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Product Details
BS-4312R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human KAT8, amino acids 301-400.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3), yeast YBF2 and SAS2, and TIP60 (HTATIP). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase MYST1; hMOF; K(lysine) acetyltransferase 8; Lysine acetyltransferase 8; Males-absent on the first protein homolog; mMof; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST protein 1; MYST-1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1; Protein acetyltransferase KAT8; Protein propionyltransferase KAT8
Gene Aliases: 2010203C02Rik; 5830450F21Rik; D7Ertd629e; hMOF; KAT8; MOF; MYST1; PP7073; ZC2HC8
UniProt ID: (Human) Q9H7Z6, (Mouse) Q9D1P2, (Rat) Q5XI06
Entrez Gene ID: (Human) 84148, (Mouse) 67773, (Rat) 310194
histone acetyltransferase activity
protein binding
transcription factor binding
acetyltransferase activity
enzyme binding
methylated histone binding
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
metal ion binding
histone acetyltransferase activity (H4-K16 specific)
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
molecular_function
histone modifying enzyme
transcription, DNA-templated
regulation of autophagy
histone acetylation
myeloid cell differentiation
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K16 acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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