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FIGURE: 1 / 1
KiSS1 receptor Antibody (BS-2501R) in WB
Lane 1: Mouse Spinal cord lysates; Lane 2: Rat Spinal cord lysates probed with KiSS1 receptor Polyclonal Antibody, Unconjugated (bs-2501R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C.
Product Details
BS-2501R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human KiSS1 receptor, amino acids 121-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; hOT7T175; Hypogonadotropin-1; kiSS-; KiSS-1 receptor; KiSS-1R; Kisspeptins receptor; Metastin receptor; mOT7T175; orphan G protein-coupled receptor 54; orphan G protein-coupled receptor GPR54; rOT7T175
Gene Aliases: AXOR12; CPPB1; GPR54; HH8; HOT7T175; KiSS-1; KISS-1R; KISS1R
UniProt ID: (Human) Q969F8, (Mouse) Q91V45, (Rat) Q924U1
Entrez Gene ID: (Human) 84634, (Mouse) 114229, (Rat) 78976
activation of MAPKK activity
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
negative regulation of cell proliferation
calcium-mediated signaling
positive regulation of hormone secretion
arachidonic acid secretion
positive regulation of synaptic transmission
positive regulation of stress fiber assembly
signal transduction
chemical synaptic transmission
negative regulation of cell migration
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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