Search Thermo Fisher Scientific
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Invitrogen
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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human KLK8/Kallikrein 8.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H NRPN; hK8; Kallikrein-8; kallikrein-related peptidase 8; Kallikrein8; Neuropsin; NP; Ovasin; PRO322; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein; UNQ283
Gene Aliases: HNP; KLK8; NP; NRPN; PRSS19; TADG14; UNQ283/PRO322
UniProt ID: (Human) O60259
Entrez Gene ID: (Human) 11202
Molecular Function:
protease
serine protease
protein modifying enzyme
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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