QED Bioscience

KDEL Receptor Monoclonal Antibody (KR-10)

KDEL Receptor Antibody in Immunocytochemistry (ICC/IF)

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KDEL Receptor Antibody (11078-100UG) in ICC/IF

Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-KDEL Receptor Monoclonal Antibody, Clone KR-10 (11078). Tissue: NRK cells. Species: Rat. Primary Antibody: Mouse Anti-KDEL Receptor Monoclonal Antibody (11078) at 1:1000. Secondary Antibody: APC Goat Anti-Mouse (red). Counterstain: DAPI (blue) nuclear stain. KR-10 staining red; DAPI staining blue. Merged images. Courtesy of: Institute of Mol. ... View More

KDEL Receptor Antibody in Western Blot (WB)

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Product Details

11078-100UG

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

Immunocytochemistry (ICC/IF)

1:1,000

Product Specifications

Species Reactivity

Bovine, Dog, Chicken, Fruit fly, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

KR-10

Immunogen

Peptide corresponding to aa 192-212 of bovine KDEL receptor

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

2-8°C

Shipping conditions

Wet ice

Target Information

The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 108K heat shock protein; 108K HSP; 78 kDa glucose-regulated protein; 78-kD glucose-regulated protein precursor; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250|UniProtKB:P08113}; 98 kDa protein kinase; Binding-immunoglobulin protein; BiP; BiP protein; CG5183-PA; CG5183-PB; CG5183-PC; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Endoplasmic reticulum resident protein 99; Endoplasmin; endoplasmin {ECO:0000250|UniProtKB:P08113}; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; epididymis secretory sperm binding protein Li 89n; ER lumen protein retaining receptor 1; ER lumen protein retaining receptor 2; ER lumen protein-retaining receptor; ER lumen protein-retaining receptor 1; ERp99; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein GRP94; glucose-regulated protein, 78kDa; gp96 homolog; GRP 78; GRP-78; GRP-94; GRP94; Heat shock 108 kDa protein; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 108; heat shock protein 108.; heat shock protein 5; Heat shock protein 70 family protein 5; Heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250|UniProtKB:P08113}; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein 90kDa beta, member 1; Heat shock protein family A member 5; Heat shock protein family C member 4; heavy-chain binding protein BiP; HSP 108; hsp108; hsp70; HSP70 family protein 5; HSP90 beta; hsp90b1 {ECO:0000250|UniProtKB:P08113}; immunoglobulin binding protein; Immunoglobulin heavy chain-binding protein; KDEL; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; KDEL receptor-like protein; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; lethal (2) 31Em; Lys-Asp-Glu-Leu; Polymorphic tumor rejection antigen 1; PPK 98; Putative MAPK-activating protein PM23; RP23-446N16.1; Steroidogenesis-activator polypeptide; stress-inducible tumor rejection antigen gp96; Transferrin-binding protein; transforming growth factor alpha regulated gene 2; tumor rejection antigen (gp96) 1; Tumor rejection antigen 1; Tumor rejection antigen gp96; XAP-1 antigen

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Gene Aliases: 8030486F04Rik; AL022860; AU019543; AW215843; baffled; BEST:CK00230; BIP; BiP/Grp78; CG5183; CK00230; D2Wsu141e; D2Wsu17e; Dmel\CG5183; Dmel_CG5183; dmErd2; ECGP; endoplasmin; ERD2; ERD2.1; ERp99; GP96; GRP78; GRP94; HDEL; HEL-S-125m; HEL-S-89n; HEL35; Hsce70; hsp108; HSP90B1; HSPA5; hspa5a; HSPC4; I79_019946; I79_020931; KDELR; KDELR1; l(2)31Em; l(2)k00311; mBiP; MIF2; PM23; ppk98; SEZ-7; Sez7; TA-3; Targ2; Tra-1; TRA1; XAP-1; XELAEV_180384511mg