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Product Details
PA5-54433
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KCNA5. Recombinant protein control fragment (Product #RP-91088).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642910
Product Specific Information
Immunogen sequence: NFNYFYHRET DHEEPAVLKE EQGTQSQGPG LDRGVQRKVS GSRGSFCKAG GTLENADSAR RGSCPLEKCN VKAKSNVDLR RSLYALCLDT SRETDL
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
Target Information
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac potassium channel; HPCN1; insulinoma and islet potassium channel; MGC117058; MGC117059; potassium channel 1; potassium channel, voltage gated shaker related subfamily A, member 5; Potassium voltage-gated channel subfamily A member 5; potassium voltage-gated channel, shaker-related subfamily, member 5; Voltage-gated potassium channel HK2; voltage-gated potassium channel protein Kv1.5; Voltage-gated potassium channel subunit Kv1.5
Gene Aliases: ATFB7; HCK1; HK2; HPCN1; KCNA5; KV1.5; PCN1
UniProt ID: (Human) P22460
Entrez Gene ID: (Human) 3741
receptor binding
delayed rectifier potassium channel activity
protein binding
outward rectifier potassium channel activity
potassium channel inhibitor activity
protein kinase binding
alpha-actinin binding
voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
voltage-gated potassium channel activity involved in SA node cell action potential repolarization
scaffold protein binding
voltage-gated ion channel
response to hypoxia
potassium ion transport
Notch signaling pathway
response to mechanical stimulus
response to organic substance
regulation of vasoconstriction
regulation of membrane potential
response to hydrogen peroxide
regulation of potassium ion transport
negative regulation of potassium ion transport
regulation of insulin secretion
protein homooligomerization
negative regulation of cytosolic calcium ion concentration
potassium ion homeostasis
response to hyperoxia
membrane hyperpolarization
regulation of atrial cardiac muscle cell membrane repolarization
potassium ion export
potassium ion transmembrane transport
atrial cardiac muscle cell action potential
membrane repolarization during bundle of His cell action potential
membrane repolarization during SA node cell action potential
regulation of heart rate by cardiac conduction
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of myoblast proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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