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Product Details
H00008462-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
8F4
Immunogen
KLF11 (NP_003588, 404 a.a. approximately 512 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: TYFKSSHLKA HLRTHTGEKP FNCSWDGCDK KFARSDELSR HRRTHTGEKK FVCPVCDRRF MRSDHLTKHA RRHMTTKKIP GWQAEVGKLN RIASAESPGS PLVSMPASA
Target Information
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Krueppel-like factor 11; Kruppel-like factor 11; TGFB-inducible early growth response protein 2; TIEG-2; Transforming growth factor-beta-inducible early growth response protein 2
Gene Aliases: FKLF; FKLF1; KLF11; MODY7; TIEG2; Tieg3
UniProt ID: (Human) O14901
Entrez Gene ID: (Human) 8462
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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