wang L,Wang B,Qin H
Thu Jun 13 00:00:00 EDT 2019
MCP-induced protein 1 attenuates sepsis-induced acute lung injury by modulating macrophage polarization via the JNK/c-Myc pathway.
International immunopharmacology
Zhang Y,Huang T,Jiang L,Gao J,Yu D,Ge Y,Lin S
Tue Oct 01 00:00:00 EDT 2019
Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma.
Cell death & disease
Zhang C,Huang H,Zhang J,Wu Q,Chen X,Huang T,Li W,Liu Y,Zhang J
Mon Jun 17 00:00:00 EDT 2019
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Yonsei medical journal
Wang H,Peng X,Huang Y,Xiao Y,Wang Z,Zhan L
Sun Dec 01 00:00:00 EST 2019
Effect of CAPE-pNO2 against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
European journal of pharmacology
Li S,Huang Q,Zhang L,Qiao X,Zhang Y,Tang F,Li Z
Sat Jun 15 00:00:00 EDT 2019
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
Marine drugs
Lin F,Yang D,Huang Y,Zhao Y,Ye J,Xiao M
Fri Sep 20 00:00:00 EDT 2019
Caveolin-1 promotes Rfng expression via Erk-Jnk-p38 signaling pathway in mouse hepatocarcinoma cells.
Journal of physiology and biochemistry
Zhang C,Wu Q,Huang H,Chen X,Huang T,Li W,Liu Y,Zhang J
Fri Nov 01 00:00:00 EDT 2019
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Food & function
Ren D,Zhao Y,Zheng Q,Alim A,Yang X
Mon Apr 01 00:00:00 EDT 2019
Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells.
Biomolecules
Li M,Hao S,Li C,Xiao H,Sun L,Yu Z,Zhang N,Xiong Y,Zhao D,Yin Y
Thu Sep 19 00:00:00 EDT 2019
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Life sciences
Wu T,Jiang N,Ji Z,Shi G
Thu Aug 15 00:00:00 EDT 2019
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Life sciences
Wu T,Jiang N,Ji Z,Shi G
Thu Aug 15 00:00:00 EDT 2019
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Life sciences
Wu T,Jiang N,Ji Z,Shi G
Thu Aug 15 00:00:00 EDT 2019
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Mediators of inflammation
Wang W,Wu L,Li J,Ji J,Chen K,Yu Q,Li S,Feng J,Liu T,Zhang J,Chen J,Zhou Y,Mao Y,Wang F,Dai W,Fan X,Guo C,Wu J
Mon Feb 24 00:00:00 EST 2020
Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.
Thrombosis research
Wang Z,Ren J,Liu Q,Li J,Wu X,Wang W,Wu J,Wang G,Li J
Thu Nov 01 00:00:00 EDT 2018
Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.
Thrombosis research
Wang Z,Ren J,Liu Q,Li J,Wu X,Wang W,Wu J,Wang G,Li J
Thu Nov 01 00:00:00 EDT 2018
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
American journal of translational research
Chen T,Zhu H,Wang Y,Zhao P,Chen J,Sun J,Zhang X,Zhu G
Wed Sep 30 00:00:00 EDT 2020
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
American journal of translational research
Chen T,Zhu H,Wang Y,Zhao P,Chen J,Sun J,Zhang X,Zhu G
Wed Sep 30 00:00:00 EDT 2020
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
IL-1β promotes the migration of olfactory epithelium neural stem cells through activating matrix metalloproteinase expressions.
Pathology, research and practice
Pu Y,Liu H,Xu H,Liu H,Cheng Y,Chen X,Xu W,Xu Y,Fan J
Wed Aug 01 00:00:00 EDT 2018
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
International immunopharmacology
Peng Z,Gong X,Yang Y,Huang L,Zhang Q,Zhang P,Wan R,Zhang B
Wed Nov 01 00:00:00 EDT 2017
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
International journal of biological sciences
Sun L,Xu C,Chen G,Yu M,Yang S,Qiu Y,Peng K,Wang W,Xiao W,Yang H
Fri Apr 15 00:00:00 EDT 2016
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
International journal of biological sciences
Sun L,Xu C,Chen G,Yu M,Yang S,Qiu Y,Peng K,Wang W,Xiao W,Yang H
Fri Apr 15 00:00:00 EDT 2016
Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells.
PloS one
Wu T,Li Y,Huang D,Han F,Zhang YY,Zhang DW,Han J
Tue Jan 20 00:00:00 EST 2015
Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells.
PloS one
Wu T,Li Y,Huang D,Han F,Zhang YY,Zhang DW,Han J
Tue Jan 20 00:00:00 EST 2015
