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KMO Antibody (PA5-100019) in IHC (P)
Immunohistochemistry analysis of KMO in human normal tissues adjacent to liver cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KMO polyclonal antibody (Product # PA5-100019) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-100019
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KMO(Accession O15229), corresponding to amino acid residues K333-E383.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2815549
Product Specific Information
Antibody detects endogenous levels of total KMO.
Target Information
Kynurenine 3-monooxygenase (KMO; EC 1.14.13.9) is an NADPH-dependent flavin monooxygenase that catalyzes the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KMO; kmo {ECO:0000312|RGD:620610}; Kynurenine 3-hydroxylase; kynurenine 3-hydroxylase {ECO:0000255|HAMAP-Rule:MF_03018}; Kynurenine 3-monooxygenase; kynurenine 3-monooxygenase {ECO:0000255|HAMAP-Rule:MF_03018}
Gene Aliases: AI046660; dJ317G22.1; KMO
UniProt ID: (Human) O15229, (Mouse) Q91WN4, (Rat) O88867
Entrez Gene ID: (Human) 8564, (Mouse) 98256, (Rat) 59113
tryptophan catabolic process
response to salt stress
tryptophan catabolic process to kynurenine
NAD metabolic process
quinolinate biosynthetic process
'de novo' NAD biosynthetic process from tryptophan
anthranilate metabolic process
secondary metabolite biosynthetic process
oxidation-reduction process
kynurenine metabolic process
metabolic process
pyridine nucleotide biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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