Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Basic krueppel-like factor; basic kruppel like factor; Basic Kruppel- like factor; basic Kruppel-like factor; CACCC-box-binding protein BKLF; Krueppel-like factor 3; Kruppel-like factor 3 (basic); MGC48279; TEF-2; transcript ch138
Gene Aliases: 9930027G08Rik; AL024007; BKLF; KLF3; Tef-2
UniProt ID: (Human) P57682, (Mouse) Q60980
Entrez Gene ID: (Human) 51274, (Mouse) 16599, (Rat) 114845
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